Date published: 2025-9-7
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CD48 Antibody (4H9) - Western Blotting - Image 358958
CD48 抗体 (4H9): sc-8397. 对 Raji 全细胞裂解液中 CD48 表达的 Western 印迹分析.
CD48 抗体 (4H9): sc-8397. 对 Raji 全细胞裂解液中 CD48 表达的 Western 印迹分析.

CD48 抗体 (4H9): sc-8397

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说明书
  • CD48抗体(4H9)是小鼠单克隆IgG1 κ, 在5篇文献中引用，规格为200 µg/ml
  • 针对受刺激的human白细胞
  • 推荐用于 mouse, rat 和 human 来源的CD48 WB, IP, IF, FCM 和 ELISA检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • m-IgG Fc BP-HRP和m-IgGκ BP-HRP是CD48 Antibody (4H9) 适用于 WB 应用。 的首选辅助检测试剂，这些试剂现与CD48 Antibody (4H9) 打包提供（请参阅下面的订购信息）。

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研究信息

関連項目

CD48是一种GPI锚定的糖蛋白，可以作为CD2的低亲和力受体。CD48在所有外周血T、B和空白细胞、胸腺细胞、嗜酸性粒细胞、骨髓细胞和一些上皮细胞上均表达。大鼠CD48可在造血细胞和内皮细胞上发现，而小鼠CD48可在胸腺细胞、淋巴结细胞、大多数巨噬细胞和骨髓细胞上发现。CD48已被证明与酪氨酸激酶Lck有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD48 抗体 (4H9) 参考文献:

  1. CD48受体介导金黄色葡萄球菌人类和鼠类嗜酸性粒细胞的活化。  |  Minai-Fleminger, Y., et al. 2014. Clin Exp Allergy. 44: 1335-46. PMID: 25255823
  2. CD48在调节免疫和耐受中的作用。  |  McArdel, SL., et al. 2016. Clin Immunol. 164: 10-20. PMID: 26794910
  3. CD48是影响胶质瘤预后的免疫调节的关键分子。  |  Zou, C., et al. 2019. Onco Targets Ther. 12: 4181-4193. PMID: 31213836
  4. AML1-ETO通过CD48抑制急性髓细胞白血病的免疫逃逸。  |  Wang, Z., et al. 2021. Leuk Lymphoma. 62: 937-943. PMID: 33225787
  5. GDF15通过肝细胞癌中调节性T细胞上的CD48诱导免疫抑制。  |  Wang, Z., et al. 2021. J Immunother Cancer. 9: PMID: 34489334
  6. 表达CD48的非小细胞肺癌细胞易受自然杀伤细胞介导的细胞毒性作用。  |  Park, EJ., et al. 2022. Arch Pharm Res. 45: 1-10. PMID: 34905179
  7. KDM6A介导的CD38/CD48表观遗传调控介导多发性骨髓瘤中的NK细胞反应。  |  Liu, J., et al. 2024. Nat Commun. 15: 1367. PMID: 38355622
  8. 巨噬细胞介导的吞噬作用抑制了适应性NK细胞的扩张，而2B4-CD48则抑制了这种吞噬作用。  |  Li, R., et al. 2024. Cell Rep. 43: 113800. PMID: 38386559
  9. CCR7和CD48作为小儿肾移植后急性排斥反应中M1巨噬细胞的预测靶标。  |  Zhang, J., et al. 2024. J Immunol Res. 2024: 6908968. PMID: 38957433
  10. CD48的功能及其受EB病毒的调控。  |  Thorley-Lawson, DA., et al. 1993. Biochem Soc Trans. 21: 976-80. PMID: 8132103

订购信息

产品名称产品编号规格价格数量收藏夹

CD48 抗体 (4H9)

sc-8397
200 µg/ml
RMB2377.00

CD48 (4H9): m-IgG Fc BP-HRP 套装

sc-536562
200 µg Ab; 10 µg BP
RMB2662.00

CD48 (4H9): m-IgGκ BP-HRP 套装

sc-533713
200 µg Ab; 40 µg BP
RMB2662.00

CD48 抗体 (4H9) FITC

sc-8397 FITC
200 µg/ml
RMB2482.00

CD48 抗体 (4H9) PE

sc-8397 PE
200 µg/ml
RMB2580.00

Can CD48 (4H9): sc-8397 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: cjMara
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD48 (4H9): sc-8397 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from Well-rounded antibody for CD48This antibody does it all! It's good for Western blot and IF, but it's also really good for Flow cytometry. A great choice for all your CD48 detection needs!
Date published: 2017-02-03
Rated 4 out of 5 by from Good Western with heavy signal achieved usingGood Western with heavy signal achieved using human CD48 transfected 293T whole cell lysate. -SCBT QC
Date published: 2015-07-11
Rated 4 out of 5 by from Produced great immunofluorescence membraneProduced great immunofluorescence membrane staining in methanol-fixed IB4 cells. -SCBT QC
Date published: 2015-05-27
Rated 5 out of 5 by from Published good quality flow cytometry dataPublished good quality flow cytometry data in mouse NK92-C1, 293, BaF3, P815, and primary NK cells. -SCBT Publication Review
Date published: 2015-05-23
Rated 4 out of 5 by from Great FCM data of human peripheral bloodGreat FCM data of human peripheral blood leukocytes. -SCBT QC
Date published: 2015-05-10
Rated 4 out of 5 by from Robust WB band achieved using IB4 wholeRobust WB band achieved using IB4 whole cell lysate. -SCBT QC
Date published: 2015-05-01
Rated 5 out of 5 by from Publishable Western blot results using humanPublishable Western blot results using human SSChigh and CCR3+. -SCBT Publication Review
Date published: 2015-02-12
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CD48 抗体 (4H9) is rated 4.4 out of 5 by 7.
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