Date published: 2025-9-8

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DSC2/3 抗体 (3G130): sc-70994

4.0(2)
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说明书
  • DSC2/3抗体(3G130)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 针对DSC2的胞外结构域,源自human
  • 推荐用于 mouse, rat 和 human 来源的DSC2 and DSC3 WB, IP 和 IF检测
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是DSC2/3 Antibody (3G130) for WB applications. 的首选辅助检测试剂,这些试剂现与DSC2/3 Antibody (3G130) 打包提供(请参阅下面的订购信息)。

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桥粒芯糖蛋白是一类I型膜蛋白,对细胞粘附至关重要,并在桥粒(一种粘附性细胞连接)中大量表达。桥粒芯糖蛋白属于钙粘蛋白家族,包括Dsg1、Dsg2、Dsg3和Dsg4。桥粒钙粘蛋白桥粒芯糖蛋白 DSC1和DSC3也是I型膜蛋白,它们可能通过介导表达不同异构体的细胞之间的差异性粘附,从而有助于表皮细胞的定位。通过选择性剪接,DSC1和DSC3产生了A和B两种异构体,它们在C端有所不同。DSC2在溶液中表现出同型相互作用,并与Dsg2形成异型相互作用。DSC2和DSC1在基底上层皮肤中的含量较高。Dsc2蛋白主要定位于皮层和髓质之间的特化粘附连接处。DSC3在所有活表皮层以及腺管、基底基质细胞和毛囊外根鞘中都有表达。DSC3还存在于其他分层上皮(如宫颈、舌头和食道)的基底和基底上层细胞的桥粒中,也存在于膀胱尿路上皮基底层细胞和气管复合上皮的细胞中,但DSC1并不存在于这些位置。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

DSC2/3 抗体 (3G130)

sc-70994
200 µg/ml
RMB2377.00

DSC2/3 (3G130): m-IgG Fc BP-HRP 套装

sc-539326
200 µg Ab; 10 µg BP
RMB2662.00

DSC2/3 (3G130): m-IgG1 BP-HRP 套装

sc-541411
200 µg Ab; 20 µg BP
RMB2662.00

Are there any issues with using sc-70994: DSC2/3 (3G130) mouse monoclonal primary antibody on mouse samples?

Asked by: AbPolly
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-70994 conjugates.
Answered by: Technical Support
Date published: 2017-03-07
  • y_2025, m_9, d_6, h_5CST
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Rated 4 out of 5 by from Good specificity in WB in mouse transfectedGood specificity in WB in mouse transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-05-03
Rated 4 out of 5 by from Positive signal in WB in HeLa whole cell lysatePositive signal in WB in HeLa whole cell lysate. -SCBT QC
Date published: 2013-08-13
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DSC2/3 抗体 (3G130) is rated 4.0 out of 5 by 2.
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