Date published: 2026-10-24

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CD71/TFRC/Transferrin Receptor 抗体 (Ber-T9): sc-19675

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说明书
  • CD71/TFRC/Transferrin Receptor抗体(Ber-T9)是小鼠单克隆IgG1 κ, 在3篇文献中引用,规格为200 µg/ml
  • 针对human来源的HPB-ALL细胞系
  • 推荐用于 human 来源的CD71 IF 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 CD71/TFRC/Transferrin Receptor (3B8 2A1): sc-32272,可查看有标记的 CD71/TFRC/Transferrin Receptor 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 1 BP-HRP">m-IgG1 BP-HRP和m-IgGκ BP-HRP是CD71/TFRC/Transferrin Receptor Antibody (Ber-T9). 的首选辅助检测试剂。这些试剂现与CD71/TFRC/Transferrin Receptor Antibody (Ber-T9) 打包提供(请参阅下面的订购信息)。
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関連項目

CD71,又称转铁蛋白受体(TFR),是一种二型膜糖蛋白,以二聚体形式存在,由两个相同的亚基组成。CD71结合两分子转铁蛋白和血清铁转运蛋白,通过受体介导的内吞作用指导细胞内铁的摄取。CD71通常以高水平表达,在所有增殖细胞、网织细胞和红系前体上表达。它不在休息的白细胞上表达,但在淋巴细胞、单核细胞和巨噬细胞激活时被上调。CD71也可以在大多数分裂细胞和脑内皮细胞上发现。另一种转铁蛋白受体TFR2也能介导转铁蛋白结合的铁的摄取。TFR2是一种二亚基体的同源二聚体,在肝脏以及肝细胞和红系前体中表达水平很高。TFR2基因的突变导致遗传性血色素沉积症类型III(HFE3),这是一种主要见于白种人的铁超载疾病。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD71/TFRC/Transferrin Receptor 抗体 (Ber-T9) 参考文献:

  1. 新生儿CD71+红细胞不会改变小鼠脓毒症的死亡率。  |  Wynn, JL., et al. 2015. J Immunol. 195: 1064-70. PMID: 26101326
  2. CD71+红细胞抑制细胞损害对百日咳博德特氏菌的适应性免疫力  |  Namdar, A., et al. 2017. Sci Rep. 7: 7728. PMID: 28798335
  3. 在骨髓增生异常综合征中,CD71脱落与网状细胞线粒体清除脱钩。  |  Zhang, Q., et al. 2019. Leukemia. 33: 217-229. PMID: 30050123
  4. CD71+VISTA+红细胞通过TGF-β促进调节性T细胞的发展和功能。  |  Shahbaz, S., et al. 2018. PLoS Biol. 16: e2006649. PMID: 30550561
  5. HPV-E6蛋白富集的CD71+群体促进宫颈癌细胞的癌症侵袭性和放射抗性  |  Leung, TH., et al. 2019. Mol Cancer Res. 17: 1867-1880. PMID: 31235657
  6. CD45对CD71+TER119+红系祖细胞的调节。  |  Shim, YA., et al. 2020. Exp Hematol. 86: 53-66.e1. PMID: 32450207
  7. 肝细胞癌中肿瘤内CD45+CD71+红细胞诱导免疫耐受并预测肿瘤复发。  |  Chen, J., et al. 2021. Cancer Lett. 499: 85-98. PMID: 33279623
  8. CD71特异性适配体与单甲基金雀花素E结合,用于治疗葡萄膜黑色素瘤。  |  Zhang, H., et al. 2022. ACS Appl Mater Interfaces. 14: 32-40. PMID: 34928139
  9. 成人脓毒症中CD71+红细胞扩张:潜在原因及其在预后和医院感染预测中的作用。  |  Zhao, GJ., et al. 2022. Front Immunol. 13: 830025. PMID: 35251018
  10. 人胎儿肝实质 CD71+ 细胞具有 AIRE 和组织特异性抗原基因表达  |  Perik-Zavodskii, R., et al. 2022. Genes (Basel). 13: PMID: 35886060

订购信息

产品名称产品编号规格价格数量收藏夹

CD71/TFRC/Transferrin Receptor 抗体 (Ber-T9)

sc-19675
200 µg/ml
CNY2422.00

CD71/TFRC/Transferrin Receptor (Ber-T9): m-IgG Fc BP-HRP 套装

sc-536631
200 µg Ab; 10 µg BP
CNY2715.00

CD71/TFRC/Transferrin Receptor (Ber-T9): m-IgGκ BP-HRP 套装

sc-533788
200 µg Ab; 40 µg BP
CNY2715.00

CD71/TFRC/Transferrin Receptor (Ber-T9): m-IgG1 BP-HRP 套装

sc-544718
200 µg Ab; 20 µg BP
CNY2715.00

CD71/TFRC/Transferrin Receptor 抗体 (Ber-T9) FITC

sc-19675 FITC
200 µg/ml
CNY2527.00

CD71/TFRC/Transferrin Receptor 抗体 (Ber-T9) PE

sc-19675 PE
200 µg/ml
CNY2625.00

Does this antibody block the transferrin binding?

Asked by: WR790
Thank you for your question. For assistance please contact Technical Service. Please call 800-457-3801 or email [email protected].
Answered by: BlakeJ
Date published: 2026-03-25

Can CD71 (Ber-T9): sc-19675 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: AbPolly
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD71 (Ber-T9): sc-19675 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by JL from Produced robust immunofluorescence membraneProduced robust immunofluorescence membrane staining in methanol-fixed Jurkat cells. -SCBT QC
Date published: 2015-05-09
Rated 4 out of 5 by FL from Worked well for Flow with human skin samplesWorked well for Flow with human skin samples. -SCBT Publication Review
Date published: 2015-04-11
Rated 4 out of 5 by CJ from FACS with human breast skin extractsFACS with human breast skin extracts. -SCBT Publication Review
Date published: 2015-01-27
Rated 4 out of 5 by ET from Wonderful FCM data of PMAWonderful FCM data of PMA-stimulated Jurkat cells. -SCBT QC
Date published: 2014-07-30
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CD71/TFRC/Transferrin Receptor 抗体 (Ber-T9) is rated 4.0 out of 5 by 4.
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