Date published: 2025-9-8

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GPT 抗体 (B-1): sc-271370

5.0(2)
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说明书
  • GPT抗体(B-1)是小鼠单克隆IgG3 (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于mouse物种的GPT的N-terminus的氨基酸2-33之间
  • 推荐用于 mouse 来源的GPT WB, IP, IF 和 ELISA检测
  • m-IgG3 BP-HRP是GPT Antibody (B-1) 适用于 WB 应用。 的首选辅助检测试剂,该试剂现与GPT Antibody (B-1) 搭配使用(请参阅下面的订购信息)。

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    関連項目

    谷氨酸丙酮酸转氨酶GPT(或GPT1)和GPT2,分别也称为丙氨酸氨基转移酶(ALT1和ALT2),催化丙氨酸和2-氧代戊二酸之间的可逆转氨作用,以形成丙酮酸和谷氨酸。随后,它们在葡萄糖和氨基酸的中间代谢中发挥关键作用。GPT和GPT2具有显著的序列同源性,但表达模式不同。GPT在肾、肝和心脏中高表达,而GPT2在肌肉、脂肪和肾脏中高表达。GPT在临床上被广泛用作肝脏完整性或肝细胞损伤的指标。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    GPT 抗体 (B-1) 参考文献:

    1. 在慢性肝病中谷丙转氨酶(GPT)抗体的演示。  |  Kajita, Y., et al. 1978. Clin Chim Acta. 89: 485-92. PMID: 101321
    2. 各种肝病中肝酶释放的机制。二、肝病患者血清和肝脏中谷草转氨酶(GOT)与谷丙转氨酶(GPT)的活性比率变化。  |  Miyake, S. 1979. Acta Med Okayama. 33: 343-58. PMID: 160182
    3. B6C3F1 gpt delta小鼠综合毒性研究中1-甲基萘的体内遗传毒性。  |  Jin, M., et al. 2012. J Toxicol Sci. 37: 711-21. PMID: 22863852
    4. 基因剂量证据表明谷丙转氨酶(谷氨酸-丙酮酸转氨酶;E.C. 2.6.1.2)基因座区域分配在8q24.2--8qter。  |  Rocha, J., et al. 1988. Hum Genet. 80: 299-300. PMID: 3192219
    5. 人红细胞谷氨酸-丙酮酸转氨酶(GPT EC 2.6.1.2)的琼脂糖凝胶电泳。  |  Bär, W. and Biedermann, V. 1987. Forensic Sci Int. 33: 69-73. PMID: 3817677
    6. 近期心肌梗塞后的谷草转氨酶(GOT)、谷丙转氨酶(GPT)和乳酸脱氢酶(LDH)水平以及血液黏度因子。ABO血型的影响。  |  Dintenfass, L. and Forbes, CD. 1974. Haematologia (Budap). 8: 523-33. PMID: 4461436
    7. 胆管运动障碍患者服用吗啡后血清谷丙转氨酶和血清乳酸脱氢酶升高。  |  Laursen, T. and Schmidt, A. 1966. Scand J Clin Lab Invest Suppl. 18: 175-7. PMID: 5958517
    8. 小鼠可溶性谷氨酸-丙酮酸转氨酶-1(Gpt-1)的染色体定位。  |  Eicher, EM. and Womack, JE. 1977. Biochem Genet. 15: 1-8. PMID: 849243
    9. 血清肌酐浓度、谷草转氨酶(S-GOT)和谷丙转氨酶(S-GPT)活性与铅暴露。  |  Tola, S. and Nordman, CH. 1977. Int Arch Occup Environ Health. 39: 37-44. PMID: 852897
    10. 开发了一种新型的CHL/IU细胞系,该细胞系含有gpt穿梭载体,可用于同时分析基因突变和染色体畸变。  |  Yamada, T., et al. 1997. Mutat Res. 393: 295-306. PMID: 9393622

    订购信息

    产品名称产品编号规格价格数量收藏夹

    GPT 抗体 (B-1)

    sc-271370
    200 µg/ml
    RMB2377.00

    GPT (B-1): m-IgG3 BP-HRP 套装

    sc-550405
    200 µg Ab; 40 µg BP
    RMB2662.00

    GPT (B-1) 中和勝肽

    sc-271370 P
    100 µg/0.5 ml
    RMB511.00

    Could we have a test sample for the following sample? GPT Antibody (B-1): sc-271370 it is s mouse anti-GPT1 but it seems you can use it in mouse liver tissue. how come? any background?

    Asked by: Dr Sebastien Serres
    Thank you for your question. Please contact Technical Service or your local distributor for information on how to receive a free 10 ug sample of this monoclonal antibody.
    Answered by: Tech Service
    Date published: 2020-02-20

    What application is the blocking peptide sc-271370 P appropriate for?

    Asked by: Randy McDonald
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Good Western Blot data of GPT expressionGood Western Blot data of GPT expression in mouse liver tissue extract. -SCBT QC
    Date published: 2015-04-16
    Rated 5 out of 5 by from Great Western Blot data of GPT expression in nonGreat Western Blot data of GPT expression in non-transfected and mouse GPT transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-10-30
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    GPT 抗体 (B-1) is rated 5.0 out of 5 by 2.
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