Ciprofibrate 的分子结构, CAS编号: 52214-84-3
Ciprofibrate (CAS 52214-84-3)
备用名:
2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
应用:
Ciprofibrate 是 PPARα 的降血脂激动剂
CAS号码:
52214-84-3
纯度:
≥98%
分子量:
289.2
分子式:
C13H14Cl2O3
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Ciprofibrate (CAS 52214-84-3) 参考文献
Comparison of the effects of various peroxisome proliferators on peroxisomal enzyme activities, DNA synthesis, and apoptosis in rat and human hepatocyte cultures: V. Goll, et al.; Toxicol. Appl. Pharmacol. 160, 21 (1999) Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate: P. Passilly, et al.; Biochem. Pharmacol. 58, 1001 (1999) Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate: M.C. Clemencet, et al.; Cancer Lett. 222, 217 (2005) P450 CYP2C epoxygenase and CYP4A w-hydroxylase mediate ciprofibrate-induced PPARa-dependent peroxisomal proliferation: A. Gatica, et al.; J. Lipid Res. 48, 924 (2007) Lalwani ND, Reddy MK, Qureshi SA et al. Hum Toxicol. 2:27-48 (1983). Clemencet MC, Muzio G, Trombetta A et al. Cancer Lett. 222:217-226 (2005).抑制剂：
ABCD1, Lipid Biosynthesis, Peroxin 11α, UGT1A10, 和 UGT1A3.激活剂：
17β-HSD11, ABCD2, ACOX2, ACSL1, apoA-I, CAR, CYP4A22, DHCR24, FMO5, OAT, Peroxin 3, PLTP, PPAR alpha, Sodium Taurochenodeoxycholate, 和 TYSND1.订购信息
| 产品名称 | 产品编号 | 规格 | 价格 | 数量 | 收藏夹 | |
Ciprofibrate, 25 mg | sc-204689 | 25 mg | RMB643.00 | |||
Ciprofibrate, 100 mg | sc-204689A | 100 mg | RMB1907.00 |