Cromolyn (CAS 16110-51-3)

溶解度 :

Soluble in water (0.21 mg/ml).

熔点 :

241° C

沸点 :

~752.3° C at 760 mmHg (Predicted)

密度 :

~1.6 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.68 (Predicted)

IC50 :

the release of histamine in the rat peritoneal fluids by 50%: IC₅₀ = 0.74 µM (rat); release of histamine in rat passive peritoneal anaphylaxis: IC₅₀ = 0.74 µM (rat); antigen-induced release of histamine (AIR) by 50% from rat peritoneal mast cells (RMC) (in vitro): IC₅₀ = 3 µM (rat); the release of extravasated dye in the rat peritoneal fluids by 50%: IC₅₀ = 5.8 µM (rat); release of extravasation in rat passive peritoneal anaphylaxis: IC₅₀ = 5.8 µM (rat)

Ki 数据 :

GPR35: K_i= 2.34 µM (human)

pK值 :

pK_a: 1.10

PubChem CID :

MDL 号码 :

MFCD00864784

EC号码 :

240-279-8

SMILES :

C1=CC2=C(C(=C1)OCC(COC3=CC=CC4=C3C(=O)C=C(O4)C(=O)O)O)C(=O)C=C(O2)C(=O)O