Date published: 2025-9-7
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DC-SIGN/DC-SIGNR Antibody (14E3G7) - Western Blotting - Image 34918
DC-SIGN/DC-SIGNR 抗体 (14E3G7): sc-53965. 未转染: sc-117752 (A) 和转染: sc-115461 (B) 293T 全细胞裂解液中 DC-SIGNR 表达的 Western 印迹分析.
DC-SIGN/DC-SIGNR Antibody (14E3G7) - Western Blotting - Image 34918
DC-SIGN/DC-SIGNR 抗体 (14E3G7): sc-53965. 未转染: sc-117752 (A) 和转染: sc-115461 (B) 293T 全细胞裂解液中 DC-SIGNR 表达的 Western 印迹分析.
DC-SIGN/DC-SIGNR Antibody (14E3G7) - Western Blotting - Image 15726
DC-SIGN/DC-SIGNR 抗体 (14E3G7): sc-53965. 人重组 DC-SIGN 融合蛋白 (A) 和 DC-SIGN 在 THP-1 (B) 及 PMA 和 IL-4 处理的 THP-1 (C) 全细胞裂解液中的表达的 Western 印迹分析.
DC-SIGN/DC-SIGNR 抗体 (14E3G7): sc-53965. 未转染: sc-117752 (A) 和转染: sc-115461 (B) 293T 全细胞裂解液中 DC-SIGNR 表达的 Western 印迹分析.

DC-SIGN/DC-SIGNR 抗体 (14E3G7): sc-53965

4.0(2)
寫評論提問

说明书
  • DC-SIGN/DC-SIGNR抗体(14E3G7)是小鼠单克隆IgG2b κ, 在1篇文献中引用，规格为200 µg/ml
  • 与human来源的DC-SIGN反应
  • 推荐用于 human 来源的DC-SIGN and DC-SIGNR WB, IP 和 IF检测
  • 目前，我们还没有完成DC-SIGN/DC-SIGNR 抗体 (14E3G7)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

此外 CD209 抗体包括 CD209b, CD209e, DC-SIGN 和 DC-SIGNR

树突状细胞（DC）是存在于外周黏膜组织并迁移到淋巴组织的抗原呈递免疫系统细胞。DC-SIGN（树突状细胞特异性ICAM-3结合非整合素）是仅由树突状细胞表达的II型膜蛋白。DC-SIGN，也被称为CD209，与ICAM-3结合，通过免疫突触介导树突状细胞和静息T细胞之间的初始相互作用。存在于HIV-1感染初始部位的树突状细胞通过DC-SIGN捕获HIV-1，然后促进树突状细胞迁移到富含T细胞的次级淋巴器官区域，在那里促进这些T细胞的有效HIV-1跨感染。DC-SIGNR（DC-SIGN相关分子），也被称为CD209L和L-SIGN（肝/淋巴结特异性ICAM-3结合非整合素）是一种II型整体膜蛋白，与DC-SIGN有77%的相似性。它在肝窦内皮细胞上表达，并与丙型肝炎病毒的E2糖蛋白结合。

仅限研究使用。不适用于诊断和治疗用途。

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产品名称产品编号规格价格数量收藏夹

DC-SIGN/DC-SIGNR 抗体 (14E3G7)

sc-53965
200 µg/ml
RMB2377.00

Is it also approved for immunohistochemistry?

Asked by: kbrau
Thank you for your question. Anti-DC-SIGN/DC-SIGNR Antibody (14E3G7): sc-53965 is only recommended for detection of DC-SIGN and DC-SIGNR of human origin by WB, IP and IF. Based on our tests with this product we can not recommend it for histochemistry applications.
Answered by: Tech Support Europe
Date published: 2021-12-27

What is the recommended starting dilution for Western blot for sc-53965: DC-SIGN/DC-SIGNR (14E3G7) monoclonal antibody?

Asked by: Professor Griffin
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
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Rated 4 out of 5 by from Positive result in WB using human recombinant DCPositive result in WB using human recombinant DC-SIGN fusion protein, PMA and IL-4 treated THP-1 whole cell lysates. -SCBT QC
Date published: 2015-05-28
Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB. -SCBT QC
Date published: 2013-09-26
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DC-SIGN/DC-SIGNR 抗体 (14E3G7) is rated 4.0 out of 5 by 2.
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