Date published: 2025-10-23

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Contactin 1 抗体 (41): sc-136133

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说明书
  • Contactin 1 抗体 41 是小鼠单克隆 IgG1Contactin 1抗体, 在2篇文献中引用,规格为200 µg/ml
  • 免疫human物种的Contactin 1的氨基酸77-238
  • 推荐用于 mouse, rat 和 human 来源的Contactin 1 WB, IP 和 IF检测
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是Contactin 1 Antibody (41) for WB applications. 的首选辅助检测试剂,这些试剂现与Contactin 1 Antibody (41) 打包提供(请参阅下面的订购信息)。

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関連項目

Contactin 1抗体(41)是一种IgG1小鼠单克隆Contactin 1抗体(也称为Contactin 1抗体),可通过WB、IP和IF检测小鼠、大鼠和人源的Contactin 1蛋白。Contactin 1抗体(41)为非偶联形式的抗Contactin 1抗体。突触效能的变化可以介导学习和记忆形成过程中的关键过程。越来越多的证据表明,细胞粘附分子与配对脉冲易化(PPF)、长时程增强(LTP)和长时程抑制(LTD)等活动依赖的突触修饰有关。在这些过程中涉及的细胞粘附分子有接触蛋白。接触蛋白是免疫球蛋白超家族的成员,在突触可塑性、PPF和LTD中发挥选择性作用,并可能与其他突触靶向分子(包括paranodin和phosphacan)一起调节细胞间的相互作用,从而促进突触可塑性。此外,接触蛋白是控制神经元中Na+通道的表达和分布、旁结连接以及最终有髓神经的生理机能的必要组成部分。人类Contactin 1基因编码一个由1018个氨基酸组成的蛋白质。人类Contactin 3基因编码一个由646个氨基酸组成的浆细胞瘤相关神经元糖蛋白。人类Contactin 5基因编码一个由1100个氨基酸组成的神经粘附分子。人类Contactin 6基因编码一个由1028个氨基酸组成的神经粘附分子。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Contactin 1 抗体 (41) 参考文献:

  1. 接触素协调髓鞘周围神经旁节的隔膜样连接组装。  |  Boyle, ME., et al. 2001. Neuron. 30: 385-97. PMID: 11395001
  2. 接触素与 Na+ 通道结合并增加其功能表达。  |  Kazarinova-Noyes, K., et al. 2001. J Neurosci. 21: 7517-25. PMID: 11567041
  3. 接触素支持与海马长期抑制相关的突触可塑性,但不支持延时。  |  Murai, KK., et al. 2002. Curr Biol. 12: 181-90. PMID: 11839269
  4. 接触素是一种 130 kD 糖蛋白,集中在神经元间接触区域,它的序列定义了神经系统中免疫球蛋白超基因家族的一个新成员。  |  Ranscht, B. 1988. J Cell Biol. 107: 1561-73. PMID: 3049624
  5. 神经细胞粘附分子在活动依赖性发育和突触可塑性中的作用  |  Fields, RD. and Itoh, K. 1996. Trends Neurosci. 19: 473-80. PMID: 8931273

订购信息

产品名称产品编号规格价格数量收藏夹

Contactin 1 抗体 (41)

sc-136133
200 µg/ml
RMB2377.00

Contactin 1 (41): m-IgG Fc BP-HRP 套装

sc-527104
200 µg Ab; 10 µg BP
RMB2662.00

Contactin 1 (41): m-IgG1 BP-HRP 套装

sc-532477
200 µg Ab; 20 µg BP
RMB2662.00

Could you please let me know the actual volume of liquid contained in the commercial vial of this product?I am specifically referring to the total liquid volume, not the concentration.

Asked by: abpr
Thank you for your question, The actual volume is 1ml. If you have any other question, please contact our Technical Service Department. Our Asian Technical Service team is available at (+86) 021-60936350 or [email protected] or by live chat on our website.
Answered by: Sen Li
Date published: 2025-09-09

I am using Contactin 1 (41): sc-136133 for immunofluorescence, what dilution of this antibody should I use?

Asked by: Dr Ninau Qelp
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 2 out of 5 by from Not for immunostaining.I used this antibody for immunostainig of cultured neurons. I saw some signals but that was not I expected from the results using other antibodies.
Date published: 2022-12-22
Rated 1 out of 5 by from Did not workI tested this antibody on mouse brain lysate. But I did not detect any protein band in WB. (1:200 dilution).
Date published: 2018-07-09
Rated 4 out of 5 by from Produced clear immunofluorescence cytoplasmicProduced clear immunofluorescence cytoplasmic staining in human fibroblast cells. -SCBT QC
Date published: 2015-04-18
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Contactin 1 抗体 (41) is rated 2.8 out of 5 by 4.
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