Date published: 2025-9-7

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DDX3 抗体 (C-4): sc-365768

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说明书
  • DDX3 抗体 C-4 是小鼠单克隆 IgG2b κ,DDX3抗体, 在25篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列1-114位于human物种的DDX3x的N-terminus
  • DDX3 抗体 (C-4) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 DDX3X and DDX3Y
  • 抗DDX3抗体(C-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取DDX3 (C-4): sc-365768免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2b BP-HRPm-IgGκ BP-HRP 是 DDX3 抗体 (C-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与DDX3 抗体 (C-4) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

DDX3抗体(C-4)是一种IgG2b κ小鼠单克隆DDX3抗体(也称为DDX3X抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的DDX3蛋白。DDX3抗体(C-4)既可作为非共轭的抗DDX3抗体形式提供,也可作为多种共轭的抗DDX3抗体形式提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®共轭物。DEAD box蛋白以保守的Asp-Glu-Ala-Asp基序为特征,是几种涉及RNA二级结构修饰以及核糖体和剪接体组装的细胞过程中的假定RNA解旋酶。根据其分布模式,该家族的某些成员可能参与胚胎发育、精子发生以及细胞生长和分裂。DDX3(DEAD box多肽3)参与RNA代谢。在人类中发现了两种DDX3同源物;DDX3X由X染色体上的基因编码,而DDX3Y由Y染色体上的基因编码。DDX3Y仅在睾丸中表达,是正常精子发生所必需的。DDX3X普遍表达,主要定位于核斑点,参与RNA剪接、转录、翻译起始、mRNA转运和细胞周期调控。DDX3X还参与HIV-1复制和丙型肝炎病毒感染。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

DDX3 抗体 (C-4) 参考文献:

  1. DEAD-box RNA解旋酶的Ded1/DDX3亚家族。  |  Sharma, D. and Jankowsky, E. 2014. Crit Rev Biochem Mol Biol. 49: 343-60. PMID: 25039764
  2. DDX3 RNA解旋酶在基因调控、肿瘤发生和病毒感染中的多种功能。  |  Ariumi, Y. 2014. Front Genet. 5: 423. PMID: 25538732
  3. DDX3通过表观遗传学调控肝癌中肿瘤抑制性miRNA来抑制干细胞。  |  Li, HK., et al. 2016. Sci Rep. 6: 28637. PMID: 27344963
  4. DDX3在癌症进展中具有双重功能,既是癌基因又是肿瘤抑制基因(综述)。  |  He, Y., et al. 2018. Oncol Rep. 39: 883-892. PMID: 29328432
  5. DDX3通过ALKBH5介导的FOXM1和NANOG的m6A-去甲基化调节OSCC的顺铂耐药性。  |  Shriwas, O., et al. 2020. Apoptosis. 25: 233-246. PMID: 31974865
  6. DDX3上调过氧化氢诱导的Sk-Mel-2人黑色素瘤细胞中的黑色素生成。  |  Eom, S., et al. 2022. Molecules. 27: PMID: 36296601
  7. RNA解旋酶DDX3及其在c-MYC驱动的生殖细胞中心来源的B细胞淋巴瘤中的作用。  |  Lacroix, M., et al. 2023. Front Oncol. 13: 1148936. PMID: 37035206
  8. DDX3通过调节外泌体的分泌和组成来抑制肝癌进展。  |  Su, YY., et al. 2023. Am J Cancer Res. 13: 1744-1765. PMID: 37293175
  9. 通过抑制热解作用,沉默DDX3可减轻白细胞介素-1β诱导的椎间盘退化。  |  Zhong, H., et al. 2024. Inflammation.. PMID: 38735906
  10. DDX3通过翻译控制对女性生育能力至关重要。  |  Tsai, SY., et al. 2024. Cell Death Discov. 10: 472. PMID: 39551844

订购信息

产品名称产品编号规格价格数量收藏夹

DDX3 抗体 (C-4)

sc-365768
200 µg/ml
RMB2377.00

DDX3 (C-4): m-IgG Fc BP-HRP 套装

sc-529459
200 µg Ab; 10 µg BP
RMB2662.00

DDX3 (C-4): m-IgGκ BP-HRP 套装

sc-522357
200 µg Ab, 40 µg BP
RMB2662.00

DDX3 (C-4): m-IgG2b BP-HRP 套装

sc-550113
200 µg Ab; 10 µg BP
RMB2662.00

DDX3 抗体 (C-4) AC

sc-365768 AC
500 µg/ml, 25% agarose
RMB3129.00

DDX3 抗体 (C-4) HRP

sc-365768 HRP
200 µg/ml
RMB2377.00

DDX3 抗体 (C-4) FITC

sc-365768 FITC
200 µg/ml
RMB2482.00

DDX3 抗体 (C-4) PE

sc-365768 PE
200 µg/ml
RMB2580.00

DDX3 抗体 (C-4) Alexa Fluor® 488

sc-365768 AF488
200 µg/ml
RMB2685.00

DDX3 抗体 (C-4) Alexa Fluor® 546

sc-365768 AF546
200 µg/ml
RMB2685.00

DDX3 抗体 (C-4) Alexa Fluor® 594

sc-365768 AF594
200 µg/ml
RMB2685.00

DDX3 抗体 (C-4) Alexa Fluor® 647

sc-365768 AF647
200 µg/ml
RMB2685.00

DDX3 抗体 (C-4) Alexa Fluor® 680

sc-365768 AF680
200 µg/ml
RMB2685.00

DDX3 抗体 (C-4) Alexa Fluor® 790

sc-365768 AF790
200 µg/ml
RMB2685.00

What is the total volume provided of DDX3 (C-4): sc-365768 monoclonal antibody?

Asked by: jenni
Each vial contains 200 µg IgG2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin.
Answered by: Technical Support 15
Date published: 2017-01-25
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Rated 5 out of 5 by from Strong and very clean signal WBI just tried this Ab in its trial size. In WB the signal is very clean and strong at the correct MW, thus I will buy the full size. Lane 1 and 2 are MSTO-211H mesothelioma cell lines plain and engineered by CRISPRi with a control non-targeting guide.
Date published: 2025-05-15
Rated 5 out of 5 by from Excellent antibodyThe C-4 clone is an excellent choice for Western blot yielding specific and consistent results.
Date published: 2017-01-13
Rated 5 out of 5 by from High specificityI bought this several weeks ago, and this antibody fit my demand well, great product!
Date published: 2016-10-27
Rated 5 out of 5 by from Good specificity in WB in NIH/3T3Good specificity in WB in NIH/3T3, A-431, Jurkat and PC-12 nuclear extracts. -SCBT QC
Date published: 2015-06-30
Rated 5 out of 5 by from Produced superb immunofluorescence nucleolarProduced superb immunofluorescence nucleolar and cytoplasmic staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-05-21
Rated 5 out of 5 by from Robust signal in WB in HeLa whole cell lysateRobust signal in WB in HeLa whole cell lysate. -SCBT QC
Date published: 2015-02-22
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DDX3 抗体 (C-4) is rated 5.0 out of 5 by 6.
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