Date published: 2025-9-6

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CD79B 抗体 (H-3): sc-373843

5.0(2)
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说明书
  • CD79B抗体(H-3)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 免疫human物种的代表全长CD79B的氨基酸1-229
  • 推荐用于 mouse, rat 和 human 来源的CD79B WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP是CD79B Antibody (H-3) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与CD79B Antibody (H-3) 搭配使用(请参阅下面的订购信息)。

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    関連項目

    CD79(也称为Igα/Igβ)是一种由α链(称为CD79A或MB-1)和β链(称为CD79B或B29)组成的异二聚体。B细胞抗原受体复合物(BCR)是由CD79与膜免疫球蛋白(如IgM或IgD)结合形成的。IgM和IgD膜免疫球蛋白在CD79结合的作用下实现表面表达和抗原呈递功能。CD79A和CD79B的细胞质尾部均含有ITAM(免疫受体酪氨酸基激活)基序,它通过结合和激活酪氨酸激酶来启动BCR信号反应。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    CD79B 抗体 (H-3) 参考文献:

    1. 慢性淋巴细胞白血病中广泛的 B29(CD79b)基因缺陷和表达缺失。  |  Thompson, AA., et al. 1999. Leuk Lymphoma. 32: 561-9. PMID: 10048429
    2. 家族性慢性淋巴细胞白血病的 B 细胞受体 B29 (CD79b) 基因分析。  |  Payelle-Brogard, B., et al. 1999. Blood. 94: 3516-22. PMID: 10552962
    3. 慢性淋巴细胞白血病 B 细胞的 B29(Igbeta,CD79b)基因突变导致 B 细胞受体信号传导异常。  |  Gordon, MS., et al. 2000. Proc Natl Acad Sci U S A. 97: 5504-9. PMID: 10792036
    4. B-CLL 细胞的 CD40 激活与细胞内 CD79b 水平升高和部分患者的 BCR 表达增加有关。  |  Minuzzo, S., et al. 2005. Leukemia. 19: 1099-101. PMID: 15830006
    5. CD79b单克隆抗体抑制体液免疫,CD79b是B淋巴细胞抗原受体的不变成分。  |  Nakamura, T., et al. 1996. Int J Hematol. 64: 39-46. PMID: 8757966
    6. 单克隆抗体 SN8(CD79b)在 B 细胞疾病中免疫球蛋白相关蛋白 B29 的表达。  |  Zomas, AP., et al. 1996. Leukemia. 10: 1966-70. PMID: 8946938
    7. 慢性淋巴细胞白血病中 B 细胞受体 B29 (CD79b) 基因的畸变。  |  Thompson, AA., et al. 1997. Blood. 90: 1387-94. PMID: 9269755
    8. 通过 Ig-beta(B29、CD79b)交联的抗原受体可在 CD40 激活的人类 B 细胞中诱导正负信号。  |  Van Kooten, C., et al. 1997. Clin Exp Immunol. 110: 509-15. PMID: 9409658
    9. 人类生长激素基因簇与 CD79b(Ig beta/B29)基因的物理联系。  |  Bennani-Baïti, IM., et al. 1998. Genomics. 48: 258-64. PMID: 9521881
    10. B29/Ig-beta (CD79B) 基因与大鼠和人类骨骼肌、钠通道和生长激素基因的物理联系。  |  Nakazato, S., et al. 1998. Genomics. 48: 363-8. PMID: 9545642

    订购信息

    产品名称产品编号规格价格数量收藏夹

    CD79B 抗体 (H-3)

    sc-373843
    200 µg/ml
    RMB2377.00

    CD79B (H-3): m-IgG Fc BP-HRP 套装

    sc-540405
    200 µg Ab; 10 µg BP
    RMB2662.00

    I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with CD79B (H-3): sc-373843?

    Asked by: TinTin
    We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Good Western Blot data of CD79B expression in nonGood Western Blot data of CD79B expression in non-transfected and human CD79B transfected 293T whole cell lysates. -SCBT QC
    Date published: 2015-02-09
    Rated 5 out of 5 by from Produced positive Western Blot data of CD79BProduced positive Western Blot data of CD79B expression in Ramos and NAMALWA whole cell lysates. -SCBT QC
    Date published: 2014-07-28
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    CD79B 抗体 (H-3) is rated 5.0 out of 5 by 2.
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