Date published: 2025-9-7

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Gβ 5 抗体 (F-5): sc-365758

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说明书
  • Gβ 5 抗体(F-5)是小鼠单克隆IgG2a κ, 在1篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Gβ 5的N-terminus附近的氨基酸21-47之间
  • 推荐用于 mouse, rat, human 和 来源的Gβ 5 long and short forms WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 canine, bovine, porcine and avian
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是Gβ 5 Antibody (F-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Gβ 5 Antibody (F-5) 打包提供(请参阅下面的订购信息)。

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関連項目

异源三聚体G蛋白的功能是将信息从细胞膜受体传递到细胞内效应器。范围非常广泛的受体中的每一个都特异性地检测细胞外刺激(即光子、信息素、气味剂、激素或神经递质),而生成一个或多个细胞内信使的效应器(例如,腺苷酸环化酶)则数量较少。G蛋白复合物的每个亚基都由三个相应基因家族(α、β、γ)中的一个成员编码。在哺乳动物中,β亚基家族有五个不同的成员。G蛋白的β亚基是G蛋白α亚基以及某些信号转导受体和效应器的重要调节因子。与至少具有83%同源性的G β1-4相比,G β5仅与其他β亚基有50%的同源性。人类G β5在脑、胰腺、肾脏和心脏中高表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Gβ 5 抗体 (F-5) 参考文献:

  1. 照亮 Gbeta5 信号。  |  Zeller, CE. and Dohlman, HG. 2007. Mol Pharmacol. 72: 810-1. PMID: 17636044
  2. Gβ5-RGS 复合物的结构、功能和定位。  |  Slepak, VZ. 2009. Prog Mol Biol Transl Sci. 86: 157-203. PMID: 20374716
  3. Gβ5 在视觉中的作用  |  Morhardt, DR., et al. 2009. Prog Mol Biol Transl Sci. 86: 229-48. PMID: 20374718
  4. 主要神经元 G 蛋白调节因子 RGS7-Gβ5-R7BP 复合物的结构组织。  |  Patil, DN., et al. 2018. Elife. 7: PMID: 30540250
  5. 鉴定 RGS7/Gβ5/R7BP 复合物的潜在调节剂  |  Stoveken, HM., et al. 2021. SLAS Discov. 26: 1177-1188. PMID: 34112017
  6. 与 RGS7-Gβ5 信号复合体耦合的人类 GPR158 受体的冷冻电镜结构。  |  Patil, DN., et al. 2022. Science. 375: 86-91. PMID: 34793198
  7. C 类孤儿 GPCR GPR158 与 RGS7-Gβ5 复合物的结构。  |  Jeong, E., et al. 2021. Nat Commun. 12: 6805. PMID: 34815401
  8. Gβ5 对机械痛觉的特异性调节涉及 GABA-B 受体。  |  Pandey, M., et al. 2023. JCI Insight. 8: PMID: 37219953
  9. 通过 Gβ5 和 GRK3 对μ-阿片受体上的β-阿司匹林招募进行信号剖面和空间调控。  |  Carino, CMC., et al. 2025. Eur J Pharmacol. 987: 177151. PMID: 39579957
  10. 视网膜中 Gbeta5-RGS7 蛋白复合物的鉴定。  |  Cabrera, JL., et al. 1998. Biochem Biophys Res Commun. 249: 898-902. PMID: 9731233

订购信息

产品名称产品编号规格价格数量收藏夹

Gβ 5 抗体 (F-5)

sc-365758
200 µg/ml
RMB2377.00

Gβ 5 (F-5): m-IgG Fc BP-HRP 套装

sc-537833
200 µg Ab; 10 µg BP
RMB2662.00

Gβ 5 (F-5): m-IgGκ BP-HRP 套装

sc-535254
200 µg Ab; 40 µg BP
RMB2662.00

Gβ 5 (F-5): m-IgG2a BP-HRP 套装

sc-548128
200 µg Ab; 10 µg BP
RMB2662.00

Gβ 5 (F-5) 中和勝肽

sc-365758 P
100 µg/0.5 ml
RMB511.00

Hi, Do you provide free sample to test before purchase?

Asked by: Ahmed1980
Thank you for your question. We do not currently offer a free 10 ug sample size for this specific antibody. However, we do offer a free 10 ug sample size for an alternative antibody to the same target, Gβ 5 Antibody (C-6): sc-515379. Please contact our Technical Service Department for more information on how to receive a free 10 ug sample of the monoclonal antibody.
Answered by: Technical Support
Date published: 2019-03-14

What application is the blocking peptide sc-365758 P appropriate for?

Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from StrongStrong, robust band observed via Western Blot using mouse brain tissue extract. -SCBT QC
Date published: 2013-06-06
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G β 5 抗体 (F-5) is rated 5.0 out of 5 by 1.
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