Date published: 2025-9-6

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COL4A3 抗体 (1042): sc-52317

4.5(4)
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说明书
  • COL4A3 抗体 1042 是小鼠单克隆 IgG2b, 在9篇文献中引用,提供 500 µl ascites
  • 与human来源的分离胎盘
  • 推荐用于 human 来源的Collagen α3 Type IV WB, IF 和 IHC(P)检测
  • 目前,我们还没有完成COL4A3 抗体 (1042)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

COL4A3抗体(1042)是一种小鼠单克隆IgG2b抗体,可通过蛋白质印迹(WB)、免疫荧光(IF)和石蜡包埋切片免疫组织化学(IHCP)检测人类来源的IV型胶原蛋白α3(COL4A3)。COL4A3 (1042) 抗体有非结合型可供选择,可满足各种实验需求。COL4A3是基底膜的重要组成部分,是组织和器官的支撑结构。COL4A3的正常功能对于维持细胞外基质的完整性和稳定性至关重要,影响细胞粘附、迁移和分化等过程。COL4A3的异常,包括COL4A3基因突变,可导致一系列疾病,包括以肾功能不全、听力损失和眼部异常为特征的阿尔波特综合征。COL4A3独特的三螺旋结构使其能够形成网络,为组织提供机械支持和过滤特性,这凸显了COL4A3在健康和疾病中的重要性。抗COL4A3抗体(1042)使研究人员能够深入了解COL4A3在各种生物过程中的作用以及在病理条件下的影响。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

COL4A3 抗体 (1042) 参考文献:

  1. 被撤回的文章  |  ..
  2. 胶原蛋白和骨骼强度  |  Boskey, AL., et al. 1999. J Bone Miner Res. 14: 330-5. PMID: 10027897
  3. 评论文章:血小板与胶原蛋白的相互作用:膜受体和细胞内信号途径。  |  Alberio, L. and Dale, GL. 1999. Eur J Clin Invest. 29: 1066-76. PMID: 10583456
  4. 与 IV 型胶原蛋白有关的疾病。  |  Pescucci, C., et al. 2003. J Nephrol. 16: 314-6. PMID: 12768082
  5. 发现作为新型整合素配体和血管生成内源性抑制剂的 IV 型胶原非胶原结构域。  |  Kalluri, R. 2002. Cold Spring Harb Symp Quant Biol. 67: 255-66. PMID: 12858548
  6. CCAAT置换蛋白(CDP/cut)识别乳铁蛋白基因启动子中的沉默子元件。  |  Alves, APVD., et al. 2021. J Perinat Med. 49: 553-558. PMID: 33550735
  7. 在人群测序数据库中预测的致病性COL4A3-COL4A5变异的流行率估计及其对阿尔波特综合征的影响。  |  Gibson, J., et al. 2021. J Am Soc Nephrol. 32: 2273-2290. PMID: 34400539
  8. COL4A3/COL4A4杂合突变:冰山一角?  |  Mastrangelo, A., et al. 2022. Nephrol Dial Transplant. 37: 2398-2407. PMID: 35090027
  9. COL4A3至COL4A5未分类变异体的异常mRNA拼接效应。  |  Zhang, Y., et al. 2023. Kidney Int Rep. 8: 1399-1406. PMID: 37441478
  10. 细胞粘附到胶原基质上。  |  McCarthy, JB., et al. 1996. Biopolymers. 40: 371-81. PMID: 8765608
  11. 无脊椎动物的多功能胶原。  |  Engel, J. 1997. Science. 277: 1785-6. PMID: 9324767
  12. 软骨胶原:综述其结构, 组织以及在动物实验性关节炎和人类风湿病发病机制中的作用。  |  Cremer, MA., et al. 1998. J Mol Med (Berl). 76: 275-88. PMID: 9535561

订购信息

产品名称产品编号规格价格数量收藏夹

COL4A3 抗体 (1042)

sc-52317
500 µl ascites
$316.00

What is the concentration of COL4A (1042): sc-52317 monoclonal antibody?

Asked by: cjMara
Unfortunately, we do not characterize the concentration of antibody when provided as an ascites. Antibodies are provided in ascites fluid with 0.1% sodium azide.
Answered by: Technical Support 7
Date published: 2017-01-24
  • y_2025, m_8, d_28, h_5CST
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Rated 5 out of 5 by from It is recommended to useBest of the COL4A antibodies, strong western blot and IHC
Date published: 2017-05-17
Rated 5 out of 5 by from Very well pulbished antibodyCOL4A Antibody (1042) was cited in multiple publications for WB, ICC, iF and IHC!
Date published: 2017-01-21
Rated 4 out of 5 by from The specificity of this antibody is very goodThe specificity of this antibody is very good.
Date published: 2015-10-28
Rated 4 out of 5 by from Good publication data with human DM and porcineGood publication data with human DM and porcine DE cell. -SCBT QC
Date published: 2015-02-11
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COL4A3 抗体 (1042) is rated 4.5 out of 5 by 4.
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