Date published: 2025-9-8
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CD57 Antibody (NK-1) - Western Blotting - Image 359442
CD57 抗体 (NK-1): sc-6261. K-562 (A) 和 SK-N-SH (B) 全细胞裂解液中 CD57 表达的 Western 印迹分析.
CD57 抗体 (NK-1): sc-6261. K-562 (A) 和 SK-N-SH (B) 全细胞裂解液中 CD57 表达的 Western 印迹分析.

CD57 抗体 (NK-1): sc-6261

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说明书
  • CD57 抗体 NK-1 是小鼠单克隆 IgM κ，CD57抗体, 在5篇文献中引用，规格为200 µg/ml
  • 针对human外周血单核细胞
  • 推荐用于 mouse, rat 和 human 来源的CD57 WB, IP, IF, IHC(P) 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 关于如何获取CD57 (NK-1): sc-6261的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 目前，我们还没有完成CD57 抗体 (NK-1)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

CD57抗体（NK-1）是一种IgM κ小鼠单克隆CD57抗体（也称为CD57抗体），可通过WB、IP、IF、IHC（P）和FCM检测来自小鼠、大鼠和人类的CD57蛋白。CD57抗体（NK-1）既可以是非偶联的抗CD57抗体形式，也可以是多种偶联形式的抗CD57抗体，包括PE、FITC。通过使用单克隆抗体，已经鉴定了超过100种细胞表面标记物。其中许多标记物已被证明可用于识别混合群体中的特定亚群。因此，这些分子已被指定为"分化簇"（CD）。细胞表面显示的自然杀伤（NK）细胞标记CD57（也称为Leu7）的T淋巴细胞可通过其颗粒淋巴细胞形态和其在艾滋病患者和骨髓移植受者中的克隆扩增与其他T细胞亚群区分开来。CD57阳性细胞还被证明可定位于某些肿瘤的病灶，并且在患有类风湿性关节炎的患者的滑液中检测到大量的细胞。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD57 抗体 (NK-1) 参考文献:

  1. [白细胞的表型和功能特征--CD 系统]。  |  Holter, W., et al. 1991. Wien Klin Wochenschr. 103: 247-62. PMID: 2068816
  2. 人类自然杀伤细胞和T淋巴细胞中的CD57。  |  Kared, H., et al. 2016. Cancer Immunol Immunother. 65: 441-52. PMID: 26850637
  3. CXCL12-CXCR4介导1型糖尿病进展中的CD57+ CD8+ T细胞反应。  |  Zhong, T., et al. 2024. J Autoimmun. 143: 103171. PMID: 38306953
  4. CD4+CD57+衰老T细胞是系统性红斑狼疮发病机制的启动子，溶细胞Bcl-2抑制剂具有治疗潜力。  |  Jiang, J., et al. 2024. Eur J Immunol. 54: e2350603. PMID: 38752316
  5. CD57定义了一种新型的癌症干细胞，可驱动弥漫性儿童型高等级胶质瘤的侵袭。  |  Qi, L., et al. 2024. Br J Cancer. 131: 258-270. PMID: 38834745
  6. 同种异体骨髓移植后，移植物抗宿主疾病患者体内 CD8+S6F1+ 和 CD8+CD57+ 细胞明显增加。  |  Fukuda, H., et al. 1994. Bone Marrow Transplant. 13: 181-5. PMID: 7515741
  7. CD11/CD18 小组报告：猪 CD 研讨会。  |  Kim, YB., et al. 1994. Vet Immunol Immunopathol. 43: 289-91. PMID: 7531911
  8. 结直肠癌患者肿瘤部位增多的 CD57+ T 细胞的来源。  |  Okada, T., et al. 1995. Clin Exp Immunol. 102: 159-66. PMID: 7554383
  9. 亮7（CD57）反应性可将结节性淋巴细胞占优势的霍奇金病与结节性硬化性霍奇金病, 富含T细胞的B细胞淋巴瘤和滤泡淋巴瘤区分开来。  |  Kamel, OW., et al. 1993. Am J Pathol. 142: 541-6. PMID: 7679553
  10. 类风湿性关节炎患者 CD3+, CD57+ 淋巴细胞比例增加。与病程相关。  |  Dupuy d'Angeac, A., et al. 1993. Arthritis Rheum. 36: 608-12. PMID: 7683880
  11. 表达 CD57 抗原的人类 CD8+ 细胞的表型特性和细胞毒性功能。  |  Yamashita, N., et al. 1993. Nat Immun. 12: 79-91. PMID: 7686417
  12. CD57+CD28-T细胞扩增之谜--能量还是活化？  |  Kern, F., et al. 1996. Clin Exp Immunol. 104: 180-4. PMID: 8603525

订购信息

产品名称产品编号规格价格数量收藏夹

CD57 抗体 (NK-1)

sc-6261
200 µg/ml
RMB2377.00

CD57 抗体 (NK-1) FITC

sc-6261 FITC
200 µg/ml
RMB2482.00

CD57 抗体 (NK-1) PE

sc-6261 PE
200 µg/ml
RMB2580.00

Can CD57 (NK-1): sc-6261 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: TinTin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD57 (NK-1): sc-6261 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Good with IHCWorks fine with IHC (pH 9, 1:100) on human tonsils and brain (5 µm FFPE).
Date published: 2018-04-12
Rated 4 out of 5 by from Good in IHCUsed in mouse tissue by IHC and got good staining.
Date published: 2017-08-28
Rated 5 out of 5 by from Great monoclonal antibodyCD57 Antibody (NK-1) is versatile and can be applied to many applications including WB, IP, IF, IHC(P) and FCM. Observed very good results by WB, IHCP and FCM
Date published: 2017-02-09
Rated 5 out of 5 by from Published IHC data for use in human colonPublished IHC data for use in human colon wall tissues. -SCBT Publication Review
Date published: 2015-05-02
Rated 5 out of 5 by from Good IF data with human Hodgkin lymphomaGood IF data with human Hodgkin lymphoma. -SCBT Publication Review
Date published: 2015-04-12
Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB with some nonspecific binding. -SCBT QC
Date published: 2015-04-07
Rated 4 out of 5 by from Good immunoperoxidase membrane staining inGood immunoperoxidase membrane staining in formalin-fixed, paraffin-embedded normal human lymph node at high magnification. -SCBT QC
Date published: 2015-03-12
Rated 4 out of 5 by from Produced great FCM data for CCRFProduced great FCM data for CCRF-CEM cells. -SCBT QC
Date published: 2015-01-13
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CD57 抗体 (NK-1) is rated 4.4 out of 5 by 8.
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