Date published: 2025-9-8

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GluR-5 抗体 (E-12): sc-393420

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说明书
  • GluR-5 抗体 E-12 是小鼠单克隆 IgG2a κ,GluR-5抗体, 在5篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列869-918位于human物种的GluR-5的C-terminus
  • GluR-5 抗体 (E-12) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 GluR-5
  • 抗GluR-5抗体(E-12)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取GluR-5 (E-12): sc-393420免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是GluR-5 Antibody (E-12) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与GluR-5 Antibody (E-12) 打包提供(请参阅下面的订购信息)。

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関連項目

GluR-5抗体(E-12)是一种IgG2a κ小鼠单克隆GluR-5抗体(也称为GRIK1抗体、谷氨酸离子型受体海人藻酸型亚单位1抗体、GLR5抗体、GLUR5抗体、GluK1抗体、gluR-5抗体、海人藻酸受体抗体、海人酸受体(KAR)抗体、谷氨酸受体海人藻酸家族抗体、离子型谷氨酸受体抗体、谷氨酸能离子通道受体抗体或兴奋性神经递质受体抗体),可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的GluR-5蛋白。GluR-5抗体(E-12)既有非偶联形式的抗GluR-5抗体,也有多种偶联形式的抗GluR-5抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。谷氨酸受体介导大脑中大多数兴奋性神经传递,并在神经可塑性、神经发育和神经退行性变中发挥重要作用。离子型谷氨酸受体分为NMDA受体和海人藻酸/AMPA受体,两者都含有谷氨酸门控的阳离子特异性离子通道。在许多突触中,海人藻酸/AMPA受体与NMDA受体共定位,并由七个结构相关的亚单位组成,指定为GluR-1至-7。海人藻酸/AMPA受体主要负责谷氨酸的快速兴奋性神经传递,而NMDA受体的功能特征是动力学缓慢和对Ca2+离子的高通透性。NMDA受体由五个亚单位组成:ε1、2、3、4和一个ζ亚单位。ζ亚单位在整个脑干中表达,而四个ε亚单位显示有限分布。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

GluR-5 抗体 (E-12) 参考文献:

  1. 水蛭中枢神经系统中谷氨酸受体5/6/7样和谷氨酸转运体1样免疫反应。  |  Thorogood, MS., et al. 1999. J Comp Neurol. 405: 334-44. PMID: 10076929
  2. 大鼠视觉皮层切片受到局灶性刺激时星状细胞上的单位 EPSC 的快速和慢速成分。  |  Stern, P., et al. 1992. J Physiol. 449: 247-78. PMID: 1326045
  3. 谷氨酸受体的分子多样性及其对大脑功能的影响。  |  Nakanishi, S. 1992. Science. 258: 597-603. PMID: 1329206
  4. 一种对多莫酸盐和钾离子具有高亲和力的谷氨酸受体通道。  |  Sommer, B., et al. 1992. EMBO J. 11: 1651-6. PMID: 1373382
  5. 生酮饮食对海马GluR5和Glu(6 mRNA表达以及钾离子诱导的癫痫模型中的Q/R位点编辑的影响。  |  Xu, X., et al. 2008. Epilepsy Behav. 13: 445-8. PMID: 18606572
  6. 谷氨酸神经毒性在缺氧缺血性神经元死亡中的作用  |  Choi, DW. and Rothman, SM. 1990. Annu Rev Neurosci. 13: 171-82. PMID: 1970230
  7. 脑干中五种 NMDA 受体通道亚基 mRNA 的不同分布。  |  Watanabe, M., et al. 1994. J Comp Neurol. 343: 520-31. PMID: 7518475
  8. 人类致痫新皮质中非NMDA离子型兴奋性氨基酸受体亚基GluR 2/3和GluR 5/6/7的免疫染色呈微区减少。  |  DeFelipe, J., et al. 1994. Brain Res. 657: 150-8. PMID: 7820613
  9. 发育中大鼠脑中的钾离子受体基因表达。  |  Bahn, S., et al. 1994. J Neurosci. 14: 5525-47. PMID: 8083752
  10. 克隆谷氨酸受体  |  Hollmann, M. and Heinemann, S. 1994. Annu Rev Neurosci. 17: 31-108. PMID: 8210177
  11. 记忆的突触模型:海马体的长期电位。  |  Bliss, TV. and Collingridge, GL. 1993. Nature. 361: 31-9. PMID: 8421494
  12. 大鼠 GluR7 和羧基末端剪接变体 GluR7b 是对谷氨酸敏感性较低的功能性 kainate 受体亚基。  |  Schiffer, HH., et al. 1997. Neuron. 19: 1141-6. PMID: 9390526

订购信息

产品名称产品编号规格价格数量收藏夹

GluR-5 抗体 (E-12)

sc-393420
200 µg/ml
RMB2377.00

GluR-5 (E-12): m-IgG Fc BP-HRP 套装

sc-530451
200 µg Ab; 10 µg BP
RMB2662.00

GluR-5 (E-12): m-IgGκ BP-HRP 套装

sc-523939
200 µg Ab, 40 µg BP
RMB2662.00

GluR-5 (E-12): m-IgG2a BP-HRP 套装

sc-547504
200 µg Ab; 10 µg BP
RMB2662.00

GluR-5 抗体 (E-12) AC

sc-393420 AC
500 µg/ml, 25% agarose
RMB3129.00

GluR-5 抗体 (E-12) HRP

sc-393420 HRP
200 µg/ml
RMB2377.00

GluR-5 抗体 (E-12) FITC

sc-393420 FITC
200 µg/ml
RMB2482.00

GluR-5 抗体 (E-12) PE

sc-393420 PE
200 µg/ml
RMB2580.00

GluR-5 抗体 (E-12) Alexa Fluor® 488

sc-393420 AF488
200 µg/ml
RMB2685.00

GluR-5 抗体 (E-12) Alexa Fluor® 546

sc-393420 AF546
200 µg/ml
RMB2685.00

GluR-5 抗体 (E-12) Alexa Fluor® 594

sc-393420 AF594
200 µg/ml
RMB2685.00

GluR-5 抗体 (E-12) Alexa Fluor® 647

sc-393420 AF647
200 µg/ml
RMB2685.00

GluR-5 抗体 (E-12) Alexa Fluor® 680

sc-393420 AF680
200 µg/ml
RMB2685.00

GluR-5 抗体 (E-12) Alexa Fluor® 790

sc-393420 AF790
200 µg/ml
RMB2685.00

I need to use an antibody to detect the protein in samples of avian origin. Do you know if sc-393420: GluR-5 (E-12) mouse monoclonal antibody will work?

Asked by: jenniferc
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 1 out of 5 by from IF not work.Test IF with this antibody on both embryonic and early postnatal mouse brain tissue. No signal could be detected.
Date published: 2019-03-15
Rated 5 out of 5 by from Good antibodyThis antibody is very big for me to help our laboratory has been using this antibody,we will always use .
Date published: 2017-05-25
Rated 5 out of 5 by from Recommended use.GluR-5 Antibody works very well. Knowledge of the sensitivity and specificity of GluR-5 Antibody leads to their more rational selection.
Date published: 2017-02-13
Rated 5 out of 5 by from recommend this productWe got nice bands for WB in rat brain tissue lysates,1:1000 been used,recommend use it.
Date published: 2017-02-02
Rated 5 out of 5 by from nice clear bandThe antibody orderd was used to detect GluR-5 protein levels. I used it detect human brain tissue extract, strong band seen for WB.
Date published: 2017-01-30
Rated 5 out of 5 by from Good Western blot data of GluRGood Western blot data of GluR-5 expression in mouse brain tissue extract. -SCBT QC
Date published: 2014-01-26
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GluR-5 抗体 (E-12) is rated 4.3 out of 5 by 6.
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