Date published: 2026-10-20

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Gl Syn 抗体 (D-6): sc-376767

4.6(5)
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说明书
  • Gl Syn抗体(D-6)是小鼠单克隆IgG3 κ, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的GI Syn的N-terminus附近的氨基酸61-101之间
  • 推荐用于 mouse, rat 和 human 来源的GI Syn WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • m-IgGκ BP-HRP是Gl Syn Antibody (D-6) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。该试剂现可与Gl Syn Antibody (D-6) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGκ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。
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関連項目

谷氨酰胺合成酶(GI Syn)形成八聚体,作为谷氨酸胺化形成谷氨酰胺的催化剂。该酶是星形胶质细胞的标志物,星形胶质细胞是大脑中谷氨酸转化为谷氨酰胺的主要场所。星形胶质细胞与神经元接触后,谷氨酰胺合成酶被诱导。已证明,胶质细胞中谷氨酰胺合成酶表达升高可保护神经元免受过量谷氨酸引起的变性。谷氨酰胺合成酶也存在于肝脏中,参与氮平衡。原发性肝癌中谷氨酰胺合成酶过表达,表明谷氨酰胺合成酶在肝细胞转化中可能起作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Gl Syn 抗体 (D-6) 参考文献:

  1. 谷氨酰胺合成酶抑制剂及其在医学中的潜在应用。  |  Berlicki, Ł. 2008. Mini Rev Med Chem. 8: 869-78. PMID: 18691144
  2. 糖皮质激素介导的骨骼肌谷氨酰胺合成酶诱导作用  |  Max, SR. 1990. Med Sci Sports Exerc. 22: 325-30. PMID: 1974319
  3. GLUL基因变异可预测2型糖尿病患者的全因死亡率  |  Prudente, S., et al. 2015. Diabetes. 64: 2658-63. PMID: 25677913
  4. 全基因组关联分析确定了家族性乙型肝炎病毒相关肝细胞癌的 GLUL 单倍型。  |  Lin, YY., et al. 2017. Cancer. 123: 3966-3976. PMID: 28662289
  5. 谷氨酰胺合成酶在氨稳态中的新作用  |  Zhou, Y., et al. 2020. Neurochem Int. 140: 104809. PMID: 32758585
  6. 谷氨酰胺合成酶基因缺失会破坏唐氏利什曼原虫的存活性和感染性  |  Kumar, V., et al. 2021. Front Cell Infect Microbiol. 11: 622266. PMID: 33732662
  7. 通过 His-Tag Pull-Down 鉴定谷氨酰胺合成酶是一种康地班-Bt 结合蛋白  |  Han, P., et al. 2022. Protein Pept Lett. 29: 71-79. PMID: 34961439
  8. TERT沉默改变了T98G细胞系中ARG1、GLUL、VIM、NES基因和hsa-miR-29b-3p的表达。  |  González-Giraldo, Y., et al. 2023. Nucleosides Nucleotides Nucleic Acids. 42: 464-477. PMID: 36533634
  9. 谷氨酰胺合成酶有助于调控黄曲霉的生长、分生孢子、硬菌丝发育和抵抗氧化应激。  |  Wang, S., et al. 2022. Toxins (Basel). 14: PMID: 36548719
  10. 谷氨酰胺合成酶基因的进化符合分子进化的中性理论。  |  Tateno, Y. 1994. Jpn J Genet. 69: 489-502. PMID: 7999370

订购信息

产品名称产品编号规格价格数量收藏夹

Gl Syn 抗体 (D-6)

sc-376767
200 µg/ml
CNY2422.00

Gl Syn (D-6): m-IgGκ BP-HRP 套装

sc-552437
200 µg Ab; 40 µg BP
CNY2715.00

Gl Syn (D-6) 中和勝肽

sc-376767 P
100 µg/0.5 ml
CNY519.00

What application is the blocking peptide sc-376767 P appropriate for?

Asked by: Randy McDonald
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_10, d_19, h_5CST
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Rated 5 out of 5 by zhaofei from specific bandShowing only one specific band on western blot for HepG2 cell. Dilution is 1:1000.
Date published: 2017-05-09
Rated 5 out of 5 by Germaine from Recommended for IFGreat cytoplasmic immunofluorescence staining of methanol-fixed HeLa cells
Date published: 2017-02-01
Rated 4 out of 5 by ET from Nice bands detected in WB using human liverNice bands detected in WB using human liver and mouse brain tissue extracts. -SCBT QC
Date published: 2015-04-15
Rated 4 out of 5 by JL from Strong band seen in WB using KNRK whole cellStrong band seen in WB using KNRK whole cell lysate. -SCBT QC
Date published: 2015-03-23
Rated 5 out of 5 by MC from Produced excellent immunoperoxidase cytoplamsicProduced excellent immunoperoxidase cytoplamsic staining in formalin fixed, paraffin-embedded human liver tissue. -SCBT QC
Date published: 2015-03-10
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Gl Syn 抗体 (D-6) is rated 4.6 out of 5 by 5.
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