二苯基-1-芘基膦(DPPP)是一种探针,可与氢过氧化物发生化学反应,生成荧光分子二苯基-1-芘基氧化膦(DPPP-O)1 。DPPP 还被用作检测低密度脂蛋白和细胞氧化的荧光探针4。
Diphenyl-1-pyrenylphosphine (CAS 110231-30-6) 参考文献
1 Okimoto, Y., Watanabe, A., Niki, E., et al. A novel fluorescent probe diphenyl-1-pyrenylphosphine to follow lipid peroxidation in cell membranes. FEBS Lett 474 137-140 (2000). 2 Alasaka, K., Ijichi, S., Watanabe, K., et al. High performance liquid chromatography and post column derivatization with DPPP for fluorometric determination of triglycerol hydropeoxides. J Chromatogr 596 197-202 (1992). 3 Akassaka, K., Ijichi, S., Ohrui, H., et al. Simultaneous determination of hydroperoxides of phosphotidylcholine, cholesterol esters and triglycerols by column-switiching HPLC witha postcolumn detection system. J Chromatogr 622 153-159 (1993). 4 Okimoto, Y., Warabi, E., Wada, Y., et al. A novel method of following oxidation of low-density lipoprotein using a sensitive fluorescent probe, diphenyl-1-pyrenylphosphine. Free Radic Biol Med 35(6) 576-585 (2003).