Date published: 2025-9-6

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CaMKII delta 抗体 (L-04): sc-100362

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说明书
  • CaMKII delta抗体(L-04)是小鼠单克隆IgG2b λ CaMKII delta抗体, 在13篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组CaMKIIδ
  • 推荐用于 mouse, rat 和 human 来源的CaMKIIδ WB, IP, IF 和 ELISA检测
  • 关于如何获取CaMKII delta (L-04): sc-100362免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 2b BP-HRP">m-IgG2b BP-HRP是CaMKII delta Antibody (L-04) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与CaMKII delta Antibody (L-04) 打包提供(请参阅下面的订购信息)。

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関連項目

CaMKIIδ抗体(L-04)是一种小鼠单克隆IgG2b抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附(ELISA)等方法检测小鼠、大鼠和人类样本中的CaMKIIδ。抗CaMKIIδ抗体(L-04)以非结合形式提供。CaMKII delta在各种细胞过程中发挥着关键作用,特别是在调节大脑突触可塑性和记忆形成方面。CaMKII delta主要位于神经元的突触后密度中,参与磷酸化各种底物,从而调节突触强度和神经元信号通路。CaMKII delta的正常功能对于长期增强(一种学习和记忆的细胞机制)至关重要。CaMKII delta的失调与多种神经系统疾病有关,因此CaMKII delta成为神经生物学研究和潜在治疗干预的重要目标。抗CaMKII delta抗体(L-04)能够跨物种识别CaMKII delta,从而提高了其在比较研究和转化研究中的实用性,为突触功能和功能障碍的分子机制提供了宝贵的见解。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CaMKII delta 抗体 (L-04) 参考文献:

  1. 心脏肌浆网磷酰班激酶是一种独特的 delta-CaM 激酶同工酶。  |  Baltas, LG., et al. 1995. FEBS Lett. 373: 71-5. PMID: 7589437
  2. 钙离子/钙调蛋白依赖性蛋白激酶级联的特征。钙/钙调蛋白依赖性蛋白激酶激酶的分子克隆和表达。  |  Tokumitsu, H., et al. 1995. J Biol Chem. 270: 19320-4. PMID: 7642608
  3. 钙/钙调蛋白依赖性蛋白激酶II能下调人类T细胞中钙调素和蛋白激酶C介导的细胞因子基因转录途径。  |  Hama, N., et al. 1995. J Exp Med. 181: 1217-22. PMID: 7869038
  4. KN-93 是 CaMK-II(多功能 Ca2+/CaM 激酶)的一种阻抑剂,可诱导 NIH 3T3 细胞的 G1 细胞周期停滞和细胞凋亡。  |  Tombes, RM., et al. 1995. Cell Growth Differ. 6: 1063-70. PMID: 8519682
  5. 过表达 Ca2+/calmodulin 依赖性蛋白激酶 II 可抑制 PC12 细胞的神经元生长。  |  Tashima, K., et al. 1996. J Neurochem. 66: 57-64. PMID: 8522989
  6. Jurkat T 淋巴细胞中 CaM 激酶对 Ca2+/calmodulin 依赖性蛋白激酶(CaM-激酶)IV 的激活。  |  Park, IK. and Soderling, TR. 1995. J Biol Chem. 270: 30464-9. PMID: 8530476

订购信息

产品名称产品编号规格价格数量收藏夹

CaMKII delta 抗体 (L-04)

sc-100362
100 µg/ml
RMB2504.00

CaMKII delta (L-04): m-IgG2b BP-HRP 套装

sc-548469
100 µg Ab; 10 µg BP
RMB2662.00

CaMKII delta抗体(L-04): sc-100362に関しまして、具体的にCAMKIIdのどの領域を抗体認識領域としていますか?CaMKIIdには複数のスプライシングバリアントがあるようなので、この抗体ではどのスプライシングバリアントに対応しているのか教えてください

Asked by: k228704
Thank you for your question. This antibody epitopes to amino acids 301-410 of human CaMKIIα. Please refer to the following genomic information: https://www.uniprot.org/uniprotkb/Q13557/entry#sequences ご質問ありがとうございます。この抗体はヒト由来のCaMKIIαのアミノ酸301-410にエピトープしています。以下のゲノム情報をご参照ください。https://www.uniprot.org/uniprotkb/Q13557/entry#sequences
Answered by: Jiajun Z
Date published: 2025-01-21

What is the recommended starting dilution for Western blot for CaMKIIδ (L-04): sc-100362?

Asked by: jenni
Thank you for your question. The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, can be found in the “datasheet” link at the top of the product page, for which I have provided the link: https://datasheets.scbt.com/sc-100362.pdf If you have any further questions or concerns, please contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Answered by: Technical Support 8
Date published: 2017-01-26
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Rated 5 out of 5 by from 抗体还可以抗体很好用,相比其他公司,便宜大碗,条带清晰,杂带少。。。。。。。。。。。。。。。。。。。。。。。。。
Date published: 2019-06-14
Rated 5 out of 5 by from Very nice staining in P19 cellsDilution 1/50 Used for immunocytochemistry on cultured neurons : very low staining . So I used P19 cells as positive control: very nice staining!
Date published: 2018-01-16
Rated 5 out of 5 by from Great resultsThe main ban is very strong, and background is very clear.
Date published: 2017-10-03
Rated 5 out of 5 by from Great monoSingle band detected by WB and specific staining observed by IF with CaMKII delta Antibody (L-04)
Date published: 2017-01-19
Rated 3 out of 5 by from Satisfactory immunofluorescence cytoplasmicSatisfactory immunofluorescence cytoplasmic staining in paraformaldehyde-fixed NIH/3T3 cells. -SCBT QC
Date published: 2015-04-17
Rated 5 out of 5 by from Clean band on Western Blot with this antibodyClean band on Western Blot with this antibody used on human CaMKII transfected 293T whole cell lysate. -SCBT QC
Date published: 2015-03-25
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CaMKII delta 抗体 (L-04) is rated 4.7 out of 5 by 6.
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