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E-Selectin/CD62E/SELE Antibody (CTB202) - Western Blotting - Image 5269
E-Selectin 抗体 (CTB202): sc-5262. 对 HeLa 全细胞裂解液中 E-Selectin 的表达进行 Western 印迹分析.
E-Selectin 抗体 (CTB202): sc-5262. 对 HeLa 全细胞裂解液中 E-Selectin 的表达进行 Western 印迹分析.

E-Selectin/CD62E/SELE 抗体 (CTB202): sc-5262

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寫評論提問
说明书
  • E-Selectin/CD62E/SELE 抗体 CTB202 是小鼠单克隆 IgG2a, 在10篇文献中引用，提供 200 µg/ml
  • 针对全长E-Selectin，human起源
  • 推荐用于 human 来源的E-Selectin WB, IP 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 E-Selectin/CD62E/SELE (D-7): sc-137054，可查看有标记的 E-Selectin/CD62E/SELE 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前，我们还没有完成E-Selectin/CD62E/SELE 抗体 (CTB202)的首选二抗检测试剂的鉴定。这项工作正在进行中。
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関連項目

额外Selectin抗体，包括E-Selectin, L-Selectin和P-Selectin

选择素，也称为CD62抗原，是一类参与介导细胞与白细胞相互作用的糖结合蛋白家族。L-选择素（也称为LECAM-1或CD62L）在大多数B细胞和幼稚T细胞以及大多数单核细胞、中性粒细胞和嗜酸性粒细胞上表达。L-选择素与活化内皮细胞表达的特定碳水化合物相互作用。P-选择素（也称为GMP-140或CD62P）在活化的血小板和内皮细胞上表达，而E-选择素（也称为ELMA-1或CD62E）在内皮细胞上表达，它们表现出重叠的配体特异性。E-选择素由细胞因子刺激的内皮细胞表达，并被认为通过介导细胞与血管内膜的粘附而在炎症部位负责血液白细胞的积累。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

E-Selectin/CD62E/SELE 抗体 (CTB202) 参考文献:

  1. 人类白细胞上的E-选择素受体。  |  Nimrichter, L., et al. 2008. Blood. 112: 3744-52. PMID: 18579791
  2. E-选择素靶向共聚物可减少动脉粥样硬化病变、不良心脏重塑和功能障碍。  |  Tsoref, O., et al. 2018. J Control Release. 288: 136-147. PMID: 30165141
  3. E-选择素与其配体的功能结合通过其凝集素结构域以外的结构特征得到增强。  |  Aleisa, FA., et al. 2020. J Biol Chem. 295: 3719-3733. PMID: 31949047
  4. 与E-选择素的粘附通过AKT和mTOR激活巨噬细胞。  |  Davies, JM., et al. 2021. Immunol Cell Biol. 99: 622-639. PMID: 33565143
  5. 在福尔马林固定、石蜡包埋的切片上检测血管E-选择素表达，E-选择素单克隆抗体与溃疡性结肠炎活动相关。  |  Murahashi, M., et al. 2022. J Histochem Cytochem. 70: 299-310. PMID: 35253509
  6. 一种基于纳米酶的竞争性电化学免疫传感器，用于测定E-选择素。  |  Zhao, L., et al. 2022. Mikrochim Acta. 189: 406. PMID: 36198886
  7. E-选择素的血浆水平与镰状细胞病的视网膜病变有关。  |  Agouti, I., et al. 2023. Eur J Haematol. 110: 271-279. PMID: 36409296
  8. 新型pH响应E-选择素靶向天然多糖杂化胶束用于糖尿病肾病。  |  Guo, C., et al. 2023. Nanomedicine. 52: 102696. PMID: 37394108
  9. E-选择素靶向金纳米壳可抑制乳腺癌细胞与肺内皮细胞的结合。  |  Fereshteh, Z., et al. 2023. ACS Appl Nano Mater. 6: 1315-1324. PMID: 37789828
  10. 氧化应激、微粒和E-选择素与HIV抑制无关。  |  Havlickova, K., et al. 2024. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub.. PMID: 38390755

订购信息

产品名称产品编号规格价格数量收藏夹

E-Selectin/CD62E/SELE 抗体 (CTB202)

sc-5262
200 µg/ml
CNY2422.00

E-Selectin/CD62E/SELE 抗体 (CTB202) FITC

sc-5262 FITC
200 µg/ml
CNY2527.00

E-Selectin/CD62E/SELE 抗体 (CTB202) PE

sc-5262 PE
200 µg/ml
CNY2625.00

Can E-Selectin (CTB202): sc-5262 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Trav11
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, E-Selectin (CTB202): sc-5262 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by HC from Produced publishable quality flow cytometryProduced publishable quality flow cytometry data in HUVEC. -SCBT Publication Review
Date published: 2015-05-18
Rated 5 out of 5 by HF from Good WB publishable data gathered with HUVECGood WB publishable data gathered with HUVEC. -SCBT Publication Review
Date published: 2015-04-23
Rated 5 out of 5 by SS from Publishable IF data with pooled human umbilicalPublishable IF data with pooled human umbilical vein endothelial cells. -SCBT Publication Review
Date published: 2015-03-23
Rated 5 out of 5 by NZ from Great WB signal achieved in HeLa whole cell lysateGreat WB signal achieved in HeLa whole cell lysate. -SCBT QC
Date published: 2015-03-22
Rated 5 out of 5 by LF from Publishable intracellular FCM analysis of THPPublishable intracellular FCM analysis of THP-1 cells and HeLa cells. -SCBT Publication Review
Date published: 2015-03-17
Rated 5 out of 5 by LM from Great WB data obtained using human recombinant EGreat WB data obtained using human recombinant E-Selectin/Fc Chimera homodimer under non-reducing conditions. -SCBT QC
Date published: 2015-02-12
Rated 4 out of 5 by NZ from Produced great FCM data for human peripheralProduced great FCM data for human peripheral blood leukocytes. -SCBT QC
Date published: 2013-04-03
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E-Selectin/CD62E/SELE 抗体 (CTB202) is rated 4.9 out of 5 by 7.
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