Date published: 2025-9-7

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FMNL1 抗体 (A-4): sc-390466

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说明书
  • FMNL1 抗体 A-4 是小鼠单克隆 IgG1 κ,FMNL1抗体, 在4篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列161-220位于human物种的FMNL1的内部区域内
  • FMNL1 抗体 (A-4) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 FMNL1
  • 抗FMNL1抗体(A-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取FMNL1 (A-4): sc-390466免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是FMNL1 Antibody (A-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与FMNL1 Antibody (A-4) 打包提供(请参阅下面的订购信息)。

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関連項目

FMNL1抗体(A-4)是一种IgG1 κ小鼠单克隆FMNL1抗体(也称为FMNL1抗体),可通过WB、IP、IF和ELISA等方法检测小鼠、大鼠和人源的FMNL1蛋白。FMNL1抗体(A-4)既可作为非偶联的抗FMNL1抗体形式提供,也可作为多种抗FMNL1抗体的偶联形式提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。Formin样蛋白1(FMNL1,formin相关蛋白,Frl)是一种由小鼠基因Fmnl1编码的含有1094个氨基酸的蛋白质。FMNL1属于formin同源家族,含有一个DAD(透明自调节域)、一个FH2(formin同源2)域和一个GBD/FH3(Rho GTPase结合/formin同源3)域。Formins是在所有真核生物中表达的一类保守蛋白质,已知在生成细胞肌动蛋白基结构方面发挥作用。FMNL1被认为在控制细胞运动和巨噬细胞存活方面发挥作用。已发现FMNL1与Rac 1、PFN1和PFN2相互作用,可以阻断细胞凋亡并抑制细胞粘附和迁移。FMNL1位于细胞质中,在脾脏、淋巴结和骨髓细胞中高度表达。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

FMNL1 抗体 (A-4) 参考文献:

  1. FRL是一种新型甲形蛋白相关蛋白,它与Rac结合并调节巨噬细胞的细胞运动和存活。  |  Yayoshi-Yamamoto, S., et al. 2000. Mol Cell Biol. 20: 6872-81. PMID: 10958683
  2. 人类 FMNL1, FMNL2 和 FMNL3 基因的鉴定和特征描述。  |  Katoh, M. and Katoh, M. 2003. Int J Oncol. 22: 1161-8. PMID: 12684686
  3. 小鼠甲形蛋白 FRLalpha 能减缓肌动蛋白丝倒钩末端的伸长,与盖层蛋白竞争,加速单体聚合,并切断肌动蛋白丝。  |  Harris, ES., et al. 2004. J Biol Chem. 279: 20076-87. PMID: 14990563
  4. 人类 FMN1 基因的硅学鉴定和特征描述。  |  Katoh, M. and Katoh, M. 2004. Int J Mol Med. 14: 121-6. PMID: 15202026
  5. T 型非霍奇金淋巴瘤中 FMNL1 蛋白的高表达。  |  Favaro, PM., et al. 2006. Leuk Res. 30: 735-8. PMID: 16494944
  6. Formins调节中心体向免疫突触的肌动蛋白相关蛋白2/3复合物独立极化。  |  Gomez, TS., et al. 2007. Immunity. 26: 177-90. PMID: 17306570
  7. 请走这边。  |  Schwartzberg, PL. 2007. Immunity. 26: 139-41. PMID: 17307700

订购信息

产品名称产品编号规格价格数量收藏夹

FMNL1 抗体 (A-4)

sc-390466
200 µg/ml
RMB2377.00

FMNL1 (A-4): m-IgGκ BP-HRP 套装

sc-523542
200 µg Ab, 40 µg BP
RMB2662.00

FMNL1 (A-4): m-IgG1 BP-HRP 套装

sc-533591
200 µg Ab; 20 µg BP
RMB2662.00

FMNL1 抗体 (A-4) AC

sc-390466 AC
500 µg/ml, 25% agarose
RMB3129.00

FMNL1 抗体 (A-4) HRP

sc-390466 HRP
200 µg/ml
RMB2377.00

FMNL1 抗体 (A-4) FITC

sc-390466 FITC
200 µg/ml
RMB2482.00

FMNL1 抗体 (A-4) PE

sc-390466 PE
200 µg/ml
RMB2580.00

FMNL1 抗体 (A-4) Alexa Fluor® 488

sc-390466 AF488
200 µg/ml
RMB2685.00

FMNL1 抗体 (A-4) Alexa Fluor® 546

sc-390466 AF546
200 µg/ml
RMB2685.00

FMNL1 抗体 (A-4) Alexa Fluor® 594

sc-390466 AF594
200 µg/ml
RMB2685.00

FMNL1 抗体 (A-4) Alexa Fluor® 647

sc-390466 AF647
200 µg/ml
RMB2685.00

FMNL1 抗体 (A-4) Alexa Fluor® 680

sc-390466 AF680
200 µg/ml
RMB2685.00

FMNL1 抗体 (A-4) Alexa Fluor® 790

sc-390466 AF790
200 µg/ml
RMB2685.00

Morning , I would like to obtain a free, small trial sample of this antibody as suggested in spanish ( Contacte con nosotros para recibir GRATIS 10 µg de muestra de FMNL1 (A-4): sc-390466.). Best

Asked by: MANUEL IZQUIERDO
For a limited time, we are offering a free 10 µg sample of this antibody. Please select your state and see the distributors or branch office you can request from, https://www.scbt.com/scbt/resources/distributors For more questions, please contact us by live chat on our website.
Answered by: Technical Support 15
Date published: 2017-12-15

What is the recommended starting dilution for Western blot for sc-390466: FMNL1 (A-4) monoclonal antibody?

Asked by: jenniferc
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 1 out of 5 by from Not good, lot number stains WT and KO cellsWe bought the latest lot and we got non specific binding that showed up in our FMNL1 KO cells. Signal was punctate and non-specific, unfortunately
Date published: 2024-10-15
Rated 5 out of 5 by from Specific stainingWe tested this antibody for immunofluorescence staining and obtained good specific staining compared to FMNL1-deficient cells.
Date published: 2018-03-03
Rated 5 out of 5 by from Produced positive Western blot data of FMNL1Produced positive Western blot data of FMNL1 expression in HuT 78 and Jurkat whole cell lysates. -SCBT QC
Date published: 2014-06-27
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FMNL1 抗体 (A-4) is rated 3.7 out of 5 by 3.
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