D-Quisqualic acid (CAS 52809-07-1 (L-isomer))

物理状态 :

Solid

溶解度 :

Soluble in 10% Ammonium hydroxide (sparingly soluble in water; 0.5 mg/ml)

保存 :

Store at room temperature

熔点 :

306.71° C (Predicted)

沸点 :

~405.9° C at 760 mmHg (Predicted)

密度 :

~2.0 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.73 (Predicted)

IC50 :

Glutamate receptor ionotropic, AMPA: IC₅₀ = 80 nM (mouse); Glutamate receptor ionotropic, kainate: IC₅₀ = 150 nM (rat); Glutamate receptor ionotropic, AMPA: IC₅₀ = 1.3 µM (rat); : IC₅₀ = 2.9 µM (rat); xCT: IC₅₀ = 5 µM (human)

Ki 数据 :

Metabotropic glutamate receptor 1: K_i= 10 nM (rat); mGluR-5: K_i= 55 nM (human); Glutamate receptor ionotropic kainate 2: K_i= 131.83 nM (rat); Glutamate receptor ionotropic kainate 1: K_i= 169.82 nM (rat); Glutamate receptor ionotropic kainate 3: K_i= 1.38 µM (rat)

pK值 :

pK_a: 2.12 (Predicted), pK_b: 10.05 (Predicted)

PubChem CID :

Merck 索引 :

13,8177

MDL 号码 :

MFCD00069337

SMILES :

C([C@@H](C(=O)O)N)N1C(=O)NC(=O)O1