Date published: 2025-9-8

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CtBP1 抗体 (G-5): sc-376004

5.0(4)
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说明书
  • CtBP1抗体(G-5)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的CtBP1的C-terminus的氨基酸411-437之间
  • 推荐用于 mouse, rat 和 human 来源的CtBP1 WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: bovine
  • 看 CtBP (E-12): sc-17759,可查看有标记的 CtBP1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgGκ BP-HRP是CtBP1 Antibody (G-5) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现可与CtBP1 Antibody (G-5) 搭配使用(请参阅下面的订购信息)。有关其它 m-IgGκ BP 结合物,请参阅我们完整的小鼠 IgG 结合蛋白列表。

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    関連項目

    CtBP1是一种细胞磷蛋白,它与各种蛋白质结合并作为转录的共抑制因子。CtBP1和相关蛋白CtBP2的特征是腺病毒E1A的C端结合蛋白,它们优先通过5个氨基酸基序PLDLS与E1A结合,以抑制E1A诱导的肿瘤发生和细胞转化。CtBP1从胚胎到成体都有表达,但CtBP2主要在胚胎发育过程中表达。在骨骼和T细胞发育过程中,CtBP1和CtBP2与细胞锌指同源结构域蛋白δEF1的PLDLSL结构域结合,从而增强δEF1诱导的转录沉默。此外,CtBP与CtIP形成复合物,CtIP是一种与CtBP识别完全不同蛋白质基序的蛋白质。CtIP与乳腺癌基因BRCA1中的BRCT重复序列结合,使CtBP能够影响BRCA1的活性。CtIP/CtBP与BRCA1的结合抑制了p21启动子的反式激活,这对于调节DNA损伤后的p21转录至关重要。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    CtBP1 抗体 (G-5)

    sc-376004
    200 µg/ml
    RMB2377.00

    CtBP1 (G-5): m-IgGκ BP-HRP 套装

    sc-522814
    200 µg Ab, 40 µg BP
    RMB2662.00

    CtBP1 (G-5) 中和勝肽

    sc-376004 P
    100 µg/0.5 ml
    RMB511.00

    What application is the blocking peptide sc-376004 P appropriate for?

    Asked by: jerojero
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-25
    • y_2025, m_9, d_7, h_4CST
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    Rated 5 out of 5 by from Clean data obtained in western blot analysisClean data obtained in western blot analysis of CtBP1 expression in Jurkat, SH-SY5Y, Raji, A549 and HeLa whole cell lysates. -SCBT QC
    Date published: 2015-05-03
    Rated 5 out of 5 by from Produced exceptional immunofluorescence nuclearProduced exceptional immunofluorescence nuclear staining in formalin-fixed HepG2 cells. -SCBT QC
    Date published: 2015-04-24
    Rated 5 out of 5 by from Great antibody for western blottingGreat antibody for western blotting - produced clean blot with strong bands in HeLa, NIH/3T3 and KNRK nuclear extracts. -SCBT QC
    Date published: 2015-04-08
    Rated 5 out of 5 by from Works great for mouse CtBP1 transfected lysatesWorks great for mouse CtBP1 transfected lysates. -SCBT QC
    Date published: 2015-03-11
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    CtBP1 抗体 (G-5) is rated 5.0 out of 5 by 4.
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