Date published: 2026-10-20

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caveolin-3 Antibody (C-2) - Western Blotting - Image 377567
洞穴素-3 抗体 (C-2): sc-55518. Western 印迹分析 Sol8 全细胞裂解液 (A) 和小鼠心脏组织提取物 (B) 中 caveolin-3 的表达.
洞穴素-3 抗体 (C-2): sc-55518. Western 印迹分析 Sol8 全细胞裂解液 (A) 和小鼠心脏组织提取物 (B) 中 caveolin-3 的表达.

caveolin-3 抗体 (C-2): sc-55518

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说明书
  • caveolin-3抗体(C-2)是小鼠单克隆IgG1 κ, 在6篇文献中引用，规格为200 µg/ml
  • 特异性抗原位于mouse物种的caveolin-3的N-terminus的氨基酸3-40之间
  • 抗-caveolin-3 抗体 (C-2) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 caveolin-3
  • 抗caveolin-3抗体（C-2）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是caveolin-3 Antibody (C-2) for WB and IHC(P) applications. 的首选辅助检测试剂，这些试剂现与caveolin-3 Antibody (C-2) 打包提供（请参阅下面的订购信息）。
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関連項目

额外Caveolin抗体，包括caveolin-3

洞穴素-3 抗体（C-2）是一种小鼠单克隆 IgG1 kappa 轻链抗体，可通过免疫印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、免疫组织化学和酶联免疫吸附试验（ELISA）等应用检测小鼠、大鼠和人类样本中的洞穴素-3。抗 Caveolin-3 抗体（C-2）有非共轭型和多种共轭型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种 Alexa Fluor® 共轭物。Caveolin-3 主要位于细胞质膜中，是洞穴的重要组成部分，洞穴是烧瓶状的内陷，在内吞和信号转导等细胞过程中发挥着重要作用。这些结构对分隔信号分子（包括 G 蛋白偶联受体）至关重要，并促进大分子（如低密度脂蛋白）在内皮细胞中的转运。洞穴小泡中的 Caveolin-3 可维持细胞平衡并调节各种信号通路，因此 Caveolin-3 在心血管健康和疾病中具有重要作用。洞穴淋巴因子-3 还与洞穴淋巴因子-1 和洞穴淋巴因子-2 相互作用，它们在结构上有相似之处，在功能上也有相同的作用，这凸显了洞穴淋巴因子-3 在细胞信号传导和膜动力学中的重要作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

caveolin-3 抗体 (C-2) 参考文献:

  1. 靶向Caveolin-3治疗糖尿病性心肌病。  |  Murfitt, L., et al. 2015. Pharmacol Ther. 151: 50-71. PMID: 25779609
  2. Caveolin-3微域：钾内向整流器和心脏钠通道的心律失常影响。  |  Vaidyanathan, R., et al. 2018. Front Physiol. 9: 1548. PMID: 30473666
  3. Caveolin-3在肌肉萎缩症发病机理中的作用。  |  Pradhan, BS. and Prószyński, TJ. 2020. Int J Mol Sci. 21: PMID: 33228026
  4. 蛋白质相互作用的世界：定义Caveolin-3心脏相互作用组。  |  Van Eyk, JE. 2021. Circ Res. 128: 720-722. PMID: 33734816
  5. Caveolin-3与心律失常：分子机制研究。  |  He, M., et al. 2022. J Clin Med. 11: PMID: 35329921
  6. Caveolin 3抑制肌膜nNOS的磷酸化依赖性激活。  |  Ohsawa, Y., et al. 2022. Biochem Biophys Res Commun. 628: 84-90. PMID: 36084555
  7. 功能性LTCC-β2AR复合物需要Caveolin-3，在心力衰竭中会受到破坏。  |  Sanchez-Alonso, JL., et al. 2023. Circ Res. 133: 120-137. PMID: 37313722
  8. Caveolin-3缺失与LGMD-1C的P104L突变有关，可调节骨骼肌mTORC1信号传导和胆固醇稳态。  |  Shah, DS., et al. 2023. J Cachexia Sarcopenia Muscle. 14: 2310-2326. PMID: 37671684
  9. Caveolin-3负调控心脏KATP通道的内吞循环。  |  Huo, JY., et al. 2023. Am J Physiol Cell Physiol. 325: C1106-C1118. PMID: 37746698
  10. 半胱氨酸翻译后修饰调节Caveolin-3的蛋白质相互作用。  |  Ashford, F., et al. 2024. FASEB J. 38: e23535. PMID: 38466300

订购信息

产品名称产品编号规格价格数量收藏夹

caveolin-3 抗体 (C-2)

sc-55518
200 µg/ml
CNY2422.00

caveolin-3 (C-2): m-IgG Fc BP-HRP 套装

sc-526861
200 µg Ab; 10 µg BP
CNY2715.00

caveolin-3 (C-2): m-IgG1 BP-HRP 套装

sc-532234
200 µg Ab; 20 µg BP
CNY2715.00

caveolin-3 抗体 (C-2) AC

sc-55518 AC
500 µg/ml, 25% agarose
CNY3189.00

caveolin-3 抗体 (C-2) HRP

sc-55518 HRP
200 µg/ml
CNY2422.00

caveolin-3 抗体 (C-2) FITC

sc-55518 FITC
200 µg/ml
CNY2527.00

caveolin-3 抗体 (C-2) PE

sc-55518 PE
200 µg/ml
CNY2625.00

caveolin-3 抗体 (C-2) Alexa Fluor® 488

sc-55518 AF488
200 µg/ml
CNY2738.00

caveolin-3 抗体 (C-2) Alexa Fluor® 546

sc-55518 AF546
200 µg/ml
CNY2738.00

caveolin-3 抗体 (C-2) Alexa Fluor® 594

sc-55518 AF594
200 µg/ml
CNY2738.00

caveolin-3 抗体 (C-2) Alexa Fluor® 647

sc-55518 AF647
200 µg/ml
CNY2738.00

caveolin-3 抗体 (C-2) Alexa Fluor® 680

sc-55518 AF680
200 µg/ml
CNY2738.00

caveolin-3 抗体 (C-2) Alexa Fluor® 790

sc-55518 AF790
200 µg/ml
CNY2738.00

caveolin-3 (C-2) 中和勝肽

sc-55518 P
100 µg/0.5 ml
CNY519.00

What application is the blocking peptide sc-55518 P appropriate for?

Asked by: jenni
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support 14
Date published: 2017-02-07
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Rated 5 out of 5 by LuciaP from Antibody with great sensitivityAntibody with high sensitivity and specificity. Used for WB against human protein.
Date published: 2022-10-17
Rated 5 out of 5 by cjMara from Solid choice for caveolin-3The (C-2) clone for caveolin-3 is a solid choice for WB and IHC(P). However, alternate clone (A-3), sc-5310, is the preferred and more popular choice based on excellent in-house data and numerous product citations.
Date published: 2017-01-23
Rated 4 out of 5 by FL from Robust band seen in WB using SJRH30 wholeRobust band seen in WB using SJRH30 whole cell lysate. -SCBT QC
Date published: 2015-05-07
Rated 5 out of 5 by CJ from Publishable data in WB using human skeletal musclePublishable data in WB using human skeletal muscle. -SCBT Publication Review
Date published: 2015-04-26
Rated 4 out of 5 by MS from Publishable data in IF using mouse myocardiumPublishable data in IF using mouse myocardium. -SCBT Publication Review
Date published: 2015-04-23
Rated 4 out of 5 by HC from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-04-05
Rated 4 out of 5 by JM from Publishable data in WB using mouse smallPublishable data in WB using mouse small intestinal cell lines. -SCBT Publication Review
Date published: 2015-02-27
Rated 5 out of 5 by JM from Excellent immunoperoxidase cytoplasmic andExcellent immunoperoxidase cytoplasmic and membrane staining in formalin fixed, paraffin-embedded human heart muscle tissue. -SCBT QC
Date published: 2015-01-19
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caveolin-3 抗体 (C-2) is rated 4.5 out of 5 by 8.
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