Date published: 2025-9-8

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DNASE1L1 抗体 (KK-M3): sc-134320

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说明书
  • DNASE1L1 抗体 KK-M3 是小鼠单克隆 IgG1 (kappa轻链),DNASE1L1抗体,规格为100 µg/ml
  • 针对human重组DNASE1L1蛋白的抗原性氨基酸
  • 推荐用于 human 来源的DNASE1L1 WB, IP 和 ELISA检测
  • 关于如何获取DNASE1L1 (KK-M3): sc-134320免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前,我们还没有完成DNASE1L1 抗体 (KK-M3)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    DNASE1L1抗体(KK-M3)是一种IgG1 κ型小鼠单克隆DNASE1L1抗体(也被称为DNASE1L1抗体),该抗体能够通过蛋白质印迹(WB)、免疫沉淀(IP)和酶联免疫吸附测定(ELISA)等方法检测人源DNASE1L1蛋白。DNASE1L1抗体(KK-M3)可作为非偶联的抗DNASE1L1抗体使用。DNASE1L1(脱氧核糖核酸酶I类似物1),也被称为XIB、DNL1L或DNASEX,是一种包含302个氨基酸的蛋白质,它定位于内质网,属于脱氧核糖核酸酶家族。该蛋白在心脏和骨骼肌中高表达,在全身各种组织中低表达。DNASE1L1存在多种可变剪接异构体,其作用方式被认为与DNase I相似,可能通过催化裂解事件介导核小体间DNA的降解。编码DNASE1L1的基因位于人类X染色体上,该染色体含有近1.53亿个碱基对和超过1000个基因。X染色体与Y染色体一起决定性别。存在许多与性染色体数量和组合异常相关的疾病,其中一些包括特纳综合征、色盲、血友病和杜氏肌营养不良症。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    DNASE1L1 抗体 (KK-M3) 参考文献:

    1. 新型内切酶(Xib)的分子特征及可能与溶酶体糖原贮积症的关系。  |  Malferrari, G., et al. 1999. Exp Mol Pathol. 66: 123-30. PMID: 10409440
    2. 酸性麦芽糖酶缺乏症中的X连锁DNase I样基因DNASE1L1的缺失多态性。  |  Malferrari, G., et al. 2001. Exp Mol Pathol. 70: 173-4. PMID: 11263960
    3. 哺乳动物 DNase X 蛋白的物理和生物化学特性:猪和牛 DNase X mRNA 的非 AUG 翻译引发剂。  |  Shiokawa, D., et al. 2005. Biochem J. 392: 511-7. PMID: 16107205
    4. 人类 X 染色体上一种 DNase 的分离, 差异剪接和蛋白表达。  |  Coy, JF., et al. 1996. Cell Death Differ. 3: 199-206. PMID: 17180083
    5. 人类 Xq28 中的肌肉特异性 DNase I 样基因。  |  Parrish, JE., et al. 1995. Hum Mol Genet. 4: 1557-64. PMID: 8541839
    6. 在人类 Xq28 区域克隆出编码类似 DNase I 内切酶的基因。  |  Pergolizzi, R., et al. 1996. Gene. 168: 267-70. PMID: 8654957
    7. 两个与脱氧核糖核酸酶 I 相似的新型人类基因的鉴定, 定域和表达。  |  Rodriguez, AM., et al. 1997. Genomics. 42: 507-13. PMID: 9205125

    订购信息

    产品名称产品编号规格价格数量收藏夹

    DNASE1L1 抗体 (KK-M3)

    sc-134320
    100 µg/ml
    RMB2504.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with DNASE1L1 (KK-M3): sc-134320 antibody?

    Asked by: TinTin
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-27
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    Rated 5 out of 5 by from Good for Western BlotAntibody detects human DNASE1L1 in 293T, A-673, and human DNASE1L1 transfected cell lysate by Western blot. -SCBT QC
    Date published: 2023-09-14
    Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB. -SCBT QC
    Date published: 2015-06-23
    Rated 4 out of 5 by from Clean band in western blot analysis of DNASE1L1Clean band in western blot analysis of DNASE1L1 expression in A-673 and 293T whole cell lysates. -SCBT QC
    Date published: 2014-01-16
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    DNASE1L1 抗体 (KK-M3) is rated 4.0 out of 5 by 3.
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