Date published: 2026-10-24

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CD24 抗体 (3H1143): sc-70600

3.5(2)
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说明书
  • CD24抗体(3H1143)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 针对NALM-1 human前B白血病细胞系的抗体
  • 推荐用于 mouse, rat 和 human 来源的CD24 WB, IP, IF 和 FCM检测
  • 看 CD24 (SN3): sc-19585,可查看有标记的 CD24 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是CD24 Antibody (3H1143) for WB applications. 的首选辅助检测试剂,这些试剂现与CD24 Antibody (3H1143) 打包提供(请参阅下面的订购信息)。
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CD24是一种GPI连接的膜唾液酸糖蛋白,在pro-B、pre-B和成熟B细胞上表达,在B细胞活化后其表达降低。CD24也存在于粒细胞和一小部分胸腺细胞和神经母细胞瘤中,但不存在于浆细胞中。CD24可能在调节B细胞增殖和分化中发挥作用。CD24在血液恶性肿瘤和多种实体瘤中表达。CD24从顶端定位转变为胞浆染色的变化是交界性恶性肿瘤卵巢浆液性肿瘤间质侵袭的替代标志。CD24蛋白可以作为B细胞分化标志物,在成熟静息B细胞上表达,在刺激后消失。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CD24 抗体 (3H1143) 参考文献:

  1. CD24(+)细胞可促进肿瘤快速生长,并具有高度转移能力。  |  Rostoker, R., et al. 2015. Breast Cancer Res. 17: 78. PMID: 26040280
  2. CD24调节MCF-7乳腺癌细胞的化学敏感性。  |  Onishi, H., et al. 2017. Anticancer Res. 37: 561-565. PMID: 28179302
  3. CD24通过调节自噬来降低视网膜母细胞瘤对长春新碱的敏感性。  |  Sun, J., et al. 2020. Mol Oncol. 14: 1740-1759. PMID: 32394616
  4. 星形胶质细胞中CD24的敲除会加剧氧合血红蛋白引起的海马神经元损伤。  |  Chen, XX., et al. 2022. Neurochem Res. 47: 590-600. PMID: 34665391
  5. 树突状细胞表达的CD24有助于淋巴结中T淋巴细胞的优化启动。  |  Zhang, X., et al. 2023. Front Immunol. 14: 1116749. PMID: 36969215
  6. 吸入性外泌体经基因操作过度表达CD24(EXO-CD24),用于重症ARDS患者的同情使用。  |  Green, O., et al. 2023. Biomedicines. 11: PMID: 37760963
  7. IMM47是一种针对CD24的人源化单克隆抗体,通过阻断CD24/Siglec-10相互作用,表现出卓越的抗肿瘤功效,可作为单药疗法或与抗PD1抗体联合用于癌症免疫治疗。  |  Li, S., et al. 2023. Antib Ther. 6: 240-252. PMID: 37846296
  8. 在轻度至中度新冠肺炎相关性急性呼吸窘迫综合征中,外泌体过度表达CD24(EXO-CD24)的安全性和潜在功效。  |  Grigoropoulos, I., et al. 2024. Respir Res. 25: 151. PMID: 38561798
  9. 整合多组学分析揭示了乳腺癌CD24介导的免疫抑制肿瘤微环境的独特见解。  |  Hu, H., et al. 2024. Inflamm Res. 73: 1047-1068. PMID: 38622285
  10. LAT1抑制剂JPH203通过CD24介导的机制抑制去势抵抗性前列腺癌的生长。  |  Saito, S., et al. 2024. Cancer Sci. 115: 2461-2472. PMID: 38655663

订购信息

产品名称产品编号规格价格数量收藏夹

CD24 抗体 (3H1143)

sc-70600
200 µg/ml
CNY2422.00

CD24 (3H1143): m-IgG Fc BP-HRP 套装

sc-539300
200 µg Ab; 10 µg BP
CNY2715.00

CD24 (3H1143): m-IgG1 BP-HRP 套装

sc-541391
200 µg Ab; 20 µg BP
CNY2715.00

What is the difference between the anti- CD24 antibody (3H1143): sc-70600 and anti-CD24 antibody(SN3):sc-19585?

Asked by: Lan6083
Thank you for your question. There is no significant difference between these two antibodies. The original CD24 clone (SN3) has also been commercially available and published under the alternative clone designation (3H1143). Therefore we have assigned a separate catalog number so that customers can find the antibody under both clone names.
Answered by: Technical Support
Date published: 2019-08-02

What is the recommended fixation method for immunofluorescence staining with CD24 (3H1143): sc-70600 monoclonal antibody?

Asked by: Professor Griffin
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by SM from Produced clear immunofluorescence membraneProduced clear immunofluorescence membrane staining in methanol-fixed HeLa cells. -SCBT QC
Date published: 2015-03-08
Rated 3 out of 5 by LR from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-02-26
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CD24 抗体 (3H1143) is rated 3.5 out of 5 by 2.
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