Date published: 2025-9-6

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GPR175 抗体 (6H2): sc-134350

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说明书
  • GPR175 抗体 6H2 是小鼠单克隆 IgG2b κ,GPR175抗体, 在1篇文献中引用,规格为100 µg/ml
  • 针对human重组GPR175蛋白的抗原性氨基酸
  • 推荐用于 mouse, rat 和 human 来源的GPR175 WB, IP 和 ELISA检测
  • 关于如何获取GPR175 (6H2): sc-134350免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成GPR175 抗体 (6H2)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

GPR175抗体(6H2)是一种IgG2b κ小鼠单克隆GPR175抗体,可通过WB、IP和ELISA检测小鼠、大鼠和人类的GPR175蛋白。GPR175抗体(6H2)可作为非共轭的抗GPR175抗体提供。G蛋白偶联受体(GPRs),也称为七次跨膜受体、七螺旋受体或7TM受体,是蛋白质超家族的一部分,在许多不同的刺激-反应途径中发挥作用。G蛋白偶联受体将细胞外信号转化为细胞内信号(G蛋白激活),并响应各种信号分子,如激素和神经递质。GPR175(G蛋白偶联受体175),也称为TPRA40或PP6566,是一种由373个氨基酸组成的多通道膜蛋白,普遍表达,并作为G蛋白偶联受体发挥作用。编码GPR175的基因位于人类3号染色体上,并以多种选择性剪接的同工型表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

GPR175 抗体 (6H2) 参考文献:

  1. 老年小鼠和糖尿病小鼠附睾脂肪中新型七跨膜结构域蛋白的差异表达  |  Yang, H., et al. 1999. Endocrinology. 140: 2859-67. PMID: 10342878
  2. TPRA40/GPR175通过Sjögren综合征相关蛋白NA14的功能膜转运调节小鼠早期胚胎发育。  |  Aki, T., et al. 2008. J Cell Physiol. 217: 194-206. PMID: 18459117
  3. 受体革命--G 蛋白偶联受体的多重性。  |  Larhammar, D., et al. 1993. Drug Des Discov. 9: 179-88. PMID: 8400001
  4. G 蛋白偶联受体。I. 受体与配体相互作用的多样性。  |  Ji, TH., et al. 1998. J Biol Chem. 273: 17299-302. PMID: 9651309

订购信息

产品名称产品编号规格价格数量收藏夹

GPR175 抗体 (6H2)

sc-134350
100 µg/ml
RMB2504.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with GPR175 (6H2): sc-134350 antibody?

Asked by: Dr Ninau Qelp
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Specific for GPR175 in Western BlotAntibody detects over-expressed human GPR175 in transfected lysate sc-116379 and mouse GPR175 in transfected lysate sc-120597. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from Works by western blot of transfected andWorks by western blot of transfected and endogenous Gpr175 (50kDa with glycosylation, 37kDa following PNGase F treatment), with a couple of background bands (data not published). Also works for IF (MeOH, PFA/TX-100) of transfected human and mouse Gpr175, as well as endogenous Gpr175 in primary cilia of C3H10T.5 cells. (Figure 3 of Singh et al 2015 J Biol Chem. 2015 Oct 8. pii: jbc.M115.665810). However, antibody is very sensitive to storage, as after a couple of months, it stops seeing endogenous ciliary staining, but still works on transfected (two lots)
Date published: 2015-10-26
Rated 3 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2013-05-23
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GPR175 抗体 (6H2) is rated 4.0 out of 5 by 3.
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