Date published: 2025-9-7
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
Factor H Antibody (C18/3) - Immunohistochemistry - Image 287069
因子 H 抗体 (C18/3): sc-47685. 对福尔马林固定, 石蜡包埋的人类卵巢组织进行免疫过氧化物酶染色, 显示卵巢基质细胞的细胞质染色和血管中的血浆染色.
Factor H Antibody (C18/3) - Immunohistochemistry - Image 287069
因子 H 抗体 (C18/3): sc-47685. 对福尔马林固定, 石蜡包埋的人类卵巢组织进行免疫过氧化物酶染色, 显示卵巢基质细胞的细胞质染色和血管中的血浆染色.
Factor H Antibody (C18/3) - Western Blotting - Image 20455
因子 H 抗体 (C18/3): sc-47685. 人 PBL 全细胞裂解液 (A) 和人重组因子 H (B) 中因子 H 表达的 Western 印迹分析.
Factor H Antibody (C18/3) - Western Blotting - Image 396693
因子 H 抗体 (C18/3): sc-47685. 人血浆提取物中因子 H 的 Western 印迹分析.
因子 H 抗体 (C18/3): sc-47685. 对福尔马林固定, 石蜡包埋的人类卵巢组织进行免疫过氧化物酶染色, 显示卵巢基质细胞的细胞质染色和血管中的血浆染色.

Factor H 抗体 (C18/3): sc-47685

4.4(7)
寫評論提問

说明书
  • Factor H 抗体 C18/3 是小鼠单克隆 IgG1 κ，Factor H抗体, 在4篇文献中引用，规格为200 µg/ml
  • 从human血清中纯化的抗补体蛋白因子H
  • Factor H 抗体 (C18/3) 推荐用于WB, IP, IF 和 IHC(P)，检测human 来源的 Factor H
  • 抗Factor H抗体（C18/3）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Factor H (C18/3): sc-47685的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG1 BP-HRP 是 Factor H 抗体 (C18/3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Factor H 抗体 (C18/3) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 Coagulation Factor 抗体 包括 Factor B, Factor H, Factor I, Factor IX, Factor V, Factor VII, Factor VIII, Factor X, Factor XI和Factor XII

因子H抗体（C18/3）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和石蜡包埋切片免疫组织化学（IHCP）检测人类源性因子H蛋白。H因子（C18/3）抗体有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。H因子蛋白在调节替代补体途径中起着至关重要的作用，该途径对于免疫反应和维持体内平衡至关重要。H因子是一种血清糖蛋白，由1213个氨基酸组成，分为20个短的重复序列（SCR），具有多种功能，包括作为因子I的辅助因子，使C3b失活。H因子与细胞整合素受体和糖胺聚糖相互作用，其重要性不仅限于补体系统。H因子缺乏与急性肾病有关，这凸显了其在免疫调节和疾病病理学中的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Factor H 抗体 (C18/3) 参考文献:

  1. H 蛋白因子家族  |  Zipfel, PF., et al. 1999. Immunopharmacology. 42: 53-60. PMID: 10408366
  2. 补体因子 H：包含整个 fH, fHR-1 和 fHR-3 基因的 221 kb 人类基因组 DNA 的序列分析。  |  Male, DA., et al. 2000. Mol Immunol. 37: 41-52. PMID: 10781834
  3. 年龄相关性黄斑变性中的补体因子H多态性。  |  Klein, RJ., et al. 2005. Science. 308: 385-9. PMID: 15761122
  4. 补体因子 H mRNA 表达分析：地塞米松和 IFN-gamma 可提高 L 细胞中 H 的水平。  |  Muñoz-Cánoves, P., et al. 1989. Biochemistry. 28: 9891-7. PMID: 2533512
  5. 因子H相关蛋白决定补体激活表面。  |  Józsi, M., et al. 2015. Trends Immunol. 36: 374-84. PMID: 25979655
  6. 人类补体因子 H 的完整氨基酸序列。  |  Ripoche, J., et al. 1988. Biochem J. 249: 593-602. PMID: 2963625
  7. 普鲁丁和因子H在疾病中的作用。  |  Cortes, C., et al. 2022. Adv Immunol. 153: 1-90. PMID: 35469595
  8. 因子H相关蛋白调节肾脏细胞的补体激活。  |  Renner, B., et al. 2022. Kidney Int. 102: 1331-1344. PMID: 36063874
  9. 补体C3的细胞自主调节受因子H的限制，限制巨噬细胞吞噬作用，加剧动脉粥样硬化。  |  Kiss, MG., et al. 2023. Immunity. 56: 1809-1824.e10. PMID: 37499656
  10. 补体因子H通过上调类风湿性关节炎中的EIF3C来减弱TNF-α诱导的炎症。  |  Jia, Y., et al. 2023. J Transl Med. 21: 846. PMID: 37996918
  11. 针对补体控制蛋白 H 因子（β 1 H）的单克隆抗体。  |  Sim, E., et al. 1983. Biosci Rep. 3: 1119-31. PMID: 6199050
  12. 与溶血性尿毒症综合征相关的人类补体因子 H 缺乏症。  |  Rougier, N., et al. 1998. J Am Soc Nephrol. 9: 2318-26. PMID: 9848786

订购信息

产品名称产品编号规格价格数量收藏夹

Factor H 抗体 (C18/3)

sc-47685
200 µg/ml
RMB2377.00

Factor H (C18/3): m-IgG Fc BP-HRP 套装

sc-526730
200 µg Ab; 10 µg BP
RMB2662.00

Factor H (C18/3): m-IgG1 BP-HRP 套装

sc-532103
200 µg Ab; 20 µg BP
RMB2662.00

Factor H 抗体 (C18/3) AC

sc-47685 AC
500 µg/ml, 25% agarose
RMB3129.00

Factor H 抗体 (C18/3) HRP

sc-47685 HRP
200 µg/ml
RMB2377.00

Factor H 抗体 (C18/3) FITC

sc-47685 FITC
200 µg/ml
RMB2482.00

Factor H 抗体 (C18/3) PE

sc-47685 PE
200 µg/ml
RMB2580.00

Factor H 抗体 (C18/3) Alexa Fluor® 488

sc-47685 AF488
200 µg/ml
RMB2685.00

Factor H 抗体 (C18/3) Alexa Fluor® 546

sc-47685 AF546
200 µg/ml
RMB2685.00

Factor H 抗体 (C18/3) Alexa Fluor® 594

sc-47685 AF594
200 µg/ml
RMB2685.00

Factor H 抗体 (C18/3) Alexa Fluor® 647

sc-47685 AF647
200 µg/ml
RMB2685.00

Factor H 抗体 (C18/3) Alexa Fluor® 680

sc-47685 AF680
200 µg/ml
RMB2685.00

Factor H 抗体 (C18/3) Alexa Fluor® 790

sc-47685 AF790
200 µg/ml
RMB2685.00

Which Factor H can apply for the LF?

Asked by: chenjiaying
Thank you for your question . For assistance please contact technical service by emailing [email protected].
Answered by: BlakeJ
Date published: 2023-04-11

Has the epitope on factor H been mapped for this monoclonal antibody? I'm looking for an antibody the recognizes repeats 1-4.

Asked by: Eric Krukonis
Thank you for your question. The exact epitope recognized by this mouse monoclonal antibody has not yet been determined.
Answered by: Technical Support
Date published: 2019-01-24

Can Factor H (C18/3) sc-47685 antibody be used on an automated IHC stainer, such as Ventana Benchmark Ultra? Do you have any recommended protocols?

Asked by: jdb7928
Thank you for your question. We have not tested this antibody, sc-47685, on an automatic stainer, so I do not have any information regarding that. If you would like to try a sample of this antibody, please contact Technical Service by phone, (800)-457-3801 option 2, email <[email protected]>, or by live chat directly on our website, www.scbt.com, and we would be glad to send that to you!
Answered by: Tech Service
Date published: 2017-06-27

Can Factor H (C18/3): sc-47685 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Factor H (C18/3): sc-47685 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_9, d_6, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_4
  • loc_zh_CN, sid_47685, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 111ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Great antibodyI am very happy with this antibody we bought last month
Date published: 2019-09-03
Rated 5 out of 5 by from Works for IHCReceived sample for testing. Worked in FFPE human for IHC. Citrate for retrieval. Incubated overnight at 4C at 10ug/mL.
Date published: 2017-11-13
Rated 3 out of 5 by from Did't work in IF of rat brain frozen sliceThis monocloned antibody did't work in the rat brain frozen slice ,even that was recovered by heat.
Date published: 2017-07-13
Rated 3 out of 5 by from 在大鼠的脑切片免疫荧光实验中没有阳性结合在大鼠脑冰冻切片（包括用热修复）中，1：25使用该抗体进行免疫荧光实验，没有特异性结合。然后再人源细胞系SY5Y细胞中也进行免疫荧光实验，结合的程度并没有33156好。
Date published: 2017-07-13
Rated 5 out of 5 by from This antibody works wellThis antibody works well
Date published: 2015-05-28
Rated 5 out of 5 by from Produced wonderful immunoperoxidase cytoplasmicProduced wonderful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human ovary tissue. -SCBT QC
Date published: 2015-05-13
Rated 5 out of 5 by from Good specificity in WB in human whole cellGood specificity in WB in human whole cell lysate and human recombinant Factor H. -SCBT QC
Date published: 2015-03-27
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_47685, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 18ms
  • REVIEWS, PRODUCT
Factor H 抗体 (C18/3) is rated 4.4 out of 5 by 7.
  • y_2025, m_9, d_6, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_7
  • loc_zh_CN, sid_47685, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 120ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。