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ephrin-A3 抗体 (G-11): sc-398331

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说明书
  • ephrin-A3抗体(G-11)是小鼠单克隆mouse IgG1 κ (kappa轻链),规格为200 µg/ml
  • 免疫原氨基酸序列149-238位于human物种的ephrin-A3的C-terminus
  • 推荐用于 mouse, rat 和 human 来源的ephrin-A3 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是ephrin-A3 Antibody (G-11) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与ephrin-A3 Antibody (G-11) 打包提供(请参阅下面的订购信息)。

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    関連項目

    Eph亚家族受体代表了迄今为止鉴定的最大的受体蛋白激酶组。有越来越多的证据表明,它们参与中枢神经系统功能及其发育。Eph受体的配体包括ephrin-A1(LERK-1/B61),被鉴定为EphA2(Eck)受体的配体;ephrin-A2(ELF-1),被鉴定为EphA3和EphA4(Sek)受体的配体;ephrin-A3(LERK-3),被鉴定为EphA5(Ehk1)和EphA3(Hek)受体的配体;ephrin-A4(LERK-4),被鉴定为EphA3受体的配体;ephrin-A5(AL-1),被鉴定为EphA5(REK7)的配体;ephrin-B1(LERK-2),被鉴定为EphB1(Elk)和EphB2(Cek5)受体的配体;ephrin-B2(LERK-5),被鉴定为EphB1、EphB3(Cek10)和EphB2受体的配体;以及ephrin-B3(LERK-8),被鉴定为EphB1的配体。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    ephrin-A3 抗体 (G-11) 参考文献:

    1. ephrin-A3和ephrin-A5剪接变体的鉴定和特征描述。  |  Lai, KO., et al. 1999. FEBS Lett. 458: 265-9. PMID: 10481078
    2. Ephrin-A3 不仅能增加新生小鼠毛囊的密度,还能加速新生小鼠的生长发育。  |  Yamada, Y., et al. 2008. J Dermatol Sci. 52: 178-85. PMID: 18640011
    3. 硫酸肝素调节ephrin-A3/EphA受体信号传导。  |  Irie, F., et al. 2008. Proc Natl Acad Sci U S A. 105: 12307-12. PMID: 18715996
    4. 神经胶质ephrin-A3调节海马树突棘形态和谷氨酸转运  |  Carmona, MA., et al. 2009. Proc Natl Acad Sci U S A. 106: 12524-9. PMID: 19592509
    5. 神经元与神经胶质细胞通过 EphA4/ephrin-A3 进行交流,通过神经胶质细胞谷氨酸转运调节 LTP。  |  Filosa, A., et al. 2009. Nat Neurosci. 12: 1285-92. PMID: 19734893
    6. Ephrin-A3可抑制Wnt信号,从而控制视网膜干细胞的有效性。  |  Fang, Y., et al. 2013. Stem Cells. 31: 349-59. PMID: 23165658
    7. Ephrin-A3能在出生后的发育和神经再支配过程中促进并维持慢肌纤维的特性。  |  Stark, DA., et al. 2015. J Cell Biol. 211: 1077-91. PMID: 26644518
    8. miR-210, E2F3和ephrin A3在血管肉瘤细胞增殖中的作用  |  Nakashima, S., et al. 2017. Eur J Dermatol. 27: 464-471. PMID: 28739548
    9. 老年ephrin-A3-/-小鼠的肌肉纤维类型分布正常,而以前这些小鼠缺乏大部分慢肌纤维。  |  Arpke, RW., et al. 2023. Am J Physiol Cell Physiol. 324: C718-C727. PMID: 36717102
    10. 昼夜节律机制对小鼠EphA4、Ephrin-B2和Ephrin-A3基因的转录物调控。  |  Ballester Roig, MN., et al. 2023. Chronobiol Int. 40: 983-1003. PMID: 37551686

    订购信息

    产品名称产品编号规格价格数量收藏夹

    ephrin-A3 抗体 (G-11)

    sc-398331
    200 µg/ml
    RMB2377.00

    ephrin-A3 (G-11): m-IgG Fc BP-HRP 套装

    sc-538421
    200 µg Ab; 10 µg BP
    RMB2662.00

    ephrin-A3 (G-11): m-IgGκ BP-HRP 套装

    sc-536033
    200 µg Ab; 40 µg BP
    RMB2662.00

    I need to use an antibody to detect the protein in samples of porcine origin. Do you know if ephrin-A3 (G-11): sc-398331 mouse monoclonal antibody will work?

    Asked by: jenniferc
    Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Great Western blot data of ephrinGreat Western blot data of ephrin-A3 expression in non-transfected and human ephrin-A3 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-02-11
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    ephrin-A3 抗体 (G-11) is rated 5.0 out of 5 by 1.
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