Date published: 2025-9-7

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DEF-3 抗体 (G-6): sc-376222

5.0(2)
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说明书
  • DEF-3抗体(G-6)是小鼠单克隆IgG2a (kappa轻链),规格为200 µg/ml
  • 免疫原氨基酸序列201-500位于human物种的DEF-3的N-terminus附近
  • 推荐用于 mouse, rat 和 human 来源的DEF-3 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP是DEF-3 Antibody (G-6) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与DEF-3 Antibody (G-6) 搭配使用(请参阅下面的订购信息)。

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    関連項目

    DEF-3和LUCA15属于进化上保守的RNA结合蛋白家族,并具有相似的表达模式。DEF-3和LUCA15均在成人心脏和胸腺以及胎儿肾脏中高表达。相反,胎儿胸腺和成人肾脏中DEF-3和LUCA15的表达量很少。在小鼠的造血系统中,当祖细胞分化为粒细胞时,DEF-3的表达下调,但在巨噬细胞发育过程中持续存在。DEF-3和LUCA15都含有两个锌指模体,一个二元核信号和两个RNA结合模体。DEF-3和LUCA15能够特异性结合poly(G) RNA。编码人DEF-3和LUCA15的基因位于3p21.3,这是小细胞肺癌细胞系GLC20中纯合性缺失的区域。肺癌的发生源于显性和隐性癌基因的突变,而染色体3p包含许多这些隐性癌基因。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    DEF-3 抗体 (G-6)

    sc-376222
    200 µg/ml
    RMB2377.00

    DEF-3 (G-6): m-IgG Fc BP-HRP 套装

    sc-540531
    200 µg Ab; 10 µg BP
    RMB2662.00

    What is the recommended starting dilution for Western blot for DEF-3 (G-6): sc-376222 monoclonal antibody?

    Asked by: Randy McDonald
    Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-376222.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western Blot data of DEFProduced positive Western Blot data of DEF-3 expression in Hep G2 nuclear extract and human brain tissue extract . -SCBT QC
    Date published: 2015-04-14
    Rated 5 out of 5 by from Nice Western Blot data of DEFNice Western Blot data of DEF-3 expression in A549 whole cell lysate. -SCBT QC
    Date published: 2014-05-10
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    DEF-3 抗体 (G-6) is rated 5.0 out of 5 by 2.
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