Date published: 2025-9-7

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CD35 抗体 (Ber-MAC-DRC): sc-19662

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说明书
  • CD35抗体(Ber-MAC-DRC)是小鼠单克隆mouse IgG1 κ (kappa轻链),规格为200 µg/ml
  • 免疫human物种的CD35
  • 推荐用于 human 来源的CD35, receptor for the C3b fragment WB, IP, IF 和 IHC(P)检测
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 CD35 抗体 (Ber-MAC-DRC) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CD35 抗体 (Ber-MAC-DRC) 组合成套装提供。 (请参阅下面的订购信息)。

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    CD35,又称为补体受体1(CR1),可作为补体成分C3b和C4b的受体,从而介导中性粒细胞和单核细胞对具有C3b或C4b包被颗粒的吞噬。CD35表达于粒细胞、单核细胞、B细胞、一些NK细胞和红细胞。CD35被认为与系统性红斑狼疮(SLE)有关,SLE是一种慢性系统性自身免疫性疾病,其特征是产生针对核、细胞质和细胞表面抗原的广谱自身抗体,以及免疫复合物超负荷。SLE患者的白细胞细胞表面CD35的蛋白水解切割增加。序列分析表明Crry可能是人类基因CR1编码的CD35抗原的小鼠遗传同源物。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    CD35 抗体 (Ber-MAC-DRC) 参考文献:

    1. 补体受体CD21/CD35在B淋巴细胞活化和存活中的作用。  |  Carroll, M. 1999. Curr Top Microbiol Immunol. 246: 63-8; discussion 69. PMID: 10396040
    2. 补体受体1型(CR1/CD35)的结构、遗传多态性、表达和生物学功能。  |  Liu, D. and Niu, ZX. 2009. Immunopharmacol Immunotoxicol. 31: 524-35. PMID: 19874218
    3. 补体受体 1 型(C3b/C4b 受体;CD35)和补体受体 2 型(C3d/天疱疮病毒受体;CD21)。  |  Fearon, DT. and Ahearn, JM. 1990. Curr Top Microbiol Immunol. 153: 83-98. PMID: 2153507
    4. 人类C3补体受体1型(CR1,CD35)和2型(CR2,CD21)的缺陷。  |  Kazatchkine, MD. and Fearon, DT. 1990. Immunodefic Rev. 2: 17-41. PMID: 2164822
    5. 类风湿性关节炎中补体调节蛋白 CD55、CD59、CD35 和 CD46 的表达。  |  Piccoli, AK., et al. 2011. Rev Bras Reumatol. 51: 503-10. PMID: 21953001
    6. 通过同时定量分析,中性粒细胞的CD35和CD64可以区分儿童细菌和病毒感染。  |  Lu, L., et al. 2019. Med Sci Monit. 25: 7728-7734. PMID: 31612870
    7. 内脏利什曼病患者的白细胞中1型(CR1/CD35)和3型(CR3/CD11b)补体受体的表达调节。  |  Campelo, CM., et al. 2020. Exp Parasitol. 218: 107970. PMID: 32828829
    8. CD35基因的遗传多态性对肝细胞癌的易感性和预后产生影响。  |  Luo, L., et al. 2021. Front Oncol. 11: 700711. PMID: 34422654
    9. CD35+滤泡树突状细胞的分离及其在B细胞向IgA+GL7+细胞分化中的作用。  |  Hikosaka-Kuniishi, M., et al. 2022. Immunol Lett. 243: 53-60. PMID: 35167919
    10. 补体系统的 C3 阶调节蛋白 CD35(CR1), CD46(MCP)和 CD55(DAF)在血液恶性肿瘤中的分布。  |  Seya, T., et al. 1994. Leuk Lymphoma. 12: 395-400. PMID: 7514063

    订购信息

    产品名称产品编号规格价格数量收藏夹

    CD35 抗体 (Ber-MAC-DRC)

    sc-19662
    200 µg/ml
    RMB2377.00

    CD35 (Ber-MAC-DRC): m-IgG Fc BP-HRP 套装

    sc-536628
    200 µg Ab; 10 µg BP
    RMB2662.00

    CD35 (Ber-MAC-DRC): m-IgGκ BP-HRP 套装

    sc-533785
    200 µg Ab; 40 µg BP
    RMB2662.00

    CD35 (Ber-MAC-DRC): m-IgG1 BP-HRP 套装

    sc-544717
    200 µg Ab; 20 µg BP
    RMB2662.00

    I am using CD35 (Ber-MAC-DRC): sc-19662 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

    Asked by: Trav11
    We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-24
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    Rated 5 out of 5 by from Worked well in IP stainingWe used this antibody for IP staining and were able to take great images of cells with the staining
    Date published: 2017-01-25
    Rated 3 out of 5 by from Produced nice immunoperoxidase membrane stainingProduced nice immunoperoxidase membrane staining in formalin-fixed, paraffin-embedded human tonsil tissue. -SCBT QC
    Date published: 2013-08-31
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    CD35 抗体 (Ber-MAC-DRC) is rated 4.0 out of 5 by 2.
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