Date published: 2025-9-8
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
GluR-1 Antibody (E-6) - Western Blotting - Image 4630
GluR-1 抗体 (E-6): sc-13152. 小鼠脑组织提取物中 GluR-1 表达的 Western 印迹分析.
GluR-1 抗体 (E-6): sc-13152. 小鼠脑组织提取物中 GluR-1 表达的 Western 印迹分析.

GluR-1 抗体 (E-6): sc-13152

4.8(12)
寫評論提問

说明书
  • GluR-1抗体(E-6)是小鼠单克隆IgG1 κ, 在50篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于human物种的GluR-1的N-terminus附近的氨基酸33-51之间
  • 抗-GluR-1 抗体 (E-6) 推荐用于 WB, IP, IF 和 ELISA，检测mouse, rat 和human 来源的 GluR-1
  • 抗GluR-1抗体（E-6）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取GluR-1 (E-6): sc-13152的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP和 1 BP-HRP">m-IgG1 BP-HRP是GluR-1 Antibody (E-6) for WB applications. 的首选辅助检测试剂，这些试剂现与GluR-1 Antibody (E-6) 打包提供（请参阅下面的订购信息）。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

额外GluR抗体，包括GluR-1, GluR-2, GluR-4, GluR-5, GluR-δ 1和GluR-δ 2

GluR-1抗体（E-6）是一种小鼠单克隆IgG1 kappa轻链抗体，专门针对GluR-1蛋白，也称为GRIA1或谷氨酸受体AMPA型1。GluR-1 单克隆抗体（E-6）可识别人类 GluR-1 N 端附近 33-51 氨基酸内的表位，确保在多种物种（包括小鼠、大鼠和人类）中可靠检测。 GluR-1 是 AMPA 型离子型谷氨酸受体的重要组成部分，负责调节中枢神经系统中的大部分快速兴奋性神经传递。这些受体在突触可塑性、学习、记忆、神经发育中发挥着重要作用，还参与神经退行性变的基本机制。通过调节突触强度和可塑性，GluR-1对认知功能和有效的神经元通信至关重要。GluR-1 (E-6) 抗体用途广泛，适用于多种应用，如蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和酶联免疫吸附测定（ELISA）。抗GluR-1抗体（E-6）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物，能够满足各种实验需求。GluR-1 (E-6) 单克隆抗体有助于对 GluR-1 进行精确检测和深入研究，从而支持对突触功能和神经疾病的深入研究。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

GluR-1 抗体 (E-6) 参考文献:

  1. 大鼠视觉皮层切片受到局灶性刺激时星状细胞上的单位 EPSC 的快速和慢速成分。  |  Stern, P., et al. 1992. J Physiol. 449: 247-78. PMID: 1326045
  2. 谷氨酸受体的分子多样性及其对大脑功能的影响。  |  Nakanishi, S. 1992. Science. 258: 597-603. PMID: 1329206
  3. 谷氨酸神经毒性在缺氧缺血性神经元死亡中的作用  |  Choi, DW. and Rothman, SM. 1990. Annu Rev Neurosci. 13: 171-82. PMID: 1970230
  4. 偏头痛中GRIA1和GRIA3基因变异的病例对照研究。  |  Fang, J., et al. 2015. J Headache Pain. 17: 2. PMID: 26800698
  5. AMPA受体拮抗剂通过调节慢性癫痫大鼠的PP2B-ERK1/2-SGK1通路，促进NEDD4-2介导的GRIA1泛素化。  |  Kim, JE., et al. 2021. Biomedicines. 9: PMID: 34440273
  6. MicroRNA miR-18a-3p通过抑制谷氨酸AMPA受体亚基1基因（GRIA1）促进骨质疏松并可能导致脊柱骨折。  |  Zhao, M., et al. 2022. Bioengineered. 13: 370-382. PMID: 34937502
  7. ID患者中GRIA1错义和截短变异的鉴定和功能评估：一种新兴的神经发育综合征。  |  Ismail, V., et al. 2022. Am J Hum Genet. 109: 1217-1241. PMID: 35675825
  8. 恢复胰腺α细胞中的谷氨酸受体信号可恢复1型糖尿病的胰高血糖素反应。  |  Panzer, JK., et al. 2022. Cell Rep. 41: 111792. PMID: 36516761
  9. 脑干中五种 NMDA 受体通道亚基 mRNA 的不同分布。  |  Watanabe, M., et al. 1994. J Comp Neurol. 343: 520-31. PMID: 7518475
  10. 克隆谷氨酸受体  |  Hollmann, M. and Heinemann, S. 1994. Annu Rev Neurosci. 17: 31-108. PMID: 8210177
  11. 记忆的突触模型：海马体的长期电位。  |  Bliss, TV. and Collingridge, GL. 1993. Nature. 361: 31-9. PMID: 8421494
  12. 大鼠 GluR7 和羧基末端剪接变体 GluR7b 是对谷氨酸敏感性较低的功能性 kainate 受体亚基。  |  Schiffer, HH., et al. 1997. Neuron. 19: 1141-6. PMID: 9390526

订购信息

产品名称产品编号规格价格数量收藏夹

GluR-1 抗体 (E-6)

sc-13152
200 µg/ml
RMB2377.00

GluR-1 (E-6): m-IgG Fc BP-HRP 套装

sc-526544
200 µg Ab; 10 µg BP
RMB2662.00

GluR-1 (E-6): m-IgG1 BP-HRP 套装

sc-531917
200 µg Ab; 20 µg BP
RMB2662.00

GluR-1 抗体 (E-6) AC

sc-13152 AC
500 µg/ml, 25% agarose
RMB3129.00

GluR-1 抗体 (E-6) HRP

sc-13152 HRP
200 µg/ml
RMB2377.00

GluR-1 抗体 (E-6) FITC

sc-13152 FITC
200 µg/ml
RMB2482.00

GluR-1 抗体 (E-6) PE

sc-13152 PE
200 µg/ml
RMB2580.00

GluR-1 抗体 (E-6) Alexa Fluor® 488

sc-13152 AF488
200 µg/ml
RMB2685.00

GluR-1 抗体 (E-6) Alexa Fluor® 546

sc-13152 AF546
200 µg/ml
RMB2685.00

GluR-1 抗体 (E-6) Alexa Fluor® 594

sc-13152 AF594
200 µg/ml
RMB2685.00

GluR-1 抗体 (E-6) Alexa Fluor® 647

sc-13152 AF647
200 µg/ml
RMB2685.00

GluR-1 抗体 (E-6) Alexa Fluor® 680

sc-13152 AF680
200 µg/ml
RMB2685.00

GluR-1 抗体 (E-6) Alexa Fluor® 790

sc-13152 AF790
200 µg/ml
RMB2685.00

GluR-1 (E-6) 中和勝肽

sc-13152 P
100 µg/0.5 ml
RMB511.00

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: DefinitelyNotMatt
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety Please contact Technical Service if you have further questions concerning this product.
Answered by: Technical Support 2
Date published: 2017-01-12

I am using GluR-1 Antibody (E-6): sc-13152 for Western blot. How do I know if the band I am detecting is specific?

Asked by: DefinitelyNotMatt
Thank you for your question. We recommend using the blocking peptide sc-13152 P as a negative control. Antibody binding to antigen may be blocked/competed by pre-absorption with the blocking peptide. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization Please contact Technical Service if you have further questions concerning this product.
Answered by: Technical Support 2
Date published: 2017-01-12
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_13152, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 100ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from This is very specificUse GluR-1 for variety of cell lines and it always works well
Date published: 2018-02-21
Rated 5 out of 5 by from good performanceWe test this GluR-1 use this antibody (rat brain tissue extracts 60ug.),1:500 dilution been used.I recommend did ponceau staining after transfer to confirmed whether the target band is on the membrance.Very good performance.
Date published: 2017-09-16
Rated 5 out of 5 by from in WB in humanWe use it detect the GluR-1 in human cerebellum tissue, the dilution(1:500) is enough to western blot
Date published: 2017-05-16
Rated 5 out of 5 by from in WB worked wellIt gives an excellent western blotting signal both in human brain tissue
Date published: 2017-04-28
Rated 5 out of 5 by from Strog WBGreat product for western blot applications; strong, clear signal
Date published: 2017-01-30
Rated 5 out of 5 by from Good GluR-1 signalGood, well-published antibody for GluR-1 detection in mouse, rat, and human samples. Strong signal in all three species observed in Western blot.
Date published: 2017-01-24
Rated 5 out of 5 by from hao我博士期间的课题一直在用这个抗体，western, Co-IP推荐！希望santa cruz能搞活动让大家试用一下！
Date published: 2016-11-15
Rated 4 out of 5 by from Good antibody for IF in mouse neuronal cellsGood antibody for IF in mouse neuronal cells.
Date published: 2015-12-07
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_12
  • loc_zh_CN, sid_13152, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT
GluR-1 抗体 (E-6) is rated 4.8 out of 5 by 12.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_12
  • loc_zh_CN, sid_13152, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 124ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。