Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

EGFR 抗体 (F-9): sc-377073

4.5(4)
寫評論提問

说明书
  • EGFR抗体(F-9)是小鼠单克隆IgG1 κ, 在4篇文献中引用,规格为200 µg/ml
  • 特定于human起源的EGFR的C-terminal细胞质域内氨基酸1131-1169之间的表位图谱
  • 推荐用于 human 来源的EGFR WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 EGFR (A-10): sc-373746,可查看有标记的 EGFR 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 EGFR 抗体 (F-9) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与EGFR 抗体 (F-9) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

表皮生长因子受体家族包括几种相关的受体酪氨酸激酶,它们在多种癌症中经常被过度表达。该受体家族的成员包括EGFR(HER1)、Neu(ErbB-2,HER2)、ErbB-3(HER3)和ErbB-4(HER4),它们在配体结合后形成同二聚体或异二聚体。EGFR基因产物中的外显子经常被删除或复制,分别产生缺失突变体(DM)或串联重复突变体(TDM),这些突变体以不同的分子量检测到。EGFR结合多种配体,包括表皮生长因子(EGF)、转化生长因子α(TGFα)、双调蛋白和肝素结合-EGF(HB-EGF)。配体结合通过网格蛋白包被的凹坑促进EGFR的内化,并随后响应其内在酪氨酸激酶而降解。EGFR参与器官形态发生和组织的维持和修复,但EGFR的上调与肿瘤进展有关。EGFR的致癌作用包括启动DNA合成、增强细胞生长、侵袭和转移。EGFR的缺失导致癌症细胞周期阻滞、凋亡或去分化,提示EGFR可能是一种有效的治疗靶点。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

EGFR 抗体 (F-9)

sc-377073
200 µg/ml
RMB2377.00

EGFR (F-9): m-IgG Fc BP-HRP 套装

sc-540692
200 µg Ab; 10 µg BP
RMB2662.00

EGFR (F-9): m-IgG1 BP-HRP 套装

sc-542301
200 µg Ab; 20 µg BP
RMB2662.00

EGFR (F-9) 中和勝肽

sc-377073 P
100 µg/0.5 ml
RMB511.00

What application is the blocking peptide sc-377073 P appropriate for?

Asked by: Germaine
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24

Hi there, I'm Dr. Chang from UBIA, Taiwan, and seeking anti-human EGFR Ab, but no cross-reactivity to mouse EGFR. And I will apply in WB and IHC-p experiment.If you have any suitable product fits my request, please don't hesitate to contact with me. Thank

Asked by: Morris
Thank you for your question. Yes, we would recommend using our mouse monoclonal, EGFR Antibody (F-9): sc-377073. This antibody has been tested by Western blot in samples of mouse and human origin, and only shows reactivity with human EGFR.
Answered by: Technical Support
Date published: 2017-01-06
  • y_2025, m_8, d_31, h_8CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_377073, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 107ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Worked well in WB at 1:200 dilutionWorked well in WB at 1:200 dilution.
Date published: 2015-06-24
Rated 5 out of 5 by from Good signal strength in HeLa and BTGood signal strength in HeLa and BT-20 whole cell lysates. -SCBT QC
Date published: 2015-02-27
Rated 5 out of 5 by from Works well for IF applicationsWorks well for IF applications, membrane staining in MeOH fixed HeLa cells. -SCBT QC
Date published: 2015-01-05
Rated 3 out of 5 by from Detected signal at correct molecular weightDetected signal at correct molecular weight with some background in EGF treated A-431 whole cell lysate. -SCBT QC
Date published: 2013-08-07
  • y_2025, m_8, d_31, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_377073, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
EGFR 抗体 (F-9) is rated 4.5 out of 5 by 4.
  • y_2025, m_8, d_31, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_377073, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 134ms
  • REVIEWS, PRODUCT