Date published: 2025-12-10

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EBP1 抗体 (C-11): sc-393114

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说明书
  • EBP1 抗体 C-11 是小鼠单克隆 IgG1 κ,EBP1抗体, 在3篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列1-300位于human物种的EBP1的N-terminus
  • EBP1 抗体 (C-11) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 EBP1; 也和以下物种反应,包括: 和 equine, canine and bovine
  • 抗EBP1抗体(C-11)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是EBP1 Antibody (C-11) 适用于 WB 和 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与EBP1 Antibody (C-11) 打包提供(请参阅下面的订购信息)。

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関連項目

EBP1抗体(C-11)是一种IgG1 κ型小鼠单克隆EBP1抗体(也称为EBP1抗体),可通过WB, IP, IF, IHC(P) 和 ELISA检测到源自小鼠、大鼠和人类的EBP1蛋白。EBP1抗体(C-11)既有非偶联型抗EBP1抗体形式,也有多种偶联型抗EBP1抗体形式,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。EBP1(ErbB3结合蛋白1),也称为PA2G4(增殖相关2G4)、p38-2G4或HG4-1,是肽酶M24C家族的成员,作为RNA结合蛋白参与细胞增殖和分化过程。它在多种细胞系中表达,包括多种肿瘤细胞系,并定位于细胞质中。经神经调节蛋白-1(heregulin)处理后,EBP1转移至细胞核。EBP1是核糖体前核糖核蛋白复合物的组成部分,参与核糖体组装并调节rRNA加工的后期步骤。此外,EBP1与ErbB-3相互作用,并可能通过调节神经调节蛋白-1(heregulin)的作用而作为ErbB-3介导的信号转导通路的调节剂。EBP1还与组蛋白去乙酰化酶(HDACs)相关,作为细胞周期调控基因的转录共抑制因子发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

EBP1 抗体 (C-11) 参考文献:

  1. ErbB3结合蛋白Ebp1与Sin3A相互作用,抑制E2F1和AR介导的转录。  |  Zhang, Y., et al. 2005. Nucleic Acids Res. 33: 6024-33. PMID: 16254079
  2. 确定 Ebp1 是细胞质 bcl-2 mRNP(信使核糖核蛋白颗粒)复合物的组成部分。  |  Bose, SK., et al. 2006. Biochem J. 396: 99-107. PMID: 16396631
  3. Ebp1 是一种与核糖体相关的 dsRNA 结合蛋白,可调节 eIF2alpha 的磷酸化。  |  Squatrito, M., et al. 2006. Biochem Biophys Res Commun. 344: 859-68. PMID: 16631606
  4. ErbB3结合蛋白Ebp1基因转移抑制唾液腺样囊性癌的生长和转移  |  Yu, Y., et al. 2007. Int J Cancer. 120: 1909-13. PMID: 17266032
  5. 宿主因子 Ebp1:流感病毒转录酶的选择性抑制剂。  |  Honda, A., et al. 2007. Genes Cells. 12: 133-42. PMID: 17295834
  6. 作为免疫疗法靶点的 ErbB-3 结合蛋白-1 的鉴定和特征描述。  |  Santegoets, SJ., et al. 2007. J Immunol. 179: 2005-12. PMID: 17641068
  7. Ebp1 的晶体结构揭示了一个蛋氨酸氨肽酶折叠作为多种相互作用的结合平台。  |  Kowalinski, E., et al. 2007. FEBS Lett. 581: 4450-4. PMID: 17765895
  8. 增殖相关蛋白 Ebp1 的表达, 纯化, 结晶和初步晶体学分析。  |  Kowalinski, E., et al. 2007. Acta Crystallogr Sect F Struct Biol Cryst Commun. 63: 768-70. PMID: 17768350
  9. Ebp1 介导的细胞生长抑制需要丝氨酸 363 磷酸化。  |  Akinmade, D., et al. 2007. Int J Oncol. 31: 851-8. PMID: 17786317
  10. ERBB3结合蛋白1(EBP1)在唾液腺样囊性癌中的表达及其临床病理相关性  |  Sun, J., et al. 2012. BMC Cancer. 12: 499. PMID: 23110497
  11. 乳腺癌中 PAK1-EBP1 信号通路对他莫昔芬敏感性的调控  |  Ghosh, A., et al. 2013. Br J Cancer. 108: 557-63. PMID: 23361053
  12. HIV-1 病毒蛋白 R 下调胶质母细胞瘤 U87MG 细胞中的 Ebp1 并稳定 p53  |  Zhang, S., et al. 2014. Clin Transl Oncol. 16: 293-300. PMID: 23828502

订购信息

产品名称产品编号规格价格数量收藏夹

EBP1 抗体 (C-11)

sc-393114
200 µg/ml
RMB2377.00

EBP1 (C-11): m-IgGκ BP-HRP 套装

sc-523809
200 µg Ab, 40 µg BP
RMB2662.00

EBP1 (C-11): m-IgG1 BP-HRP 套装

sc-533611
200 µg Ab; 20 µg BP
RMB2662.00

EBP1 抗体 (C-11) AC

sc-393114 AC
500 µg/ml, 25% agarose
RMB3129.00

EBP1 抗体 (C-11) HRP

sc-393114 HRP
200 µg/ml
RMB2377.00

EBP1 抗体 (C-11) FITC

sc-393114 FITC
200 µg/ml
RMB2482.00

EBP1 抗体 (C-11) PE

sc-393114 PE
200 µg/ml
RMB2580.00

EBP1 抗体 (C-11) Alexa Fluor® 488

sc-393114 AF488
200 µg/ml
RMB2685.00

EBP1 抗体 (C-11) Alexa Fluor® 546

sc-393114 AF546
200 µg/ml
RMB2685.00

EBP1 抗体 (C-11) Alexa Fluor® 594

sc-393114 AF594
200 µg/ml
RMB2685.00

EBP1 抗体 (C-11) Alexa Fluor® 647

sc-393114 AF647
200 µg/ml
RMB2685.00

EBP1 抗体 (C-11) Alexa Fluor® 680

sc-393114 AF680
200 µg/ml
RMB2685.00

EBP1 抗体 (C-11) Alexa Fluor® 790

sc-393114 AF790
200 µg/ml
RMB2685.00

Can he distinguish between p48 and p42, or is it that he can recognize both?

Asked by: Anonymous
Thank you for your question. EBP1 Antibody (C-11) is recommended for detection of EBP1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. If you have any other question, please contact our Technical Service Department. Our Asian Technical Service team is available at (+86) 021-60936350 or [email protected] or by live chat on our website.
Answered by: Sen Li
Date published: 2025-10-24

Can EBP1 (C-11): sc-393114 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Professor Griffin
Thank you for your question. Yes, EBP1 (C-11): sc-393114 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from goodthis antibody is very good,for western blotting,with 1:2000 dilution,the band is clear
Date published: 2017-02-16
Rated 5 out of 5 by from Robust signal in WBRobust signal in WB in K-562 and Hep G2 whole cell lysates.
Date published: 2017-01-15
Rated 5 out of 5 by from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic and nuclear staining in formalin fixed, paraffin-embedded human hippocampus tissue. -SCBT QC
Date published: 2015-01-27
Rated 5 out of 5 by from Nice Western Blot data of EBP1 expression in KNice Western Blot data of EBP1 expression in K-562, Jurkat, T-47D, HeLa and Hep G2 whole cell lysates. -SCBT QC
Date published: 2014-06-27
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EBP1 抗体 (C-11) is rated 5.0 out of 5 by 4.
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