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Fibronectin 抗体 (Fn-4): sc-53286

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说明书
  • Fibronectin 抗体 Fn-4 是小鼠单克隆 IgG1,提供 200 µg/ml
  • 免疫human物种的Fibronectin
  • 推荐用于 human 来源的cellular and plasma Fibronectin WB 和 IP检测
  • 看 Fibronectin (EP5): sc-8422,可查看有标记的 Fibronectin 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Fibronectin 抗体 (Fn-4)的首选二抗检测试剂的鉴定。这项工作正在进行中。
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    纤维连接蛋白是一种细胞外基质糖蛋白,存在于大多数细胞表面、细胞外液和血浆中。它是一种高分子量的异二聚体蛋白,最初被发现是病毒转化细胞表面缺失的蛋白质,已被证明参与各种功能,包括细胞粘附、细胞运动和伤口愈合。选择性剪接和糖基化产生了几种不同形式的纤维连接蛋白,其中一些表现出有限的组织分布或与恶性肿瘤有关。已经证明,肌成纤维细胞表型的形成与迪皮特伦病中糖基化纤维连接蛋白和纤维连接蛋白剪接变异体的发生有关。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Fibronectin 抗体 (Fn-4) 参考文献:

    1. 纤连蛋白基质组装分析  |  Wierzbicka-Patynowski, I., et al. 2004. Curr Protoc Cell Biol. Chapter 10: Unit 10.12. PMID: 18228438
    2. 体外细胞衰老过程中纤维粘连蛋白表达增加:与细胞面积增加有关  |  Kumazaki, T., et al. 1991. Exp Cell Res. 195: 13-9. PMID: 2055262
    3. 纤连蛋白改变纤维蛋白基质的形成速度和结构  |  Ramanathan, A. and Karuri, N. 2014. Biochem Biophys Res Commun. 443: 395-9. PMID: 24309108
    4. 原生纤连蛋白纤维的分子结构。  |  Früh, SM., et al. 2015. Nat Commun. 6: 7275. PMID: 26041410
    5. 纤维粘连蛋白的自体分泌抑制乳腺癌转移。  |  Shinde, A., et al. 2018. Mol Cancer Res. 16: 1579-1589. PMID: 29934326
    6. 血浆纤维粘连蛋白和纤维粘连蛋白治疗败血症和重症。  |  Grossman, JE. 1987. Rev Infect Dis. 9 Suppl 4: S420-30. PMID: 3326138
    7. 由纤维粘连蛋白和 IL-1β 驱动的正反馈回路可维持乳腺癌的炎症微环境。  |  Tunali, G., et al. 2023. Breast Cancer Res. 25: 27. PMID: 36922898
    8. 人类皮肤成纤维细胞收缩胶原格的纤连蛋白依赖性。  |  Gillery, P., et al. 1986. Exp Cell Res. 167: 29-37. PMID: 3758208
    9. 对纤维粘连蛋白在细菌和微聚集体中的作用的批判性评估  |  Doran, JE. 1983. Vox Sang. 45: 337-48. PMID: 6314664
    10. 多孔动物中的纤连蛋白样蛋白:在细胞聚集中的作用  |  Labat-Robert, J., et al. 1981. Proc Natl Acad Sci U S A. 78: 6261-5. PMID: 7031644

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Fibronectin 抗体 (Fn-4)

    sc-53286
    200 µg/ml
    CNY2422.00

    We are looking for anti-fibronectin antibody that recognizes the 70-kDa N-terminal portion of human fibronectin, and preferably is not conformation specific (to be used for WB). Any suggestions?

    Asked by: KlaraB
    Thank you for your question. We have not specifically evaluated this antibody for reactivity with the 70 kDa N-terminal fragment of human fibronectin. Please contact us for Technical Support and we can help you select some potential antibodies for your research.
    Answered by: Technical Support
    Date published: 2019-07-13

    What is the recommended storage condition for Fibronectin (Fn-4): sc-53286?

    Asked by: Randy McDonald
    Thank you for your question. We recommend storing the antibody at 4° C.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 3 out of 5 by SH from Successfully used in IP with Hep G2 cellsSuccessfully used in IP with Hep G2 cells. -SCBT QC
    Date published: 2013-12-04
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    Fibronectin 抗体 (Fn-4) is rated 3.0 out of 5 by 1.
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