Deoxycholic acid sodium salt CAS: 302-95-4
MF: C24H39O4•Na
MW: 414.55
An ionic detergent for the solubilization of membrane-bound proteins.

Deoxycholic acid sodium salt (CAS 302-95-4)

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Alternate Names: Sodium deoxycholate
Application: Deoxycholic acid sodium salt is an ionic detergent for the solubilization of membrane-bound proteins
CAS Number: 302-95-4
Molecular Weight: 414.55
Molecular Formula: C24H39O4•Na
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Deoxycholic Acid, Sodium Salt is an ionic detergent for the solubilization of membrane-bound proteins. Deoxycholic Acid, Sodium Salt is reported to induce tyrosine phosphorylation of b-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 μM).


参考文献

1. Pai, Rama., et al., 2004. Deoxycholic acid activates beta-catenin signaling pathway and increases colon cell cancer growth and invasiveness. Molecular biology of the cell. 15(5): 2156-63. PMID: 15004225

Physical State :
Solid
Solubility :
Soluble in water (330 g/l) at 15 °C, DMSO, methanol, and ethanol (very slightly).
Storage :
Store at room temperature
Melting Point :
357-365° C
Optical Activity :
α20/D +55°, c = 1 in ethanol; α20/D +45.1°, c = 0.98 in methanol; α20/D 44°, c = 2 in water
pK Values :
pKa: 6.58, 6.2, 4.76 (Predicted)
仅供科研使用。不可用于诊断或治疗。
WGK Germany :
3
RTECS :
FZ2250000
PubChem CID :
23668196
Merck Index :
14: 2899
MDL Number :
MFCD00064139
EC Number :
206-132-7
Beilstein Registry :
3581950

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