Date published: 2026-10-24

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CD71/TFRC/Transferrin Receptor 抗体 (DF1513): sc-7327

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说明书
  • CD71/TFRC/Transferrin Receptor抗体(DF1513)是小鼠单克隆IgG1 κ, 在19篇文献中引用,规格为200 µg/ml
  • 针对KG1急性髓细胞白血病细胞系
  • 推荐用于 human 来源的CD71 IF, IHC(P) 和 FCM检测
  • 可提供偶联藻红蛋白, FITC, Alexa Fluor® 488 或者Alexa Fluor® 647 的产品, 应用于IF, IHC(P)和FCM
  • 还可偶联Alexa Fluor® 405 用于IF, IHC(P) 和FCM
  • 看 CD71/TFRC/Transferrin Receptor (3B8 2A1): sc-32272,可查看有标记的 CD71/TFRC/Transferrin Receptor 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是CD71/TFRC/Transferrin Receptor Antibody (DF1513) 适用于 IHC(P) 应用。 的首选辅助检测试剂。这些试剂现与CD71/TFRC/Transferrin Receptor Antibody (DF1513) 打包提供(请参阅下面的订购信息)。
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関連項目

CD71,又称转铁蛋白受体(TFR),是一种二型膜糖蛋白,以二聚体形式存在,由两个相同的亚基组成。CD71结合两分子转铁蛋白和血清铁转运蛋白,通过受体介导的内吞作用指导细胞内铁的摄取。CD71通常以高水平表达于所有增殖细胞、网织细胞和红系前体。它不表达于休眠的白细胞,但在淋巴细胞、单核细胞和巨噬细胞激活时会上调表达。CD71也可以在大多数分裂细胞和脑内皮细胞中发现。另一种转铁蛋白受体TFR2也能介导结合转铁蛋白的铁的摄取。TFR2是一种二聚体,在肝脏以及肝细胞和红系前体中表达水平很高。TFR2基因的突变导致高铁负荷性遗传性血红蛋白病(HFE3),这是一种主要见于白种人的铁超载疾病。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD71/TFRC/Transferrin Receptor 抗体 (DF1513) 参考文献:

  1. 免疫抑制性CD71+红细胞损害了新生儿对感染的防御能力。  |  Elahi, S., et al. 2013. Nature. 504: 158-62. PMID: 24196717
  2. 转铁蛋白受体(CD71)与刺激的人和小鼠T细胞上Ki67表达的相关性:T细胞激活标记物的表达动力学。  |  Motamedi, M., et al. 2016. J Immunol Methods. 437: 43-52. PMID: 27555239
  3. 疟原虫对表达转铁蛋白受体1(CD71)的网织红细胞的不健康吸引力。  |  Malleret, B., et al. 2017. Int J Parasitol. 47: 379-383. PMID: 28414070
  4. CD71系膜IgA1受体与IgA肾病的进展  |  Jhee, JH., et al. 2021. Transl Res. 230: 34-43. PMID: 33122053
  5. CD71+红细胞在调节免疫反应中的作用。  |  Grzywa, TM., et al. 2021. Pharmacol Ther. 228: 107927. PMID: 34171326
  6. 培养的CD71+红细胞调节宿主免疫反应。  |  Alshalani, A., et al. 2023. Transfus Med. 33: 257-262. PMID: 36919690
  7. CD71+红细胞抑制T细胞效应功能,并预测病毒相关实体瘤患者的免疫治疗结果。  |  Bozorgmehr, N., et al. 2023. J Immunother Cancer. 11: PMID: 37236637
  8. CD71介导的脂质体砷镍复合物与全反式维甲酸联合治疗急性早幼粒细胞白血病。  |  Liu, X., et al. 2023. Asian J Pharm Sci. 18: 100826. PMID: 37583710
  9. 营养对ILC3维持和功能的影响集中在细胞内CD71-铁轴上。  |  Xiong, L., et al. 2023. Nat Immunol. 24: 1671-1684. PMID: 37709985
  10. 间变性甲状腺癌细胞通过降低CD71水平来提高铁超负荷耐受性。  |  D'Aprile, S., et al. 2023. J Transl Med. 21: 780. PMID: 37924062

订购信息

产品名称产品编号规格价格数量收藏夹

CD71/TFRC/Transferrin Receptor 抗体 (DF1513)

sc-7327
200 µg/ml
CNY2422.00

CD71/TFRC/Transferrin Receptor (DF1513): m-IgG Fc BP-HRP 套装

sc-536557
200 µg Ab; 10 µg BP
CNY2715.00

CD71/TFRC/Transferrin Receptor (DF1513): m-IgGκ BP-HRP 套装

sc-533708
200 µg Ab; 40 µg BP
CNY2715.00

CD71/TFRC/Transferrin Receptor (DF1513): m-IgG1 BP-HRP 套装

sc-544673
200 µg Ab; 20 µg BP
CNY2715.00

CD71/TFRC/Transferrin Receptor 抗体 (DF1513) Alexa Fluor® 405

sc-7327 AF405
200 µg/ml
CNY2738.00

CD71/TFRC/Transferrin Receptor 抗体 (DF1513) Alexa Fluor® 488

sc-7327 AF488
200 µg/ml
CNY2738.00

CD71/TFRC/Transferrin Receptor 抗体 (DF1513) Alexa Fluor® 647

sc-7327 AF647
200 µg/ml
CNY2738.00

CD71/TFRC/Transferrin Receptor 抗体 (DF1513) FITC

sc-7327 FITC
200 µg/ml
CNY2527.00

CD71/TFRC/Transferrin Receptor 抗体 (DF1513) PE

sc-7327 PE
200 µg/ml
CNY2625.00

Can CD71 (DF1513): sc-7327 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: DefinitelyNotMatt
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD71 (DF1513): sc-7327 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by amaya66 from band correctlyUsed for IHC and IF of paraffin human placenta tissue, antibody with good results.
Date published: 2017-02-12
Rated 5 out of 5 by Randy McDonald from Nice FCM signalWe used this antibody in a FCM experiment and got a very nice signal
Date published: 2017-01-24
Rated 5 out of 5 by Xaviers from thanksUsing this antibody with HeLa and HEK-293T cells to obtain better characteristics, published IF and WB data, the results of my experiments passed the acceptance,
Date published: 2017-01-17
Rated 5 out of 5 by TS from Published IF and WB data using this antibodyPublished IF and WB data using this antibody with HeLa & HEK-293T cells. -SCBT Publication Review
Date published: 2015-04-25
Rated 5 out of 5 by HF from FACS using human bone marrowFACS using human bone marrow-derived MSC progenitor cells. -SCBT Publication Review
Date published: 2015-02-24
Rated 5 out of 5 by SM from Used for immunoperoxidase staining of humanUsed for immunoperoxidase staining of human dermal fibroblasts & keratinocytes. -SCBT Publication Review
Date published: 2015-02-19
Rated 5 out of 5 by TO from Beautiful immunoperoxidase cytoplasmic andBeautiful immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human placenta tissue. -SCBT QC
Date published: 2015-01-27
Rated 5 out of 5 by JT from Superb FCM data of CCRFSuperb FCM data of CCRF-CEM cells. -SCBT QC
Date published: 2014-02-19
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CD71/TFRC/Transferrin Receptor 抗体 (DF1513) is rated 5.0 out of 5 by 8.
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