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Cytokeratin 8 Antibody (M20) - Western Blotting - Image 82618
细胞角蛋白 8 抗体 (M20): sc-52324. Western 印迹分析 MCF7 全细胞裂解液中细胞角蛋白 8 的表达.
细胞角蛋白 8 抗体 (M20): sc-52324. Western 印迹分析 MCF7 全细胞裂解液中细胞角蛋白 8 的表达.

Cytokeratin 8 抗体 (M20): sc-52324

4.3(6)
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说明书
  • Cytokeratin 8 抗体 M20 是小鼠单克隆 IgG1, 在11篇文献中引用，提供 100 µg/ml
  • 针对源自human的乳腺癌细胞系MCF7分离出的角蛋白
  • 推荐用于 mouse, rat 和 human 来源的Cytokeratin 8 WB, IP, IF 和 FCM检测
  • 看 Cytokeratin 8 (C51): sc-8020，可查看有标记的 Cytokeratin 8 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前，我们还没有完成Cytokeratin 8 抗体 (M20)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

此外 Cytokeratin 抗体 包括 Basic Cytokeratin, Cytokeratin 1, Cytokeratin 10, Cytokeratin 12, Cytokeratin 13, Cytokeratin 14, Cytokeratin 15, Cytokeratin 16, Cytokeratin 17和Cytokeratin 18

细胞角蛋白是一组多样化的中间丝蛋白（IFPs），在角质化和非角质化上皮组织中成对表达。细胞角蛋白在维持上皮细胞整体结构完整性的分化、组织特化和功能方面发挥着关键作用。它们已被发现是有用的组织分化标记物，可直接应用于恶性肿瘤的表征。细胞角蛋白8在上皮和上皮源性肿瘤中表达。细胞角蛋白8和18对通常在单纯上皮中表达，但在分层上皮细胞中不表达。研究表明，分层上皮来源的鳞状细胞癌显示细胞角蛋白8和18的表达异常，尽管尚不清楚这些蛋白质是否有助于细胞的恶性表型。口腔鳞状细胞癌中细胞角蛋白8和18的表达是一种提示预后不良的独立预后标志物。细胞角蛋白8的表达与白斑和头颈部癌的恶性程度相关；它在所有非小细胞肺癌中都有表达。细胞角蛋白8已被证明在肿瘤细胞上具有细胞外表位，这可能是有价值的治疗靶点。

仅限研究使用。不适用于诊断和治疗用途。

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产品名称产品编号规格价格数量收藏夹

Cytokeratin 8 抗体 (M20)

sc-52324
100 µg/ml
RMB2377.00

What is the molecular weight of Cytokeratin 8 ?

Asked by: jenniferc
Thank you for your question. Cytokeratin 8 has an expected molecular weight of approximately 40-55 kDa. If you have any questions, please contact our Technical Service Department and we would be happy to assist you.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from This antibody was used in WB (1/500)This antibody was used in WB (1/500), very good results, Published data
Date published: 2016-05-06
Rated 3 out of 5 by from Worked with human transfected lysate by WBWorked with human transfected lysate by WB -SCBT QC
Date published: 2015-03-19
Rated 4 out of 5 by from Positive immunofluorescence staining of methanolPositive immunofluorescence staining of methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-03-07
Rated 5 out of 5 by from Strong blownout band in MCF7 cells on WBStrong blownout band in MCF7 cells on WB. -SCBT QC
Date published: 2015-03-06
Rated 5 out of 5 by from Single clean band in ASingle clean band in A-431 cells. -SCBT QC
Date published: 2015-02-25
Rated 4 out of 5 by from Good cytoplasmic staining with M20 on HeLa samplesGood cytoplasmic staining with M20 on HeLa samples.
Date published: 2015-01-18
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Cytokeratin 8 抗体 (M20) is rated 4.3 out of 5 by 6.
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