Date published: 2025-9-10

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CBS 抗体 (B-4): sc-133154

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说明书
  • CBS 抗体 B-4 是小鼠单克隆 IgG1 κ,CBS抗体, 在27篇文献中引用,规格为200 µg/ml
  • 针对氨基酸101-400的图谱,在CBS的内部区域,human起源
  • CBS 抗体 (B-4) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 CBS
  • 抗CBS抗体(B-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取CBS (B-4): sc-133154免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRPm-IgGκ BP-HRP 是 CBS 抗体 (B-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与CBS 抗体 (B-4) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

CBS抗体(B-4)是一种IgG1 κ小鼠单克隆CBS抗体,可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的CBS蛋白。CBS抗体(B-4)既可作为非共轭抗CBS抗体形式提供,也可作为多种共轭抗CBS抗体形式提供,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®共轭物。胞质蛋白胱硫醚β-合酶(CBS)在人肝和胰腺中强表达,在心脏和大脑中表达较弱,在同型半胱氨酸转硫化作用的第一步中起作用。CBS属于半胱氨酸合酶/胱硫醚β-合酶蛋白家族,它使用磷酸吡哆醛辅因子催化血栓形成的氨基酸同型半胱氨酸形成胱硫醚。腺苷甲硫氨酸的别构激活调节CBS活性。CBS缺乏与胱硫醚尿症有关,这是一种隐性遗传的硫氨基酸代谢错误,影响许多器官和组织。胱硫醚尿症的症状包括动脉硬化、血栓形成、晶状体脱位、智力迟缓和骨骼异常。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CBS 抗体 (B-4) 参考文献:

  1. [缺血性中风患者同型半胱氨酸代谢相关酶的基因突变]。  |  Wu, JM., et al. 2004. Yi Chuan. 26: 298-302. PMID: 15640007
  2. 晶状体中存在转硫化途径:一种新的氧化应激防御系统。  |  Persa, C., et al. 2004. Exp Eye Res. 79: 875-86. PMID: 15642325
  3. 甲状腺切除大鼠体内同型半胱氨酸的再甲基化缺陷与辅酶 B2 的合成减少有关。  |  Ayav, A., et al. 2005. Amino Acids. 28: 37-43. PMID: 15645165
  4. 硫化氢在急性胰腺炎和相关肺损伤中的作用。  |  Bhatia, M., et al. 2005. FASEB J. 19: 623-5. PMID: 15671155
  5. [血浆同型半胱氨酸和胱硫醚-β-合成酶多态性与脑血栓形成的关系]。  |  Shao, Y., et al. 2005. Di Yi Jun Yi Da Xue Xue Bao. 25: 351-3. PMID: 15772012
  6. 铜对胱硫醚 beta 合成酶活性的抑制作用:人类白蛋白 N 端类似物的保护作用。  |  Bar-Or, D., et al. 2005. Protein Pept Lett. 12: 271-3. PMID: 15777277
  7. 氯离子转运 CLC 蛋白的独特结构和功能。  |  Pusch, M. and Jentsch, TJ. 2005. IEEE Trans Nanobioscience. 4: 49-57. PMID: 15816171
  8. 高同型半胱氨酸血症和动脉粥样硬化。  |  Yang, F., et al. 2005. Sheng Li Xue Bao. 57: 103-14. PMID: 15830093
  9. 外泌体lncRNA-H19通过在CBS杂合子小鼠中介导Angpt1/Tie2-NO信号促进骨形成和血管生成。  |  Behera, J., et al. 2021. Theranostics. 11: 7715-7734. PMID: 34335960
  10. 缺氧诱导lncRNA-CBSLR通过m6A-YTHDF2依赖性调节胃癌中CBS来调节铁死亡。  |  Yang, H., et al. 2022. J Adv Res. 37: 91-106. PMID: 35499052
  11. 载脂蛋白C1通过减少KEAP1/NRF2和CBS调控的铁凋亡促进胶质母细胞瘤肿瘤发生  |  Zheng, XJ., et al. 2022. Acta Pharmacol Sin. 43: 2977-2992. PMID: 35581292
  12. ATF3-CBS信号轴协调结肠直肠癌中的铁死亡和肿瘤发生。  |  Liu, J., et al. 2024. Redox Biol. 71: 103118. PMID: 38490069

订购信息

产品名称产品编号规格价格数量收藏夹

CBS 抗体 (B-4)

sc-133154
200 µg/ml
$316.00

CBS (B-4): m-IgG Fc BP-HRP 套装

sc-528754
200 µg Ab; 10 µg BP
$354.00

CBS (B-4): m-IgGκ BP-HRP 套装

sc-521253
200 µg Ab, 40 µg BP
$354.00

CBS (B-4): m-IgG1 BP-HRP 套装

sc-543112
200 µg Ab; 20 µg BP
$354.00

CBS 抗体 (B-4) AC

sc-133154 AC
500 µg/ml, 25% agarose
$416.00

CBS 抗体 (B-4) HRP

sc-133154 HRP
200 µg/ml
$316.00

CBS 抗体 (B-4) FITC

sc-133154 FITC
200 µg/ml
$330.00

CBS 抗体 (B-4) PE

sc-133154 PE
200 µg/ml
$343.00

CBS 抗体 (B-4) Alexa Fluor® 488

sc-133154 AF488
200 µg/ml
$357.00

CBS 抗体 (B-4) Alexa Fluor® 546

sc-133154 AF546
200 µg/ml
$357.00

CBS 抗体 (B-4) Alexa Fluor® 594

sc-133154 AF594
200 µg/ml
$357.00

CBS 抗体 (B-4) Alexa Fluor® 647

sc-133154 AF647
200 µg/ml
$357.00

CBS 抗体 (B-4) Alexa Fluor® 680

sc-133154 AF680
200 µg/ml
$357.00

CBS 抗体 (B-4) Alexa Fluor® 790

sc-133154 AF790
200 µg/ml
$357.00

I would appreciate if you can send me a sample to test on my fixed mice brain slices for IF.

Asked by: Budai
感谢您的提问。 我们小样申领都是随单赠送,您购买一支抗体,最多可以免费申领3支货号不同,目标蛋白不同的抗体小样。 Thank you for your question. We have a promotion with each primary antibody purchase you can recive 3 free antibody samples .
Answered by: Ling Chen
Date published: 2022-08-24

I would appreciate if you can send me a sample to test on my fixed mice brain tissue for western blot.

Asked by: Rupali Sharma
Thank you for your question. We would be happy to send you a free 10 µg sample of this antibody, CBS (B-4): sc-133154, to test before you place your order. Please contact our Technical Service Department to request a free sample. Please call us toll-free at (800) 457-3801 option 2, e-mail <[email protected]>, or use the live chat on our website.
Answered by: Technical Support
Date published: 2017-08-03

I would appreciate you sending me a 10 µg sample of CBS-133154(B-4) to test for reactivity in mouse BV2 microglial cells. Thank you.

Asked by: gmcbean
Thank you for your interest in our CBS (B-4) sc-133154. We would be happy to arrange the sample. Please contact our Europe Technical Service team by phone at Toll Free: +49 6221 4503 0, by email at: [email protected] or by live chat directly on our website, www.scbt.com to arrange the sample.
Answered by: Technical Service
Date published: 2017-07-14

Can CBS (B-4): sc-133154 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: DefinitelyNotMatt
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CBS (B-4): sc-133154 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Works great in Rat kidney cellsWe bought CBS primary antibody for Western blot application. We got distinct protein band in Rat kidney cells
Date published: 2022-06-04
Rated 5 out of 5 by from Review for CBS antibody(B-4)a good antibody,we used it for WB,when dilution in 1:1000,exposure just need 1 min.the band is about 70-80 KD.
Date published: 2017-03-13
Rated 5 out of 5 by from nice resultThis antibody detects target antigen without background in our studies, this has worked well in Western blotting for 1:1000.
Date published: 2017-02-11
Rated 5 out of 5 by from Antibody is really greatAntibody provides clear and specific results,antibody is really great.
Date published: 2017-02-07
Rated 5 out of 5 by from With a precise position effectCBS antibody shows hight express in rat spleen tissue. We tried it detect this sample from dilution 1:500, obtained specific band.
Date published: 2017-02-04
Rated 5 out of 5 by from Transfection with WB cleavage.Excellent immunoperoxidase staining in the cytoplasm of formalin fixed, paraffin embedded pancreatic tissue. Transfection with WB cleavage.
Date published: 2016-12-22
Rated 5 out of 5 by from Superb immunoperoxidase cytoplasmic stainingSuperb immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human pancreas tissue. -SCBT QC
Date published: 2015-04-25
Rated 4 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-02-15
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CBS 抗体 (B-4) is rated 4.8 out of 5 by 8.
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