Date published: 2025-9-8

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Fra1 抗体 (B-10): sc-48424

5.0(2)
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说明书
  • Fra1 抗体 B-10 是小鼠单克隆 IgG1, 在2篇文献中引用,提供 200 µg/ml
  • 推荐用于 mouse, rat 和 human 来源的Fra-1 WB, IP, IF 和 ELISA检测
  • 看 Fra1 (D-3): sc-376148,可查看有标记的 Fra1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Fra1 抗体 (B-10)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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v-Fos癌基因最初是在两个独立的小鼠骨肉瘤病毒分离株和一个禽类肾母细胞瘤病毒中检测到的。c-Fos基因家族的成员,包括c-Fos、Fos B、Fra-1和Fra-2,编码核磷蛋白,这些蛋白能被各种因子快速且短暂地诱导,并作为几个基因的转录调节因子。与形成同源和异源二聚体并与特定DNA反应元件结合的c-Jun蛋白不同,c-Fos蛋白仅与Jun基因家族的成员形成异源二聚体时才具有活性。此外,选定的ATF/CREB家族成员可以与Fos和Jun形成亮氨酸拉链二聚体。不同的二聚体对AP-1和CRE位点表现出不同的特异性和亲和力。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Fra1 抗体 (B-10)

sc-48424
200 µg/ml
RMB2377.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with Fra-1 (B-10): sc-48424 monoclonal antibody?

Asked by: Professor Griffin
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from An increase in signal observed by WB whenAn increase in signal observed by WB when comparing untreated 3611-RF and PMA induced 3611-RF nuclear extracts. -SCBT QC
Date published: 2015-06-22
Rated 5 out of 5 by from Good specificity shown by using transfectedGood specificity shown by using transfected and non-transfected 293T cells for over-expression of the human Fra-1 protein via Western Blot analysis. -SCBT QC
Date published: 2013-08-29
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Fra1 抗体 (B-10) is rated 5.0 out of 5 by 2.
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