Date published: 2026-10-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

Fibronectin 抗体 (IST-1): sc-59824

4.7(3)
寫評論提問
说明书
  • Fibronectin抗体(IST-1)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 针对从human来源的血浆中分离的纯化纤维蛋白原
  • 推荐用于 mouse, rat 和 human 来源的cellular and plasma Fibronectin WB, IP, IF, IHC(P) 和 FCM检测
  • 看 Fibronectin (EP5): sc-8422,可查看有标记的 Fibronectin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是Fibronectin Antibody (IST-1) for WB and IHC(P) applications. 的首选辅助检测试剂,这些试剂现与Fibronectin Antibody (IST-1) 打包提供(请参阅下面的订购信息)。
Gene Editing Promo Banner

快捷链接

関連項目

纤维连接蛋白是一种细胞外基质糖蛋白,存在于大多数细胞表面、细胞外液和血浆中。它是一种高分子量的异二聚体蛋白,最初被发现是病毒转化细胞表面缺失的蛋白质,已被证明参与各种功能,包括细胞粘附、细胞运动和伤口愈合。选择性剪接和糖基化产生了几种不同形式的纤维连接蛋白,其中一些表现出有限的组织分布或与恶性肿瘤有关。已经证明,肌成纤维细胞表型的形成与迪皮特伦病中糖基化纤维连接蛋白和纤维连接蛋白剪接变异体的发生有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Fibronectin 抗体 (IST-1) 参考文献:

  1. 纤维粘连蛋白的紧密构象由分子内离子相互作用决定。  |  Johnson, KJ., et al. 1999. J Biol Chem. 274: 15473-9. PMID: 10336438
  2. 新型突变的人纤维粘连蛋白 FIII9-10 结构域对具有更高的构象稳定性和生物活性。  |  van der Walle, CF., et al. 2002. Protein Eng. 15: 1021-4. PMID: 12601142
  3. 纤维粘连蛋白介导成骨细胞附着于体外基质的机制。  |  Puleo, DA. and Bizios, R. 1992. Bone Miner. 18: 215-26. PMID: 1392695
  4. 糖尿病视网膜病变中的肿瘤胎儿纤连蛋白。  |  Khan, ZA., et al. 2004. Invest Ophthalmol Vis Sci. 45: 287-95. PMID: 14691186
  5. 纤连蛋白的中心细胞结合域支持病灶粘附形成和 Rho 信号转导。  |  Wang, R., et al. 2005. J Biol Chem. 280: 28803-10. PMID: 15964831
  6. 纤连蛋白在禽类心前细胞迁移中的作用。II. 心脏形成区在不同阶段的旋转及其影响。  |  Linask, KK. and Lash, JW. 1988. Dev Biol. 129: 324-9. PMID: 3417041
  7. 化学修饰后纤维粘连蛋白生物活性的稳定性。  |  Gold, LI. and Pearlstein, E. 1979. Biochim Biophys Acta. 581: 237-51. PMID: 518912
  8. 急性白血病中的纤维粘连蛋白C。  |  Reilly, JT., et al. 1984. Br J Haematol. 58: 83-90. PMID: 6466574
  9. 血浆纤维粘连蛋白抗原和抗血清的制备  |  Scott, DL., et al. 1981. J Immunol Methods. 43: 29-33. PMID: 7264318
  10. 纤连蛋白的细胞粘附和基质组装结构域激活了不同的 alpha5beta1 介导的信号通路。  |  Hocking, DC., et al. 1998. J Cell Biol. 141: 241-53. PMID: 9531562

订购信息

产品名称产品编号规格价格数量收藏夹

Fibronectin 抗体 (IST-1)

sc-59824
200 µg/ml
CNY2422.00

Fibronectin (IST-1): m-IgG Fc BP-HRP 套装

sc-539142
200 µg Ab; 10 µg BP
CNY2715.00

Fibronectin (IST-1): m-IgG1 BP-HRP 套装

sc-541290
200 µg Ab; 20 µg BP
CNY2715.00

I am using Fibronectin (IST-1): sc-59824 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Professor Griffin
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_10, d_24, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_zh_CN, sid_59824, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 92ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by Germaine from Strong WB monoclonalGreat strong distinct clear and clean bands for WB on U-87 MG, HT-1080 whole cell lysates and human platelet extract
Date published: 2017-01-18
Rated 5 out of 5 by JL from Consistently produces good signal with humanConsistently produces good signal with human platelet extract in Western Blot. -SCBT QC
Date published: 2015-01-07
Rated 4 out of 5 by CJ from FFPE of human skin showed cytoplasmic stainingFFPE of human skin showed cytoplasmic staining of epidermal cells and extracellular staining of dermal connective tissue. -SCBT QC
Date published: 2014-02-04
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_59824, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
Fibronectin 抗体 (IST-1) is rated 4.7 out of 5 by 3.
  • y_2026, m_10, d_24, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_59824, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 104ms
  • REVIEWS, PRODUCT