Date published: 2025-9-6

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ERK 1 抗体 (G-12): sc-376852

4.5(2)
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说明书
  • ERK 1抗体(G-12)是小鼠单克隆IgG1 κ, 在8篇文献中引用,规格为200 µg/ml
  • 推荐用于 mouse, rat, human, chicken 和 frog 来源的ERK 1 p44 WB, IP, IF 和 ELISA检测
  • 看 ERK 1 (G-8): sc-271269,可查看有标记的 ERK 1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是ERK 1 Antibody (G-12) for WB applications. 的首选辅助检测试剂,这些试剂现与ERK 1 Antibody (G-12) 打包提供(请参阅下面的订购信息)。

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有丝分裂原激活的蛋白激酶(MAPK)信号通路涉及两个密切相关的MAP激酶,即细胞外信号相关激酶1(ERK 1,p44)和2(ERK 2,p42)。生长因子、类固醇激素、G蛋白偶联受体配体和神经递质可以启动MAPK信号通路。ERK 1和ERK 2的激活需要上游激酶如MAP激酶激酶(MEK)、MEK激酶和Raf-1的磷酸化。ERK 1和ERK 2的磷酸化可以发生在包含苏氨酸-谷氨酸-酪氨酸基序的一致基序内映射的特定酪氨酸和苏氨酸位点。ERK的激活导致与其他ERKs的二聚化,并随后定位到细胞核。活性ERK二聚体磷酸化核蛋白上的丝氨酸和苏氨酸残基,并影响一系列反应,包括增殖、分化、转录调控和发育。人类ERK 1基因映射到染色体16p11.2,并编码一个由379个氨基酸组成的蛋白质,与ERK 2有83%的序列同一性。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

ERK 1 抗体 (G-12)

sc-376852
200 µg/ml
RMB2377.00

ERK 1 (G-12): m-IgG Fc BP-HRP 套装

sc-540654
200 µg Ab; 10 µg BP
RMB2662.00

ERK 1 (G-12): m-IgG1 BP-HRP 套装

sc-542273
200 µg Ab; 20 µg BP
RMB2662.00

ERK 1 (G-12) 中和勝肽

sc-376852 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-376852 P appropriate for?

Asked by: Germaine
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Published with this antibody using mousePublished with this antibody using mouse colon tissue for immunoblot analysis -SCBT Publication Review
Date published: 2015-04-14
Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2013-06-29
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ERK 1 抗体 (G-12) is rated 4.5 out of 5 by 2.
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