Date published: 2025-9-6

021-6093-6350

SCBT Portrait Logo
Seach Input

CD45 抗体 (YAML 501.4): sc-65344

4.8(4)
寫評論提問

说明书
  • CD45 抗体 YAML 501.4 是大鼠单克隆 IgG2a, 在1篇文献中引用,提供 200 µg/ml
  • 针对急性髓细胞白血病细胞(human来源)
  • 推荐用于 human 来源的CD45 (LCA) molecule expressed on all lymphocytes WB, IP, IF 和 FCM检测
  • 还可偶联藻红蛋白 以及 FITC 用于IF, IHC(P) 和 FCM
  • 看 CD45 (35-Z6): sc-1178,可查看有标记的 CD45 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成CD45 抗体 (YAML 501.4)的首选二抗检测试剂的鉴定。这项工作正在进行中。

快捷链接

関連項目

CD45已被鉴定为一种跨膜糖蛋白,在造血细胞中广泛表达。CD45的多种异构体根据细胞类型分布在整个免疫系统中。这些异构体的产生是由于外显子4、5和6的选择性剪接。相应的蛋白质结构域的特征在于特异性针对CD45RA(外显子4)、CD45RB(外显子5)、CD45RC(外显子6)和CD45RO(外显子4至6被剪接掉)的单克隆抗体的结合。这些异构体的变异局限于CD45的细胞外结构域,而细胞内结构域则是保守的。CD45作为磷酸酪氨酸磷酸酶发挥作用,这是TCR/CD3复合物有效诱导酪氨酸磷酸化的重要组成部分。CD45的酪氨酸磷酸酶活性包含在其保守的细胞内结构域中。TCR/CD3复合物利用Src和Syk家族蛋白酪氨酸激酶来启动信号级联反应。这两个家族的几个成员,包括Lck、Fyn和ZAP-70,已被证实为CD45的生理底物。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

CD45 抗体 (YAML 501.4)

sc-65344
200 µg/ml
RMB2377.00

CD45 抗体 (YAML 501.4) FITC

sc-65344 FITC
200 µg/ml
RMB2482.00

CD45 抗体 (YAML 501.4) PE

sc-65344 PE
200 µg/ml
RMB2580.00

Can CD45 Antibody (YAML 501.4): sc-65344 be used for identifying mouse white blood cells in a mouse blood sample?

Asked by: Shayy1
Thank you for your question. CD45 Antibody (YAML 501.4): sc-65344 is only recommended for detection of CD45 (LCA) molecule expressed on all lymphocytes of human origin by WB, IP, IF and FCM.
Answered by: Tech Support Europe
Date published: 2020-09-01

Can CD45 (YAML 501.4): sc-65344 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: jenniferc
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD45 (YAML 501.4): sc-65344 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_30, h_9CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_65344, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 106ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Versatile Antibody for Human SamplesVersatile antibody for use in Human samples, can be used in WB, IP, Flow, and more. Strong signal with no background.
Date published: 2017-02-07
Rated 4 out of 5 by from PE conjugated works well for FlowPE conjugated works well for Flow.
Date published: 2015-10-29
Rated 5 out of 5 by from Produced excellent Indirect FCM data forProduced excellent Indirect FCM data for human peripheral blood leukocytes stained with CD45 . -SCBT QC
Date published: 2015-06-01
Rated 5 out of 5 by from Superb FCM data of Jurkat cellsSuperb FCM data of Jurkat cells. -SCBT QC
Date published: 2014-10-13
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_65344, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
CD45 抗体 (YAML 501.4) is rated 4.8 out of 5 by 4.
  • y_2025, m_8, d_30, h_9
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_4
  • loc_zh_CN, sid_65344, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 106ms
  • REVIEWS, PRODUCT