Date published: 2025-9-11

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cAMP 抗体 (AM01): sc-73761

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说明书
  • cAMP 抗体 AM01 是小鼠单克隆 IgG1cAMP抗体, 在5篇文献中引用,规格为50 µg/0.5 ml
  • 针对cAMP
  • 推荐用于检测cAMP(由IF提供
  • 关于如何获取cAMP (AM01): sc-73761免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是cAMP Antibody (AM01). 的首选辅助检测试剂,这些试剂现与cAMP Antibody (AM01) 打包提供(请参阅下面的订购信息)。

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関連項目

cAMP Antibody (AM01) 是一种 IgG1 鼠源单克隆 cAMP 抗体(也称为 cAMP 抗体),可通过免疫荧光 (IF) 检测 cAMP 蛋白。cAMP 抗体 (AM01) 可作为非偶联形式的抗-cAMP 抗体提供。cAMP(环腺苷酸),一种环核苷酸,在许多信号转导途径中作为普遍存在的胞质第二信使起着重要作用。cAMP 是由腺苷酸环化酶通过从 ATP 中去除一个焦磷酸分子生成的。腺苷酸环化酶的激活通常与配体与其 G 蛋白偶联受体的结合相关。腺苷酸环化酶的激活增加了细胞内 cAMP 的浓度,从而允许 cAMP 依赖性蛋白激酶的激活。激活的激酶放大了信号,磷酸化了许多蛋白质并改变了细胞活动。cAMP 是一个关键的细胞内调节因子;它介导了许多激素的活动,包括 ACTH、胰高血糖素和肾上腺素,并在调节钙运输、基因激活和诱导对生长、分化和神经传递的生理反应中发挥重要作用。cAMP 的降解受磷酸二酯酶的控制。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

cAMP 抗体 (AM01) 参考文献:

  1. 中性粒细胞中 G alpha s 链接受体的占据使化学吸引受体与其刺激-转导机制脱钩。  |  Cronstein, BN., et al. 1992. Blood. 80: 1052-7. PMID: 1323344
  2. 急性心肌梗死合并心力衰竭时的单磷酸环磷酸腺苷:杀手还是救星?  |  Leineweber, K., et al. 2006. Circulation. 114: 365-7. PMID: 16880340
  3. 调节子宫松弛的环磷酸腺苷信号通路。  |  Yuan, W. and López Bernal, A. 2007. BMC Pregnancy Childbirth. 7 Suppl 1: S10. PMID: 17570154
  4. 超越 GPCR/G 蛋白激活的 cAMP 合成调控新见解:对心血管调控的影响。  |  Feldman, RD. and Gros, R. 2007. Life Sci. 81: 267-71. PMID: 17604058
  5. 罗利普仑是一种磷酸二酯酶 4 抑制剂,它通过抑制卵巢切除成年大鼠骨内膜骨吸收和维持骨膜骨形成增高来防止松质骨和皮质骨流失。  |  Yao, W., et al. 2007. J Musculoskelet Neuronal Interact. 7: 119-30. PMID: 17627081
  6. 环 AMP 增强剂和 Abeta 低聚物阻断剂作为阿尔茨海默病的潜在治疗药物。  |  De Felice, FG., et al. 2007. Curr Alzheimer Res. 4: 263-71. PMID: 17627483
  7. 钙信使系统在促肾上腺皮质激素诱导牛肾上腺筋膜网状细胞产生皮质醇过程中的作用  |  Omura, M., et al. 2007. Endocr J. 54: 585-92. PMID: 17634670
  8. 1,25-二羟维生素 D3 通过阻断肾素基因启动子中环 AMP 反应元件的活性,抑制肾素基因的转录。  |  Yuan, W., et al. 2007. J Biol Chem. 282: 29821-30. PMID: 17690094
  9. 直接激活 Rap1 的 cAMP 结合蛋白家族。  |  Kawasaki, H., et al. 1998. Science. 282: 2275-9. PMID: 9856955

订购信息

产品名称产品编号规格价格数量收藏夹

cAMP 抗体 (AM01)

sc-73761
50 µg/0.5 ml
RMB2377.00

cAMP (AM01): m-IgG Fc BP-HRP 套装

sc-539506
50 µg Ab; 10 µg BP
RMB2662.00

cAMP (AM01): m-IgG1 BP-HRP 套装

sc-541531
50 µg Ab; 20 µg BP
RMB2662.00

Can I assume this antibody [cAMP Antibody (AM01): sc-73761)] can detect cAMP in all cells of all animals (mouse, rat, human etc)?

Asked by: Antibodyuser
Thank you for contacting Santa Cruz Biotechnology . Yes, sc-73761 cAMP (AM01) is recommended on mouse, rat and human samples .
Answered by: BlakeJ
Date published: 2024-07-15

Do you predict that this Ab will work on paraffin IHC since it works well in IF? Any experience? What is the reactivity? Hu, M, Rb?

Asked by: Stergios
Thank you for your question. The antibody is recommended for IF. We cannot guarantee that it is going to work also on IHC(P).Please contact our Technical Service Department for additional information regarding this product.
Answered by: SCBT Heidelberg Support
Date published: 2018-12-21

What is the total volume provided of cAMP (AM01): sc-73761 monoclonal antibody?

Asked by: Dr Ninau Qelp
Thank you for your question. This antibody is provided as 100 µg in 1 ml total volume.
Answered by: Technical Support
Date published: 2017-03-07
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Rated 5 out of 5 by from Good choice for Immunoperoxidase stainingThis antibody has been used for Immunoperoxidase staining in published research. -SCBT QC
Date published: 2023-09-14
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cAMP 抗体 (AM01) is rated 3.5 out of 5 by 2.
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