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Dhh 抗体 (A-10): sc-133243

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说明书
  • Dhh抗体(A-10)是小鼠单克隆IgG2a (kappa轻链),规格为200 µg/ml
  • 免疫human物种的Dhh的氨基酸227-311
  • 推荐用于 mouse, rat 和 human 来源的Dhh WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP和 2a BP-HRP">m-IgG2a BP-HRP是Dhh Antibody (A-10) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Dhh Antibody (A-10) 打包提供(请参阅下面的订购信息)。
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    果蝇的节段极性基因hedgehog(hh)编码一种前体蛋白,这种前体蛋白会经历自切割过程,生成一个氨基端肽和一个羧基端肽。这两种肽都会被分泌出来,并在胚胎和成虫盘模式中发挥作用。已经鉴定出几种果蝇hh的脊椎动物同源物,包括Sonic hedgehog(Shh)(也称为Vhh-1)、Desert hedgehog(Dhh)和Indian hedgehog(Ihh)。它们都含有氨基端信号肽,显然作为分泌蛋白参与介导各种细胞间的相互作用。Shh与果蝇的hh相似,其处理过程会产生一个保留在细胞表面或附近的氨基端分泌肽,以及一个羧基端糖基化后更易扩散的肽。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Dhh 抗体 (A-10) 参考文献:

    1. DHH超家族蛋白在原核生物和真核生物核酸代谢和应激耐受中的作用。  |  Srivastav, R., et al. 2019. Int J Biol Macromol. 127: 66-75. PMID: 30578903
    2. GATA4/6在大鼠肾上腺皮质自体移植中调节DHH转录。  |  Yoshida, T., et al. 2020. Sci Rep. 10: 446. PMID: 31949236
    3. 全长 Dhh 和 N 端 Shh 可作为竞争性拮抗剂调节血管生成和血管通透性。  |  Hollier, PL., et al. 2021. Cardiovasc Res. 117: 2489-2501. PMID: 33063110
    4. Dhh信号通路调控曲细精管样结构的重建  |  Min, M., et al. 2022. Reprod Biol. 22: 100684. PMID: 35987158
    5. Hedgehog信号在性腺发育和功能中的作用。  |  Dilower, I., et al. 2023. Cells. 12: PMID: 36766700
    6. Schwann细胞中的盐皮质激素受体敲除改变了髓鞘厚度。  |  González-Mayoral, A., et al. 2023. J Endocrinol. 258: PMID: 37195271
    7. Nav1.7在小鼠痛觉感受器动作电位中至关重要,其作用方式与内源性阿片类药物无关。  |  Deng, L., et al. 2023. Neuron. 111: 2642-2659.e13. PMID: 37352856
    8. 在骨骼肌再生过程中,Hedgehog信号通过其配体DHH作为细胞命运决定因子发挥作用。  |  Norris, AM., et al. 2023. Nat Commun. 14: 3766. PMID: 37355632
    9. PRUNE1综合征的神经影像学:文献小评。  |  Scorrano, G., et al. 2023. Front Neurol. 14: 1301147. PMID: 38178891
    10. 在患有抗阿柏西普的新血管性年龄相关性黄斑变性的患者中,改用法西单抗治疗的短期结果。  |  Schneider, M., et al. 2024. Graefes Arch Clin Exp Ophthalmol. 262: 2153-2162. PMID: 38416237

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Dhh 抗体 (A-10)

    sc-133243
    200 µg/ml
    CNY2422.00

    Dhh (A-10): m-IgG Fc BP-HRP 套装

    sc-539874
    200 µg Ab; 10 µg BP
    CNY2715.00

    Dhh (A-10): m-IgG2a BP-HRP 套装

    sc-546805
    200 µg Ab; 10 µg BP
    CNY2715.00

    What is the recommended starting dilution for Western blot for Dhh (A-10): sc-133243 monoclonal antibody?

    Asked by: DefinitelyNotMatt
    Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-133243.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by QZ from Nice Western blot data of Dhh expression in nonNice Western blot data of Dhh expression in non-transfected and human Dhh transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-02-12
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    Dhh 抗体 (A-10) is rated 5.0 out of 5 by 1.
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