Date published: 2025-9-7
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CD79B Antibody (SN8) - Western Blotting - Image 356894
CD79B 抗体 (SN8): sc-18902. U-698-M (A) 和 Ramos (B) 全细胞裂解液中 CD79B 表达的 Western 印迹分析.
CD79B 抗体 (SN8): sc-18902. U-698-M (A) 和 Ramos (B) 全细胞裂解液中 CD79B 表达的 Western 印迹分析.

CD79B 抗体 (SN8): sc-18902

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寫評論提問

说明书
  • CD79B抗体(SN8)是小鼠单克隆IgG1 κ, 在2篇文献中引用，规格为200 µg/ml
  • 针对来自human来源的B-淋巴细胞白血病细胞的细胞膜
  • 推荐用于 human 来源的the extracellular portion of CD79B WB, IP, IF 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是CD79B Antibody (SN8) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与CD79B Antibody (SN8) 打包提供（请参阅下面的订购信息）。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

额外CD79抗体，包括CD79B

CD79（也称为Igα/Igβ）是一种由α链（称为CD79A或MB-1）和β链（称为CD79B或B29）组成的异二聚体。B细胞抗原受体复合物（BCR）是由CD79与膜免疫球蛋白（如IgM或IgD）结合形成的。IgM和IgD膜免疫球蛋白在CD79结合的作用下实现表面表达和抗原呈递功能。CD79A和CD79B的细胞质尾部均含有ITAM（免疫受体酪氨酸基激活）基序，它通过结合和激活酪氨酸激酶来启动BCR信号反应。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD79B 抗体 (SN8) 参考文献:

  1. 人 B-CLL 细胞中 CD79a（Ig alpha）和 CD79b（Ig beta）转录物的交替剪接。  |  Alfarano, A., et al. 1999. Curr Top Microbiol Immunol. 246: 241-6; discussion 247-8. PMID: 10396062
  2. 慢性淋巴细胞白血病中 CD79b 的表达。与 12 三体综合征和非典型免疫表型有关。  |  Schlette, E., et al. 2003. Arch Pathol Lab Med. 127: 561-6. PMID: 12708898
  3. 弥漫大 B 细胞淋巴瘤中的 CD79B 和 MYD88 基因突变。  |  Kim, Y., et al. 2014. Hum Pathol. 45: 556-64. PMID: 24444466
  4. CD5阳性弥漫性大B细胞淋巴瘤中的MYD88、CD79B和CARD11基因突变。  |  Takeuchi, T., et al. 2017. Cancer. 123: 1166-1173. PMID: 27915469
  5. CD79b 靶细胞用于 B 细胞淋巴瘤的嵌合抗原受体 T 细胞疗法  |  Ding, S., et al. 2020. Target Oncol. 15: 365-375. PMID: 32495161
  6. Polatuzumab vedotin：一种用于治疗弥漫大 B 细胞淋巴瘤的抗 CD79b 抗体药物结合物。  |  Bourbon, E. and Salles, G. 2020. Expert Opin Investig Drugs. 29: 1079-1088. PMID: 32700972
  7. 用于治疗复发/难治弥漫大 B 细胞淋巴瘤的抗 CD79b 抗体-药物共轭物 Polatuzumab vedotin。  |  Camus, V. and Tilly, H. 2021. Future Oncol. 17: 127-135. PMID: 32954807
  8. 弥漫性大 B 细胞淋巴瘤中 MYD88 和 CD79B 的致癌突变及其对临床实践的影响  |  Visco, C., et al. 2020. Cancers (Basel). 12: PMID: 33050534
  9. 用抗 CD79b 抗体调节 B 细胞可改善小鼠的实验性自身免疫性脑炎。  |  Renner, K., et al. 2022. Eur J Immunol. 52: 656-668. PMID: 34962287
  10. CD79A 和 CD79B 通过 B 细胞受体表面表达支持 IgM+ B 细胞健壮的机制  |  Huse, K., et al. 2022. J Immunol. 209: 2042-2053. PMID: 36426942

订购信息

产品名称产品编号规格价格数量收藏夹

CD79B 抗体 (SN8)

sc-18902
200 µg/ml
RMB2377.00

CD79B (SN8): m-IgG Fc BP-HRP 套装

sc-536612
200 µg Ab; 10 µg BP
RMB2662.00

CD79B (SN8): m-IgGκ BP-HRP 套装

sc-533768
200 µg Ab; 40 µg BP
RMB2662.00

CD79B (SN8): m-IgG1 BP-HRP 套装

sc-544707
200 µg Ab; 20 µg BP
RMB2662.00

CD79B 抗体 (SN8) FITC

sc-18902 FITC
200 µg/ml
RMB2482.00

CD79B 抗体 (SN8) PE

sc-18902 PE
200 µg/ml
RMB2580.00

I would like to get an unconjugated and FITC conjugated trial size sample of this antibody. Please let me know how to procced.

Asked by: Hittu
Thank you for your question. Please contact our Technical Service Department for more information on how to receive a free 10 ug sample of this monoclonal antibody.
Answered by: Technical Service
Date published: 2024-03-28

Can CD79B (SN8): sc-18902 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: cjMara
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD79B (SN8): sc-18902 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Well-rounded antibody for CD79BGreat choice for all your CD79B needs! It works great for both WB and Flow Cytometry.
Date published: 2017-02-07
Rated 5 out of 5 by from Positive signal in WB in Daudi whole cell lysatePositive signal in WB in Daudi whole cell lysate. -SCBT QC
Date published: 2015-07-04
Rated 5 out of 5 by from Strong band in WB in human peripheral blood cellsStrong band in WB in human peripheral blood cells. -SCBT Publication Review
Date published: 2015-06-27
Rated 5 out of 5 by from Strong signal strength in WB in human transfectedStrong signal strength in WB in human transfected 293T and Raji whole cell lysates. -SCBT QC
Date published: 2015-04-27
Rated 5 out of 5 by from Robust signal in WB in Ramos whole cell lysatesRobust signal in WB in Ramos whole cell lysates. -SCBT QC
Date published: 2015-04-12
Rated 5 out of 5 by from Good specificity in WB in NAMALWA and RamosGood specificity in WB in NAMALWA and Ramos whole cell lysates. -SCBT QC
Date published: 2015-03-22
Rated 5 out of 5 by from Good publishable data in IHC in human lymph nodesGood publishable data in IHC in human lymph nodes, PCM cells, and bone marrow. -SCBT Publication Review
Date published: 2015-01-12
Rated 5 out of 5 by from Nice FCM data of GANice FCM data of GA-10 cells. -SCBT QC
Date published: 2014-06-20
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CD79B 抗体 (SN8) is rated 5.0 out of 5 by 8.
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