Date published: 2025-9-7

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FANCF 抗体 (G-4): sc-271397

5.0(2)
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说明书
  • FANCF抗体(G-4)是小鼠单克隆IgG2b (kappa轻链),规格为200 µg/ml
  • 免疫human物种的FANCF的氨基酸41-350
  • 推荐用于 mouse, rat 和 human 来源的FANCF WB, IP, IF 和 ELISA检测
  • 2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是FANCF Antibody (G-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与FANCF Antibody (G-4) 打包提供(请参阅下面的订购信息)。

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    関連項目

    范可尼贫血(FA)是一种常染色体隐性遗传病,以骨髓衰竭、出生缺陷和染色体不稳定性为特征。在细胞水平上,FA的特征是自发性染色体断裂和对DNA交联剂的独特超敏感性。目前已经确定了至少8个互补群(A-G),并克隆了6个FA基因(对应于A、C、D2、E、F和G亚型)。FA蛋白缺乏能指向分子功能的序列同源性或基序。FANC(范可尼贫血互补群)蛋白的磷酸化被认为对FA通路的功能很重要。FA蛋白由6个克隆的FA基因(FANCA、FANCC、FANCD2、FANCE、FANCF和FANCG)编码,并在一个共同通路中协作,最终导致FANCD2蛋白的单泛素化及FANCD2和BRCA1蛋白在核焦点中的共定位。FANCF蛋白是FANCD2激活所必需的,并且似乎可以稳定该复合物的其他亚基。人类FANCF基因定位于11p15染色体,编码一种与原核RNA结合蛋白ROM具有同源性的核蛋白。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    FANCF 抗体 (G-4)

    sc-271397
    200 µg/ml
    RMB2377.00

    FANCF (G-4): m-IgGκ BP-HRP 套装

    sc-534947
    200 µg Ab; 40 µg BP
    RMB2662.00

    FANCF (G-4): m-IgG2b BP-HRP 套装

    sc-549319
    200 µg Ab; 10 µg BP
    RMB2662.00

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with FANCF (G-4): sc-271397?

    Asked by: Trav11
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-02-27
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    Rated 5 out of 5 by from Produced positive Western Blot data of FANCFProduced positive Western Blot data of FANCF expression in HeLa and NIH/3T3 whole cell lysates. -SCBT QC
    Date published: 2015-04-04
    Rated 5 out of 5 by from Produced positive Western Blot data of FANCFProduced positive Western Blot data of FANCF expression in non-transfected and human FANCF transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-04-29
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    FANCF 抗体 (G-4) is rated 5.0 out of 5 by 2.
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