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DcR3 抗体 (G-4): sc-166176

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说明书
  • DcR3抗体(G-4)是小鼠单克隆IgG2b (kappa轻链),规格为200 µg/ml
  • 免疫human物种的DcR3的氨基酸171-300
  • 推荐用于 human 来源的DcR3 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP2b BP-HRP">m-IgG2b BP-HRP是DcR3 Antibody (G-4) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与DcR3 Antibody (G-4) 打包提供(请参阅下面的订购信息)。

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    関連項目

    肿瘤坏死因子(TNF)是一种多效性细胞因子,其功能由两种不同的细胞表面受体介导,这两种受体被命名为TNF-R1和TNF-R2,它们在大多数细胞类型上都有表达。TNF的功能主要通过TNF-R1信号进行介导。这两种受体都属于不断增长的TNF受体超家族,其中包括FAS抗原和CD40。TNF-R1含有一个细胞质基序,称为"死亡结构域",已被发现对于凋亡信号的传导是必需的。死亡结构域也存在于其他几种受体中,包括FAS、DR2(或TRUNDD)、DR3(死亡受体3)、DR4、DR5和DR6。TRUNDD、DR4和DR5是诱导凋亡的细胞因子TRAIL的受体。不含死亡结构域的受体,被指定为诱饵受体1(DcR1)或TRID、DcR2和DcR3,它们与特定配体结合,并可能在细胞对凋亡刺激的抵抗中发挥作用。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    DcR3 抗体 (G-4) 参考文献:

    1. TNFR家族中的诱饵受体DcR3的定量和检测。  |  Chen, J., et al. 2004. J Immunol Methods. 285: 63-70. PMID: 14871535
    2. DcR3的过度表达及其对胶质瘤细胞分化和增殖的意义。  |  Huang, S., et al. 2014. ScientificWorldJournal. 2014: 605236. PMID: 24741354
    3. DcR3在肺癌组织中的表达和临床病理意义:一项涉及365例病例的组织微阵列研究。  |  Zhang, Y., et al. 2016. Onco Targets Ther. 9: 4959-68. PMID: 27570459
    4. 在阿尔茨海默氏病模型中,DcR3可改善淀粉样蛋白和β蛋白引起的缺陷。  |  Liu, YL., et al. 2017. Mol Neurodegener. 12: 30. PMID: 28438208
    5. DcR3与血液学特征相结合,可作为诊断癌症转移的宝贵生物标志物。  |  Li, J., et al. 2017. Oncotarget. 8: 107612-107620. PMID: 29296192
    6. 微生物毒素刺激下血管内皮细胞(HUVEC)中DcR3的上调涉及NF-κB信号。  |  Hou, Y., et al. 2018. BMC Biochem. 19: 13. PMID: 30587127
    7. TGF-β3-Smads-Sp1轴在DcR3介导的肝癌免疫逃逸中的作用。  |  Zhu, HF., et al. 2019. Oncogenesis. 8: 43. PMID: 31409774
    8. DcR3通过DcR3/STAT1/IRF1反馈环促进胰腺癌的增殖和侵袭。  |  Wei, Y., et al. 2019. Am J Cancer Res. 9: 2618-2633. PMID: 31911850
    9. HIF-1α调节DcR3以促进子宫内膜异位症的发展。  |  Guan, J., et al. 2024. Eur J Obstet Gynecol Reprod Biol. 296: 185-193. PMID: 38458034
    10. DcR3抑制痛风性炎症中的NF-κB通路和NLRP3炎症小体激活。  |  Jiang, Y., et al. 2024. Chin Med J (Engl). 137: 2644-2646. PMID: 39294866

    订购信息

    产品名称产品编号规格价格数量收藏夹

    DcR3 抗体 (G-4)

    sc-166176
    200 µg/ml
    RMB2377.00

    DcR3 (G-4): m-IgG Fc BP-HRP 套装

    sc-540036
    200 µg Ab; 10 µg BP
    RMB2662.00

    DcR3 (G-4): m-IgG2b BP-HRP 套装

    sc-549767
    200 µg Ab; 10 µg BP
    RMB2662.00

    What is the recommended starting dilution for Western blot for DcR3 (G-4): sc-166176 monoclonal antibody?

    Asked by: Professor Griffin
    Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-166176.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western blot data of DcR3Produced positive Western blot data of DcR3 expression in non-transfected and human DcR3 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-01-19
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    DcR3 抗体 (G-4) is rated 5.0 out of 5 by 1.
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