Date published: 2025-9-7

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CD52 抗体 (HI186): sc-51560

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说明书
  • CD52 抗体 HI186 是小鼠单克隆 IgG2b κ,CD52抗体, 在2篇文献中引用,规格为100 µg/ml
  • 针对human扁桃体组织/细胞制备
  • 推荐用于 human 来源的precursor and mature CD52 WB, IP, IF, IHC(P) 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 关于如何获取CD52 (HI186): sc-51560免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP 是 CD52 抗体 (HI186) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CD52 抗体 (HI186) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

CD52抗体(HI186)是一种IgG2b κ小鼠单克隆CD52抗体(也称为CD52抗体),可通过WB、IP、IF、IHC(P)和FCM检测人类来源的CD52蛋白。CD52抗体(HI186)既可以是非偶联的抗CD52抗体形式,也可以是多种偶联形式的抗CD52抗体,包括PE、FITC。CD52是一种糖脂磷脂酰肌醇(GPI)结合的表面抗原,在男性生殖道内表面细胞、胸腺细胞、淋巴细胞、单核细胞和巨噬细胞上的表达水平很高。它在淋巴恶性肿瘤上的表达水平也不一样。在精子成熟过程中,经过生殖道的精子从内表面细胞获得CD52,被排入精浆中。CD52可以在附睾精子表面和射精液中检测到,但不能在精子发生细胞或睾丸精子表面检测到。CD52的肽骨架由12个氨基酸组成,被认为只是后翻译修饰(如GPI锚定和N-糖基化)的支架。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD52 抗体 (HI186) 参考文献:

  1. CD52 抗原--综述  |  Domagała, A. and Kurpisz, M. 2001. Med Sci Monit. 7: 325-31. PMID: 11257744
  2. 浆细胞增殖性疾病中浆细胞上 CD52 的表达。  |  Kumar, S., et al. 2003. Blood. 102: 1075-7. PMID: 12714489
  3. 首次全合成 GPI 锚定肽。  |  Xue, J., et al. 2003. J Org Chem. 68: 4020-9. PMID: 12737586
  4. 含有酸性岩藻糖基连接的 CD52 糖肽的化学合成。  |  Shao, N., et al. 2003. J Org Chem. 68: 9003-11. PMID: 14604374
  5. 人类男性生殖道 CD52 中可能存在 O 链碳水化合物。  |  Hasegawa, A., et al. 2004. J Reprod Immunol. 62: 91-100. PMID: 15288185
  6. 在不孕妇女中检测到精子动员抗体的抗原表位。  |  Hasegawa, A. and Koyama, K. 2005. J Reprod Immunol. 67: 77-86. PMID: 16107278
  7. 人类 GPI-anchored 抗原 CD52 的不同糖型与白细胞和精子膜中的脂质微域有不同的关联。  |  Ermini, L., et al. 2005. Biochem Biophys Res Commun. 338: 1275-83. PMID: 16266689
  8. 阿仑单抗靶向清除CD52可改善过敏性气道高反应性和肺部炎症。  |  Shafiei-Jahani, P., et al. 2021. Mucosal Immunol. 14: 899-911. PMID: 33731828
  9. CD52 mRNA表达可预测黑色素瘤的预后和对免疫检查点阻断的反应。  |  de Vos-Hillebrand, L., et al. 2024. Pigment Cell Melanoma Res. 37: 309-315. PMID: 37975535
  10. 表面CD52、CD84和PTGER2标记来自癌症患者和接受G-CSF治疗的供体的成熟中性粒细胞-MDSC。  |  Pettinella, F., et al. 2024. Cell Rep Med. 5: 101380. PMID: 38242120
  11. CLL中的T细胞功能障碍是通过CLL细胞上Siglec-10配体CD24和CD52的表达介导的。  |  van Bruggen, JAC., et al. 2024. Blood Adv. 8: 4633-4646. PMID: 39042920
  12. 射出精子上的人类附睾分泌蛋白 CD52:与精液特征的相关性及其抗体的影响。  |  Yeung, CH., et al. 1997. Mol Hum Reprod. 3: 1045-51. PMID: 9464849

订购信息

产品名称产品编号规格价格数量收藏夹

CD52 抗体 (HI186)

sc-51560
100 µg/ml
RMB2377.00

CD52 (HI186): m-IgG Fc BP-HRP 套装

sc-536848
100 µg Ab; 10 µg BP
RMB2662.00

CD52 (HI186): m-IgGκ BP-HRP 套装

sc-534015
100 µg Ab; 40 µg BP
RMB2662.00

CD52 抗体 (HI186) FITC

sc-51560 FITC
100 tests in 2 ml
RMB2482.00

CD52 抗体 (HI186) PE

sc-51560 PE
100 tests in 2 ml
RMB2580.00

Can CD52 (HI186): sc-51560 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Professor Griffin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD52 (HI186): sc-51560 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Excellent Staining Quality with SANTA's CD52 AntibI recently used the CD52 antibody from SANTA for flow cytometry and was very pleased with the results. The staining was clear and consistent, making this product highly reliable and effective for my research needs. Highly recommended!
Date published: 2024-04-16
Rated 5 out of 5 by from Good for Immunoperoxidase stainingAntibody has been used for Immunoperoxidase staining in published research. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from GREAT COMPANY for RUO ProductsI have been purchasing several antibodies from Santa Cruz for the past two years. Excellent customer Service.
Date published: 2020-07-15
Rated 5 out of 5 by from 抗体很好this antibody can get clear and uniform band in western blot
Date published: 2017-09-04
Rated 5 out of 5 by from Used in IF and got good stainingUsed in IF and got good staining.
Date published: 2015-07-27
Rated 5 out of 5 by from Excellent indirect FCM data of human peripheralExcellent indirect FCM data of human peripheral blood leukocytes stained with CD52 . -SCBT QC
Date published: 2013-12-18
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CD52 抗体 (HI186) is rated 5.0 out of 5 by 6.
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