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Endoglin/CD105 抗体 (MJ7/18): sc-18893

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说明书
  • Endoglin/CD105 抗体 MJ7/18 是大鼠单克隆 IgG2a, 在13篇文献中引用,提供 200 µg/ml
  • 针对发炎的mouse皮肤组织
  • 推荐用于 mouse, rat 和 human 来源的Endoglin WB, IP, IF 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 Endoglin/CD105 (P3D1): sc-18838,可查看有标记的 Endoglin/CD105 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Endoglin/CD105 抗体 (MJ7/18)的首选二抗检测试剂的鉴定。这项工作正在进行中。
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関連項目

内皮素抗体(MJ7/18)是一种鼠单克隆IgG2a抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和流式细胞术(FCM)等方法检测小鼠、大鼠和人类样本中的内皮素。内皮素作为转化生长因子-β(TGF-β)超家族配体的共受体,在内皮细胞功能和血管生成中发挥着至关重要的作用。内皮素调节血管形成和修复的信号通路,是维持血管完整性的关键因素。内皮素基因突变与遗传性出血性毛细血管扩张症(HHT)有关,这是一种以血管异常形成和出血风险增加为特征的疾病。通过了解内皮素的功能及其与TGF-β配体的相互作用,研究人员可以深入了解血管疾病的潜在机制,并制定潜在的治疗策略。内皮素单克隆抗体(MJ7/18)是研究这些过程和增进我们对血管生物学认识的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Endoglin/CD105 抗体 (MJ7/18) 参考文献:

  1. 血管生成和血管疾病中的内皮素。  |  ten Dijke, P., et al. 2008. Angiogenesis. 11: 79-89. PMID: 18283546
  2. 可溶性内皮素、高胆固醇血症和内皮功能障碍。  |  Rathouska, J., et al. 2015. Atherosclerosis. 243: 383-8. PMID: 26520890
  3. 内皮素在缺血再血管化中的作用。  |  Núñez-Gómez, E., et al. 2017. Angiogenesis. 20: 1-24. PMID: 27943030
  4. 基于内皮素的生物疗法在治疗血管生成依赖性疾病中的应用。  |  Ollauri-Ibáñez, C., et al. 2017. Expert Opin Biol Ther. 17: 1053-1063. PMID: 28656781
  5. 内皮素和alk1作为遗传性出血性毛细血管扩张的治疗靶点。  |  Ruiz-Llorente, L., et al. 2017. Expert Opin Ther Targets. 21: 933-947. PMID: 28796572
  6. 内皮素在心肌纤维化中的作用。  |  Shyu, KG. 2017. Acta Cardiol Sin. 33: 461-467. PMID: 28959097
  7. 胶质母细胞瘤中的内皮素和TGF-β信号传导。  |  Burghardt, I., et al. 2021. Cell Tissue Res. 384: 613-624. PMID: 33471197
  8. 内皮素在肝细胞癌中的作用。  |  Jeng, KS., et al. 2021. Int J Mol Sci. 22: PMID: 33809908
  9. 内皮素及其可溶性形式在子痫前期发病机理中的作用。  |  Margioula-Siarkou, G., et al. 2022. Mol Cell Biochem. 477: 479-491. PMID: 34783962
  10. 人内皮素在病理生理学中新的血管作用。  |  Rossi, E. and Bernabeu, C. 2023. J Thromb Haemost. 21: 2327-2338. PMID: 37315795

订购信息

产品名称产品编号规格价格数量收藏夹

Endoglin/CD105 抗体 (MJ7/18)

sc-18893
200 µg/ml
CNY2422.00

Endoglin/CD105 抗体 (MJ7/18) FITC

sc-18893 FITC
200 µg/ml
CNY2527.00

Endoglin/CD105 抗体 (MJ7/18) PE

sc-18893 PE
200 µg/ml
CNY2625.00

Can Endoglin (MJ7/18): sc-18893 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: cjMara
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, Endoglin (MJ7/18): sc-18893 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by JT from WB with mouse kidney extractsWB with mouse kidney extracts. -SCBT Publication Review
Date published: 2015-05-27
Rated 3 out of 5 by LM from IF with murine uterus sectionsIF with murine uterus sections. -SCBT Publication Review
Date published: 2015-05-26
Rated 4 out of 5 by JM from Published Flow Cytometry data using murinePublished Flow Cytometry data using murine embryonic endothelial cells. -SCBT Publication Review
Date published: 2015-05-16
Rated 3 out of 5 by QZ from Decent immunofluorescence membrane stainingDecent immunofluorescence membrane staining in methanol-fixed JAR cells. -SCBT QC
Date published: 2015-03-31
Rated 3 out of 5 by TO from Used for immunohistochemical analysis ofUsed for immunohistochemical analysis of paraffin embedded human testes sections. -SCBT Publication Review
Date published: 2015-02-24
Rated 3 out of 5 by MC from Satisfactory FCM data of mouse peripheralSatisfactory FCM data of mouse peripheral blood leukocytes. -SCBT QC
Date published: 2013-03-15
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Endoglin/CD105 抗体 (MJ7/18) is rated 3.3 out of 5 by 6.
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