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Centrin-3 抗体 (SS12): sc-100933

5.0(3)
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说明书
  • Centrin-3抗体(SS12)是小鼠单克隆IgG2b κ, 在3篇文献中引用,规格为50 µg/0.5 ml
  • 免疫human物种的重组Centrin-3
  • 推荐用于 mouse, rat 和 human 来源的Centrin-3 WB, IP 和 ELISA检测
  • 目前,我们还没有完成Centrin-3 抗体 (SS12)的首选二抗检测试剂的鉴定。这项工作正在进行中。
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EF手型Ca2+结合蛋白家族由几个成员组成,包括Centrin-1、Centrin-2和Centrin-3。Centrin蛋白是普遍表达的细胞骨架成分,在细胞分化过程中表达增加。有纤毛的组织,如视网膜和睾丸,同时表达Centrin-1和-2,但Centrin-2也在未分化的、无纤毛的视网膜细胞(视网膜母细胞瘤细胞)、肝脏、骨骼肌和心肌中表达。在这些组织中,Centrin与中心体、有丝分裂纺锤极和基体相关联。敲除研究表明,Centrin对中心粒复制、纺锤极形态的组织和有丝分裂的完成都是必需的。Centrin-3在中心体复制中起作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Centrin-3 抗体 (SS12) 参考文献:

  1. 中心蛋白酶 3 在中心体繁殖中的作用  |  Middendorp, S., et al. 2000. J Cell Biol. 148: 405-16. PMID: 10662768
  2. 人类纤毛细胞体外分化过程中中心蛋白同工酶的差异表达和细胞分布。  |  Laoukili, J., et al. 2000. J Cell Sci. 113 (Pt 8): 1355-64. PMID: 10725219
  3. 鼠睾丸中心体蛋白基因家族(中心体基因)的克隆和表达特性。  |  Sun, X., et al. 2002. Sci China C Life Sci. 45: 655-62. PMID: 18762898
  4. 人类胶质瘤不同阶段中心体蛋白的差异表达。  |  Loh, JK., et al. 2010. BMC Cancer. 10: 268. PMID: 20529377
  5. 人类脑肿瘤中中心体相关蛋白的差异表达:hNinein异构体6在细胞分化中可能发挥的作用。  |  Loh, JK., et al. 2012. Biofactors. 38: 470-7. PMID: 23047184
  6. 在四膜虫基体中,两种人类中心体同源物具有相似但不同的功能。  |  Vonderfecht, T., et al. 2012. Mol Biol Cell. 23: 4766-77. PMID: 23087207
  7. Centrin 3是一种中心体Mps1的抑制剂,可对抗中心体2的功能。  |  Sawant, DB., et al. 2015. Mol Biol Cell. 26: 3741-53. PMID: 26354417
  8. FBXL13 引导 CEP192 蛋白水解,调节中心体稳态和细胞迁移。  |  Fung, E., et al. 2018. EMBO Rep. 19: PMID: 29348145
  9. ACTG1和TLR3是酒精相关性肝细胞癌的生物标志物。  |  Gao, B., et al. 2019. Oncol Lett. 17: 1714-1722. PMID: 30675230
  10. 交互组学分析揭示了新型ALMS1-CEP70复合物与中心体簇的关联。  |  Woerz, F., et al. 2024. Mol Cell Proteomics. 23: 100701. PMID: 38122899

订购信息

产品名称产品编号规格价格数量收藏夹

Centrin-3 抗体 (SS12)

sc-100933
50 µg/0.5 ml
$339.00

What is the molecular weight of Centrin-3 ?

Asked by: cjMara
Thank you for your question. Centrin-3 has an expected molecular weight of approximately 20 kDa. If you have any questions, please contact our Technical Service Department and we would be happy to assist you.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by LF from 1:300 dilution used for IF with human U2OS cells1:300 dilution used for IF with human U2OS cells. -SCBT Publication Review
Date published: 2015-03-03
Rated 5 out of 5 by JR from WB: strong bands in RAW 264WB: strong bands in RAW 264.7 whole cell lysate and rat testis tissue extract. -SCBT QC
Date published: 2015-01-08
Rated 5 out of 5 by SF from Clean bands in western blot analysis of CentrinClean bands in western blot analysis of Centrin-3 expression in Jurkat and HeLa whole cell lysates. -SCBT QC
Date published: 2014-07-26
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Centrin-3 抗体 (SS12) is rated 5.0 out of 5 by 3.
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