Date published: 2025-9-8

021-6093-6350

SCBT Portrait Logo
Seach Input

Cox-1 抗体 (6D317): sc-70877

4.3(4)
寫評論提問

说明书
  • Cox-1抗体(6D317)是小鼠单克隆IgG2b κ, 在1篇文献中引用,规格为200 µg/ml
  • 与Cox-1反应,从ovine精囊中纯化
  • 推荐用于 mouse, rat, human 和 ovine 来源的Cyclooxygenase-1 WB, IP, IF, IHC(P) 和 FCM检测; 可能与 human recombinant, human platelet, rat and mouse Cox-1, and slightly (5%) with ovine Cox-2产生交联反应; 不会与 human or mouse Cox-2产生交联反应
  • 看 Cox-1 (11): sc-19998,可查看有标记的 Cox-1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG2b BP-HRPm-IgGκ BP-HRP 是 Cox-1 抗体 (6D317) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Cox-1 抗体 (6D317) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

Cox-1抗体(6D317)是一种小鼠单克隆IgG2b抗体,用于检测环氧化酶-1(Cox-1),也称为前列腺素-内过氧化物酶合酶1(PTGS1)。Cox-1是一种二聚酶,主要位于细胞的内质网和核膜中,在那里Cox-1催化花生四烯酸转化为前列腺素H2,这是合成各种前列腺素的重要前体。Cox-1的结构特征,包括Cox-1的血红素基团和结合位点,对于酶的活性和与非甾体抗炎药(NSAIDs)的相互作用至关重要,因此了解Cox-1的结构对于药物开发和治疗研究至关重要。Cox-1在大多数组织中都有表达,它具有重要的"管家"功能,例如维持胃粘膜完整性、调节血小板聚集和控制肾血流。Cox-1 (6D317) 单克隆抗体针对从绵羊精囊中纯化的 Cox-1 产生,具有广泛的物种反应性,可有效识别小鼠、大鼠、人类和绵羊来源的 Cox-1,可用于包括蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、石蜡包埋切片免疫组织化学(IHCP)和流式细胞术(FCM)在内的多种应用。抗Cox-1抗体(6D317)表现出极低的交叉反应性,对绵羊Cox-2仅有轻微(5%)反应性,且与人或小鼠Cox-2无交叉反应性。通过靶向Cox-1,研究人员可以研究Cox-1在正常生理过程和前列腺素合成中断的病理条件下的作用。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Cox-1 抗体 (6D317)

sc-70877
200 µg/ml
RMB2377.00

Cox-1 (6D317): m-IgGκ BP-HRP 套装

sc-534402
200 µg Ab; 40 µg BP
RMB2662.00

Cox-1 (6D317): m-IgG2b BP-HRP 套装

sc-549251
200 µg Ab; 10 µg BP
RMB2662.00

Does Cox-1 antibody work with C-elegans mitochondria protein?

Asked by: peng27
Thank you for your question. sc-7087 Cox-1 has not been tested for C-elegans. We recommend the antibody for mouse, rat, human and ovine.
Answered by: BlakeJ
Date published: 2024-10-17

Can Cox-1 (6D317): sc-70877 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: Germaine
Thank you for your question. Yes, Cox-1 (6D317): sc-70877 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-02-27
  • y_2025, m_9, d_7, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_70877, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 120ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from Works well for WB with NIH/3T3 whole cell lysateWorks well for WB with NIH/3T3 whole cell lysate.. -SCBT QC
Date published: 2015-03-15
Rated 4 out of 5 by from Good specificity and signal strength withGood specificity and signal strength with some background bands -SCBT QC
Date published: 2015-02-22
Rated 5 out of 5 by from Strong band in WB when used on human CoxStrong band in WB when used on human Cox-1 transfected 293T and U-937 whole cell lysates. -SCBT QC
Date published: 2015-02-09
Rated 4 out of 5 by from Performs well in WesternPerforms well in Western, good signal with rat aortic smooth muscle cells. -SCBT Publication Review
Date published: 2013-07-02
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_70877, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 18ms
  • REVIEWS, PRODUCT
Cox-1 抗体 (6D317) is rated 4.3 out of 5 by 4.
  • y_2025, m_9, d_7, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_70877, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 108ms
  • REVIEWS, PRODUCT